Christopher McCormack
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Cutaneous Infiltration of Waldenstrom's Macroglobulinaemia—A Two‐Case Series of a Diagnostically Challenging Presentation Open
Background/Objectives Cutaneous manifestations of Waldenstrom's macroglobulinaemia (WM), a rare B‐cell lymphoproliferative disorder, present a diagnostic challenge. The intent of this article is to raise awareness to clinicians of a potent…
View article: Radiotherapy dose–response of mycosis fungoides with large cell transformation
Radiotherapy dose–response of mycosis fungoides with large cell transformation Open
LCTMF is radio-responsive, with EQD2 >12.0 Gy associated with 100 % ORR. Dose-response was observed, with EQD2 >36.0 Gy achieving 100 % CR rate. For unifocal cutaneous LCTMF, RT-alone achieved excellent infield control with possible curati…
View article: Large‐cell transformation of mycosis fungoides: Patterns of care and patient outcomes
Large‐cell transformation of mycosis fungoides: Patterns of care and patient outcomes Open
Summary Large‐cell transformation of mycosis fungoides (LCTMF) is rare, histologically distinct, with an aggressive clinical course; yet is not recognised as an independent entity in classification systems nor in staging systems for mycosi…
View article: Eight‐Year Experience of Hedgehog Pathway Inhibitors at Three Tertiary Referral Centres in the Australian State of Victoria
Eight‐Year Experience of Hedgehog Pathway Inhibitors at Three Tertiary Referral Centres in the Australian State of Victoria Open
This retrospective analysis of Hedgehog inhibitor treatment in 32 patients with Gorlin syndrome, locally advanced and metastatic basal cell carcinoma (BCC) at three tertiary referral centres in Victoria, Australia from April 2017 until 30 …
Complete skin remission of Sneddon‐Wilkinson disease with acalabrutinib Open
Sneddon‐Wilkinson (SW) disease is rare condition which typically occurs in the context of a monoclonal immunoglobulin and treatment options have not been well studied. Here we present a case of a 65‐year‐old female with SW with underlying,…
Improving disease‐specific survival for patients with Sezary syndrome in the modern era of systemic therapies Open
Summary Traditionally, Sezary syndrome (SS) has been associated with few therapeutic options and poor prognosis, with 5‐year disease‐specific survival (DSS) less than one‐third in historical cohorts. However, newer therapies and combinatio…
Management of Skin Toxicities in Cancer Treatment: An Australian/New Zealand Perspective Open
Cancer systemic therapeutics and radiotherapy are often associated with dermatological toxicities that may reduce patients’ quality of life and impact their course of cancer treatment. These toxicities cover a wide range of conditions that…
<span>CD30</span>‐positive lymphoproliferative disorders—An Australian Clinical Practice Statement from the Peter <span>MacCallum</span> Cancer Centre Open
The CD30‐postive lymphoproliferative disorders, including lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma, account for up to 30% of all cutaneous T‐cell lymphomas (CTCLs) and are the second most common form of C…
Development of melanoma clinical quality indicators for the Australian melanoma clinical outcomes registry (<span>MelCOR</span>): A modified Delphi study Open
Background Clinical quality registries aim to identify significant variations in care and provide anonymised feedback to institutions to improve patient outcomes. Thirty‐six Australian organisations with an interest in melanoma, raised fun…
Impact of chronic lymphocytic leukaemia on melanoma outcomes: A retrospective case‐control study Open
Summary With new, effective treatments for chronic lymphocytic leukaemia (CLL) the impact of second malignancies is increasingly important. We performed a retrospective case‐controlled study examining the effect of CLL and its treatment on…
Patients’ Experiences of Using Skin Self-monitoring Apps With People at Higher Risk of Melanoma: Qualitative Study Open
Background Melanoma is the fourth most commonly diagnosed cancer in Australia. Up to 75% of melanomas are first detected by patients or their family or friends. Many mobile apps for melanoma exist, including apps to encourage skin self-mon…
Mycosis fungoides and Sézary syndrome: Australian clinical practice statement Open
Primary cutaneous lymphomas represent a heterogeneous group of T‐ and B‐cell lymphomas with distinct clinical presentations, histopathologic features, treatment approaches and outcomes. The cutaneous T‐cell lymphomas, which include mycosis…
Time to Next Treatment as a Meaningful Endpoint for Trials of Primary Cutaneous Lymphoma Open
Time to next treatment (TTNT) is an emerging endpoint in clinical studies of primary cutaneous T-cell lymphomas (CTCL), with utility as a surrogate marker for the “duration of clinical benefit”. TTNT provides a highly clinically meaningful…
Using the Principle of Scaling to Improve Skill Acquisition and the Overall Sporting Experience in Children’s Sport Open
This book will be a source for communicating sports human factors and ergonomics research, showcase key issues, and inspire further applications...
Patients’ Experiences of Using Skin Self-monitoring Apps With People at Higher Risk of Melanoma: Qualitative Study (Preprint) Open
BACKGROUND Melanoma is the fourth most commonly diagnosed cancer in Australia. Up to 75% of melanomas are first detected by patients or their family or friends. Many mobile apps for melanoma exist, including apps to encourage skin self-mon…
Lack of Durable Remission with Conventional-Dose Total Skin Electron Therapy for the Management of Sezary Syndrome and Multiply Relapsed Mycosis Fungoides Open
Mycosis fungoides (MF) and Sezary syndrome (SS) are multi-relapsing, morbid, cutaneous T-cell lymphomas. Optimal treatment sequencing remains undefined. Total skin electron therapy (TSE) is a highly technical, skin-directed treatment, uniq…
Pembrolizumab‐induced sarcoid granulomatous panniculitis and bullous pemphigoid in a single patient Open
Key Clinical Message Pembrolizumab is an immune checkpoint inhibitor with antitumor activity in other organ malignancies. We present this case —demonstrating multiple inflammatory adverse events associated with Pembrolizumab (in a single p…
Flashes of modernity: stage design at the Abbey Theatre, 1902-1966 Open
Responding to Guy Julier’s call for a “knowing practice” of design studies, this doctoral thesis reveals Ireland’s negotiation with modernity through stage design. I use historian T.J. Clark’s definition of modernity as “contingency,” whic…
Corrections to “Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: a multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium” Open
Background Advanced-stage mycosis fungoides (MF)/Sezary syndrome (SS) patients are weighted by an unfavorable prognosis and share an unmet clinical need of effective treatments. International guidelines are available detailing treatment op…
Surveillance imaging with FDG-PET/CT in the post-operative follow-up of stage 3 melanoma Open
As early detection of recurrent melanoma maximizes treatment options, patients usually undergo post-operative imaging surveillance, increasingly with FDG-PET/CT (PET). To assess this, we evaluated stage 3 melanoma patients who underwent pr…