Christopher Mow
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View article: Gestational Weight Gain and Pregnancy Outcomes After GLP-1 Receptor Agonist Discontinuation
Gestational Weight Gain and Pregnancy Outcomes After GLP-1 Receptor Agonist Discontinuation Open
Importance Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are contraindicated in pregnancy. Discontinuation of GLP-1RAs proximal to pregnancy could affect gestational weight gain and pregnancy outcomes. Objective To compare gestation…
View article: Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study
Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study Open
Objectives Pregnancy alters hematologic state as measured by complete blood counts (CBC), but the longitudinal changes in CBC indices that define healthy pregnancies are not well established. Our objectives were (1) to define gestational a…
View article: Estimating Glycemia From HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy
Estimating Glycemia From HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy Open
OBJECTIVE To examine the accuracy of different periods of continuous glucose monitoring (CGM), hemoglobin A1c (HbA1c), and their combination for estimating mean glycemia over 90 days (AG90). RESEARCH DESIGN AND METHODS We retrospectively s…
View article: Estimating Glycemia from HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy
Estimating Glycemia from HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy Open
Objective. To examine the accuracy of different periods of continuous glucose monitoring (CGM), hemoglobin A1c (HbA1c), and their combination for estimating mean glycemia over 90 days (AG90).Research Design and Methods. We retrospectively …
View article: Estimating Glycemia from HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy
Estimating Glycemia from HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy Open
Objective. To examine the accuracy of different periods of continuous glucose monitoring (CGM), hemoglobin A1c (HbA1c), and their combination for estimating mean glycemia over 90 days (AG90).Research Design and Methods. We retrospectively …
View article: Hematologic setpoints are a stable and patient-specific deep phenotype
Hematologic setpoints are a stable and patient-specific deep phenotype Open
The complete blood count is an important screening tool for healthy adults and is the most commonly ordered test at periodic physical exams. However, results are usually interpreted relative to one-size-fits-all reference intervals, underm…
View article: Computer vision quantitation of erythrocyte shape abnormalities provides diagnostic, prognostic, and mechanistic insight
Computer vision quantitation of erythrocyte shape abnormalities provides diagnostic, prognostic, and mechanistic insight Open
Examination of red blood cell (RBC) morphology in peripheral blood smears can help diagnose hematologic diseases, even in resource-limited settings, but this analysis remains subjective and semiquantitative with low throughput. Prior attem…
View article: Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors
Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors Open
Background: Researchers routinely evaluate novel biomarkers for incorporation into clinical risk models, weighing tradeoffs between cost, availability, and ease of deployment. For risk assessment in population health initiatives, ideal inp…
View article: Primary Prostatic Carcinoma With De Novo Diffuse Neuroendocrine Differentiation
Primary Prostatic Carcinoma With De Novo Diffuse Neuroendocrine Differentiation Open
The 2016 World Health Organization classification of prostate cancer with neuroendocrine (NE) differentiation includes NE cells in usual prostate cancer, adenocarcinoma with Paneth cell-like NE differentiation, well-differentiated NE tumor…
View article: Scalable cardiovascular risk assessment using artificial intelligence-enabled event adjudication and widely available hematologic predictors
Scalable cardiovascular risk assessment using artificial intelligence-enabled event adjudication and widely available hematologic predictors Open
Introduction Researchers routinely evaluate novel biomarkers for incorporation into clinical risk models. Although of potential benefit, such emerging markers, which are often costly or not yet commercially available, are unlikely to enabl…
View article: Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection
Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection Open
Elevated RDW at the time of hospital admission and an increase in RDW during hospitalization were associated with increased mortality risk for patients with COVID-19 who received treatment at 4 hospitals in a large academic medical center …
View article: Elevated RDW is Associated with Increased Mortality Risk in COVID-19
Elevated RDW is Associated with Increased Mortality Risk in COVID-19 Open
Background Coronavirus disease 2019 (COVID-19) is an acute respiratory illness with a high rate of hospitalization and mortality. Prognostic biomarkers are urgently needed. Red blood cell distribution width (RDW), a component of complete b…
View article: Outpatient Total Joint Arthroplasty-Can It Be Done Safely? : A Review
Outpatient Total Joint Arthroplasty-Can It Be Done Safely? : A Review Open
Total knee arthroplasty and total hip arthroplasty are one of the most successful procedures treating patients with later stage of osteoarthritis. With an improvement of patient care, in every step from pre-operation, intra-operation an…