Christopher Wallenhorst
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View article: Atrial Fibrillation Detected by Handheld ECG and Ischemic Stroke Risk in a 55- to 64-Year-Old Chinese Population
Atrial Fibrillation Detected by Handheld ECG and Ischemic Stroke Risk in a 55- to 64-Year-Old Chinese Population Open
Although diagnostic yield of AF screening in Chinese patients aged 55 to 64 years is low, those with AF are at increased stroke risk and may warrant being on anticoagulation.
View article: Correction: Optimal length and temporal resolution of dynamic contrast-enhanced MR imaging for the differentiation between prostate cancer and normal peripheral zone tissue
Correction: Optimal length and temporal resolution of dynamic contrast-enhanced MR imaging for the differentiation between prostate cancer and normal peripheral zone tissue Open
[This corrects the article DOI: 10.1371/journal.pone.0287651.].
View article: The budget impact of implementing atrial fibrillation-screening in European countries
The budget impact of implementing atrial fibrillation-screening in European countries Open
A budget impact analysis estimates the short-term difference between the cost of the current treatment strategy and a new treatment strategy, in this case to implement population screening for atrial fibrillation (AF). The aim of this stud…
View article: Comparison of Clinical Outcomes in Patients with Active Cancer Receiving Rivaroxaban or Low-Molecular-Weight Heparin: The OSCAR-UK Study
Comparison of Clinical Outcomes in Patients with Active Cancer Receiving Rivaroxaban or Low-Molecular-Weight Heparin: The OSCAR-UK Study Open
Background In most patients with cancer-associated venous thromboembolism (CT), essentially those not at high risk of bleeding, guidelines recommend treatment with direct oral anticoagulants as an alternative to low-molecular-weight hepari…
View article: OC 54.1 Effectiveness and Safety of Rivaroxaban and Low Molecular-Weight Heparin in Cancer-Associated Venous Thromboembolism: A Meta-Analysis of Oscar Programme Findings
OC 54.1 Effectiveness and Safety of Rivaroxaban and Low Molecular-Weight Heparin in Cancer-Associated Venous Thromboembolism: A Meta-Analysis of Oscar Programme Findings Open
View article: Optimal length and temporal resolution of dynamic contrast-enhanced MR imaging for the differentiation between prostate cancer and normal peripheral zone tissue
Optimal length and temporal resolution of dynamic contrast-enhanced MR imaging for the differentiation between prostate cancer and normal peripheral zone tissue Open
The value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the detection of prostate cancer is controversial. There are currently insufficient peer reviewed published data or expert consensus to support routine adoption…
View article: Intravenous immunoglobulin and the current risk of moderate and severe anaphylactic events, a cohort study
Intravenous immunoglobulin and the current risk of moderate and severe anaphylactic events, a cohort study Open
This large cohort study from the US Premier Healthcare Database evaluated the risk and predictors of anaphylaxis in association with intravenous immunoglobulin (IvIg) therapy in the inpatient and outpatient setting. Data were collected ret…
View article: Refined atrial fibrillation screening and cost-effectiveness in the German population
Refined atrial fibrillation screening and cost-effectiveness in the German population Open
Objective Little is known on optimal screening population for detecting new atrial fibrillation (AF) in the community. We describe characteristics and estimate cost-effectiveness for a single timepoint electrocardiographic screening. Metho…
View article: <scp>Anti‐A/B</scp> isoagglutinin reduction in an intravenous immunoglobulin product and risk of hemolytic anemia: a hospital‐based cohort study
<span>Anti‐A/B</span> isoagglutinin reduction in an intravenous immunoglobulin product and risk of hemolytic anemia: a hospital‐based cohort study Open
BACKGROUND Intravenous immunoglobulins (IVIG) are derived from large human plasma pools. IVIG‐associated hemolytic anemia (HA) is a known class effect, likely attributed to dose‐dependent passive transfer of anti‐A/B isoagglutinins. Two is…
View article: Prediction of significant bleeding during vitamin K antagonist treatment for venous thromboembolism in outpatients
Prediction of significant bleeding during vitamin K antagonist treatment for venous thromboembolism in outpatients Open
Summary Bleeding is the most concerning complication associated with anticoagulant therapy but poorly characterized and important for risk/benefit assessment. We developed a risk stratification score to predict vitamin K antagonist (VKA)‐a…
View article: Ischemic Stroke and Transient Ischemic Attack Risk Following Vitamin K Antagonist Cessation in Newly Diagnosed Atrial Fibrillation: A Cohort Study
Ischemic Stroke and Transient Ischemic Attack Risk Following Vitamin K Antagonist Cessation in Newly Diagnosed Atrial Fibrillation: A Cohort Study Open
Background In nonvalvular atrial fibrillation ( AF ), oral anticoagulants prevent ischemic strokes and transient ischemic attacks ( TIAs ), but nonpersistence with vitamin K antagonist ( VKA ) oral anticoagulant therapy (20–50% at 1 year) …
View article: Incidence of Lyme disease in the UK: a population-based cohort study
Incidence of Lyme disease in the UK: a population-based cohort study Open
Objectives The purpose of this study was to estimate the annual incidence of Lyme disease (LD) in the UK. Design This was a retrospective descriptive cohort study. Setting Study data were extracted from the Clinical Practice Research Datal…
View article: Incidence and risk factors of chronic thromboembolic pulmonary hypertension following venous thromboembolism, a population‐based cohort study in England
Incidence and risk factors of chronic thromboembolic pulmonary hypertension following venous thromboembolism, a population‐based cohort study in England Open
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of unresolved organised pulmonary emboli/thrombi obstructing the major pulmonary arteries. The aim of this study was to estimate the incidence and risk factors of CTEP…
View article: Impact of screening and exclusion of high anti‐A titer donors on the risk of hemolytic anemia with intravenous immunoglobulin treatment: A hospital‐based cohort study in the US
Impact of screening and exclusion of high anti‐A titer donors on the risk of hemolytic anemia with intravenous immunoglobulin treatment: A hospital‐based cohort study in the US Open
Hemolytic anemia is a potential complication of administration of intravenous immunoglobulin preparations (IVIG).1 The hypothesized predominant mechanism is the passive acquisition of A and B isoagglutinins (anti-A and anti-B antibodies) f…
View article: 1190Lifestyle risk factors for non-valvular atrial fibrillation
1190Lifestyle risk factors for non-valvular atrial fibrillation Open
View article: Increasing incidence of non-valvular atrial fibrillation in the UK from 2001 to 2013
Increasing incidence of non-valvular atrial fibrillation in the UK from 2001 to 2013 Open
Objective To determine whether the incidence of atrial fibrillation (AF) is static or rising in the UK. Design Among the cohort of all individuals aged ≥45 years in the UK Clinical Practice Research Datalink (CPRD) (linked to hospital disc…