Christopher Woll
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View article: Risk of serious bacterial infections in pediatric patients with hyperpyrexia
Risk of serious bacterial infections in pediatric patients with hyperpyrexia Open
Objectives Hyperpyrexia has been associated with a greater prevalence of bacterial infections in the pediatric population, which prior to routine childhood vaccinations, has led to invasive testing and empiric antibiotic use for urinary tr…
View article: Association of Early Steroid Administration With Outcomes of Children Hospitalized for COVID-19 Without Multisystem Inflammatory Syndrome in Children
Association of Early Steroid Administration With Outcomes of Children Hospitalized for COVID-19 Without Multisystem Inflammatory Syndrome in Children Open
Importance There is limited evidence for therapeutic options for pediatric COVID-19 outside of multisystem inflammatory syndrome in children (MIS-C). Objective To determine whether the use of steroids within 2 days of admission for non–MIS…
View article: SARS-CoV-2 With Concurrent Respiratory Viral Infection as a Risk Factor for a Higher Level of Care in Hospitalized Pediatric Patients
SARS-CoV-2 With Concurrent Respiratory Viral Infection as a Risk Factor for a Higher Level of Care in Hospitalized Pediatric Patients Open
Objective As of early 2021, there have been over 3.5 million pediatric cases of SARS-CoV-2, including 292 pediatric deaths in the United States. Although most pediatric patients present with mild disease, they are still at risk for develop…
View article: Characteristics of Afebrile Infants ≤60 Days of Age With Invasive Bacterial Infections
Characteristics of Afebrile Infants ≤60 Days of Age With Invasive Bacterial Infections Open
OBJECTIVES: To describe the characteristics and outcomes of afebrile infants ≤60 days old with invasive bacterial infection (IBI). METHODS: We conducted a secondary analysis of a cross-sectional study of infants ≤60 days old with IBI prese…
View article: Febrile Infants ≤60 Days Old With Positive Urinalysis Results and Invasive Bacterial Infections
Febrile Infants ≤60 Days Old With Positive Urinalysis Results and Invasive Bacterial Infections Open
OBJECTIVES: We aimed to describe the clinical and laboratory characteristics of febrile infants ≤60 days old with positive urinalysis results and invasive bacterial infections (IBI). METHODS: We performed a planned secondary analysis of a …
View article: Height of fever and invasive bacterial infection
Height of fever and invasive bacterial infection Open
Objective We aimed to evaluate the association of height of fever with invasive bacterial infection (IBI) among febrile infants <=60 days of age. Methods In a secondary analysis of a multicentre case–control study of non-ill-appearing febr…
View article: A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection
A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection Open
OBJECTIVES: To derive and internally validate a prediction model for the identification of febrile infants ≤60 days old at low probability of invasive bacterial infection (IBI). METHODS: We conducted a case-control study of febrile infants…
View article: Risk Stratification of Febrile Infants ≤60 Days Old Without Routine Lumbar Puncture
Risk Stratification of Febrile Infants ≤60 Days Old Without Routine Lumbar Puncture Open
OBJECTIVES: To evaluate the Rochester and modified Philadelphia criteria for the risk stratification of febrile infants with invasive bacterial infection (IBI) who do not appear ill without routine cerebrospinal fluid (CSF) testing. METHOD…
View article: Management of the Febrile Young Infant
Management of the Febrile Young Infant Open
Infants aged 90 days or younger with fever are frequently evaluated in the pediatric emergency department. Physical examination findings and individual laboratory investigations are not reliable to differentiate benign viral infections fro…
View article: AKI in Children Hospitalized with Nephrotic Syndrome
AKI in Children Hospitalized with Nephrotic Syndrome Open
AKI is common in children hospitalized with nephrotic syndrome and should be deemed the third major complication of nephrotic syndrome in children in addition to infection and venous thromboembolism. Risk factors for AKI include steroid-re…