Christopher D. Witiw
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View article: Development and validation of a case identification algorithm for hand trauma patients using health administrative data and the epidemiology of hand trauma in a universal healthcare system.
Development and validation of a case identification algorithm for hand trauma patients using health administrative data and the epidemiology of hand trauma in a universal healthcare system. Open
Our algorithm enabled identification of hand trauma cases using health administrative data suitable for population-level surveillance and health services research, revealing a rising burden of hand trauma from 1993 to 2023. These findings …
View article: Cost-Utility Analysis of Ligament Reconstruction Tendon Interposition Versus Suture Suspension Arthroplasty for Thumb Osteoarthritis
Cost-Utility Analysis of Ligament Reconstruction Tendon Interposition Versus Suture Suspension Arthroplasty for Thumb Osteoarthritis Open
Background: Thumb carpometacarpal joint osteoarthritis (CMCJ OA) is a common degenerative condition that causes pain, stiffness, and disability, reducing quality of life. Surgery is a well-established treatment option when conservative man…
View article: Laminoplasty compared to laminectomy and fusion for degenerative cervical myelopathy: a cost-utility analysis
Laminoplasty compared to laminectomy and fusion for degenerative cervical myelopathy: a cost-utility analysis Open
Both LP and LF can be cost-effective for DCM. While the base-case favored LF, probabilistic sensitivity analysis revealed no clear cost-utility advantage with comparable NMBs. Economic considerations alone should not drive surgical decisio…
View article: Predicting outcomes after moderate and severe traumatic brain injury using artificial intelligence: a systematic review
Predicting outcomes after moderate and severe traumatic brain injury using artificial intelligence: a systematic review Open
Methodological standards of existing clinical AI research remain poorly characterized and may partially explain the implementation gap between model development and meaningful clinical translation. This systematic review aims to identify A…
View article: High performance with fewer labels using semi-weakly supervised learning for pulmonary embolism diagnosis
High performance with fewer labels using semi-weakly supervised learning for pulmonary embolism diagnosis Open
This study proposes a semi-weakly supervised learning approach for pulmonary embolism (PE) detection on CT pulmonary angiography (CTPA) to alleviate the resource-intensive burden of exhaustive medical image annotation. Attention-based CNN-…
View article: Canadian Association of Radiologists Central Nervous System Diagnostic Imaging Referral Guideline
Canadian Association of Radiologists Central Nervous System Diagnostic Imaging Referral Guideline Open
The Canadian Association of Radiologists (CAR) Central Nervous System Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurosurgery, and neurology, a patient advisor, and an epidemiologist/guidel…
View article: Risk factors and development of a predictive model for frailty in patients with heart failure
Risk factors and development of a predictive model for frailty in patients with heart failure Open
Fall history, advanced age, female sex, low hemoglobin levels, and diabetes are significant independent risk factors for frailty in HF patients. The nomogram prediction model demonstrated strong predictive performance, with high accuracy a…
View article: Canadian Association of Radiologists Spine Imaging Referral Guideline
Canadian Association of Radiologists Spine Imaging Referral Guideline Open
The Canadian Association of Radiologists (CAR) Spine Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurology, neurosurgery, physiatry, a patient advisor, and an epidemiologist/guideline method…
View article: Assessing the Performance of Models from the 2022 RSNA Cervical Spine Fracture Detection Competition at a Level I Trauma Center
Assessing the Performance of Models from the 2022 RSNA Cervical Spine Fracture Detection Competition at a Level I Trauma Center Open
Winning machine learning models from the RSNA 2022 Cervical Spine Fracture Detection competition demonstrated high performance on a large clinical test set of emergency department cervical spine CT scans from a level I trauma center.
View article: Traumatic Cervical Spinal Cord Injury and Income and Employment Status
Traumatic Cervical Spinal Cord Injury and Income and Employment Status Open
Importance Spinal cord injury (SCI) causes drastic changes to an individual’s physical health that may be associated with the ability to work. Objective To estimate the association of SCI with individual earnings and employment status usin…
View article: Vision Transformer–based Decision Support for Neurosurgical Intervention in Acute Traumatic Brain Injury: Automated Surgical Intervention Support Tool
Vision Transformer–based Decision Support for Neurosurgical Intervention in Acute Traumatic Brain Injury: Automated Surgical Intervention Support Tool Open
Purpose To develop an automated triage tool to predict neurosurgical intervention for patients with traumatic brain injury (TBI). Materials and Methods A provincial trauma registry was reviewed to retrospectively identify patients with TBI…
View article: Contemporary trends in the incidence and timing of spinal metastases: A population-based study
Contemporary trends in the incidence and timing of spinal metastases: A population-based study Open
Background Spinal metastases are a significant complication of advanced cancer. In this study, we assess temporal trends in the incidence and timing of spinal metastases and examine underlying patient demographics and primary cancer associ…
View article: Withdrawal of Life-Sustaining Treatment for Pediatric Patients With Severe Traumatic Brain Injury
Withdrawal of Life-Sustaining Treatment for Pediatric Patients With Severe Traumatic Brain Injury Open
Importance The decision to withdraw life-sustaining treatment for pediatric patients with severe traumatic brain injury (TBI) is challenging for clinicians and families with limited evidence quantifying existing practices. Given the lack o…
View article: Data Liberation and Crowdsourcing in Medical Research: The Intersection of Collective and Artificial Intelligence
Data Liberation and Crowdsourcing in Medical Research: The Intersection of Collective and Artificial Intelligence Open
In spite of an exponential increase in the volume of medical data produced globally, much of these data are inaccessible to those who might best use them to develop improved health care solutions through the application of advanced analyti…
View article: Risk factors for C5 palsy: a systematic review and multivariate analysis
Risk factors for C5 palsy: a systematic review and multivariate analysis Open
OBJECTIVE Postoperative C5 palsy (C5P) is a known complication in cervical spine surgery. However, its exact pathophysiology is unclear. The authors aimed to provide a review of the current understanding of C5P by performing a comprehensiv…
View article: Factors influencing withdrawal of life-supporting treatment in cervical spinal cord injury: a large multicenter observational cohort study
Factors influencing withdrawal of life-supporting treatment in cervical spinal cord injury: a large multicenter observational cohort study Open
Background Traumatic spinal cord injury (SCI) leads to profound neurologic sequelae, and the provision of life-supporting treatment serves great importance among this patient population. The decision for withdrawal of life-supporting treat…
View article: The RSNA Cervical Spine Fracture CT Dataset
The RSNA Cervical Spine Fracture CT Dataset Open
This dataset is composed of cervical spine CT images with annotations related to fractures; it is available at https://www.kaggle.com/competitions/rsna-2022-cervical-spine-fracture-detection/.
View article: Characterization of Spinal Cord Injury Patients for Arm Functional Restoration through Nerve Transfer
Characterization of Spinal Cord Injury Patients for Arm Functional Restoration through Nerve Transfer Open
Introduction: Traumatic spinal cord injuries (tSCI) are common, often leaving patients irreparably debilitated. Therefore, novel strategies such as nerve transfers (NT) are needed for mitigating secondary SCI damage and improving function.…
View article: A FIRST REPORT ON OUTCOMES OF STEREOTACTIC BODY RADIOTHERAPY FOR POSTERIOR ELEMENT ONLY SPINAL METASTASES AND VALIDATION OF RECOMMENDED CLINICAL TARGET VOLUME DELINEATION PRACTICE
A FIRST REPORT ON OUTCOMES OF STEREOTACTIC BODY RADIOTHERAPY FOR POSTERIOR ELEMENT ONLY SPINAL METASTASES AND VALIDATION OF RECOMMENDED CLINICAL TARGET VOLUME DELINEATION PRACTICE Open
Spine stereotactic body radiotherapy (SBRT) improves local control and pain response compared to conventional external beam radiotherapy. Consensus stipulates MRI-based delineation of the clinical target volume (CTV) and is based on spine …
View article: Assessment of the incremental prognostic value from the modified frailty index-5 in complete traumatic cervical spinal cord injury
Assessment of the incremental prognostic value from the modified frailty index-5 in complete traumatic cervical spinal cord injury Open
Frailty, as measured by the modified frailty index-5 (mFI-5), and older age are associated with increased mortality in the setting of spinal cord injury (SCI). However, there is limited evidence demonstrating an incremental prognostic valu…
View article: Multicenter retrospective cohort study of the association between surgery for odontoid fractures in the elderly and in-hospital outcomes
Multicenter retrospective cohort study of the association between surgery for odontoid fractures in the elderly and in-hospital outcomes Open
Odontoid fractures are increasingly prevalent in older adults and associated with high morbidity and mortality. Optimal management remains controversial. Our study aims to investigate the association between surgical management of odontoid…
View article: Association between Surgery for Odontoid Fractures in the Elderly and in-hospital Outcomes: Analysis from the American College of Surgeons Trauma Quality Improvement Program
Association between Surgery for Odontoid Fractures in the Elderly and in-hospital Outcomes: Analysis from the American College of Surgeons Trauma Quality Improvement Program Open
Odontoid fractures are increasingly prevalent in older adults and associated with high morbidity and mortality. Optimal management remains controversial. Our study aims to investigate the association between surgical management of odontoid…
View article: Comparison of Age and Modified Frailty Index-5 as Predictors of In-Hospital Mortality in Complete Traumatic Cervical Spinal Cord Injury
Comparison of Age and Modified Frailty Index-5 as Predictors of In-Hospital Mortality in Complete Traumatic Cervical Spinal Cord Injury Open
Frailty, as measured by the modified frailty index-5 (mFI-5), and older age are associated with increased mortality in the setting of spinal cord injury (SCI). However, a comparison of the predictive power of each measure has not been comp…
View article: Mature Local Control and Reirradiation Rates Comparing Spine Stereotactic Body Radiation Therapy With Conventional Palliative External Beam Radiation Therapy
Mature Local Control and Reirradiation Rates Comparing Spine Stereotactic Body Radiation Therapy With Conventional Palliative External Beam Radiation Therapy Open
Risk of local failure and reirradiation is lower with SBRT compared with cEBRT for spinal metastases. Although the iatrogenic vertebral compression fracture rates were within expectations, grade 3 vertebral compression fractures were isola…
View article: Calcium pyrophosphate dihydrate crystal deposition disease and retro-odontoid pseudotumor rupture managed via posterior occipital cervical instrumented fusion: illustrative case
Calcium pyrophosphate dihydrate crystal deposition disease and retro-odontoid pseudotumor rupture managed via posterior occipital cervical instrumented fusion: illustrative case Open
BACKGROUND Craniocervical junction and subaxial cervical spinal manifestations of calcium pyrophosphate deposition disease are rarely encountered. The authors presented a severe case of retro-odontoid pseudotumor rupture causing rapid quad…
View article: Establishing the Socio-Economic Impact of Degenerative Cervical Myelopathy Is Fundamental to Improving Outcomes [AO Spine RECODE-DCM Research Priority Number 8]
Establishing the Socio-Economic Impact of Degenerative Cervical Myelopathy Is Fundamental to Improving Outcomes [AO Spine RECODE-DCM Research Priority Number 8] Open
Study Design: Literature Review (Narrative). Objective: To contextualize AO Spine RECODE-DCM research priority number 5: What is the socio-economic impact of DCM? (The financial impact of living with DCM to the individual, their supporters…
View article: Association of Venous Thromboembolism Prophylaxis After Neurosurgical Intervention for Traumatic Brain Injury With Thromboembolic Complications, Repeated Neurosurgery, and Mortality
Association of Venous Thromboembolism Prophylaxis After Neurosurgical Intervention for Traumatic Brain Injury With Thromboembolic Complications, Repeated Neurosurgery, and Mortality Open
In this cohort study of patients who underwent urgent neurosurgical interventions for TBI, early pharmacologic VTE prophylaxis was associated with reduced risk of thromboembolism. However, earlier initiation of prophylaxis was associated w…