Chryslain Sumian
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View article: In vitro quality of whole blood‐derived red cell concentrates collected, processed and stored in a blood bag set plasticized with di (2‐ethylhexyl) terephthalate
In vitro quality of whole blood‐derived red cell concentrates collected, processed and stored in a blood bag set plasticized with di (2‐ethylhexyl) terephthalate Open
Background and Objectives Due to toxicity concerns, di(2‐ethylhexyl) phthalate (DEHP)—the most used plasticizer in polyvinyl chloride (PVC) whole blood (WB) collection and processing bag sets—will be effectively prohibited in medical devic…
View article: Inactivation of <scp>SARS‐CoV</scp>‐2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light
Inactivation of <span>SARS‐CoV</span>‐2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light Open
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is unlikely to be a major transfusion‐transmitted pathogen; however, convalescent plasma is a treatment option used in some regions. The risk of transfusion‐transmitte…
View article: Pathogen reduction through additive-free short-wave UV light irradiation retains the optimal efficacy of human platelet lysate for the expansion of human bone marrow mesenchymal stem cells
Pathogen reduction through additive-free short-wave UV light irradiation retains the optimal efficacy of human platelet lysate for the expansion of human bone marrow mesenchymal stem cells Open
We demonstrated the feasibility of using UV-C-treated platelets to subsequently obtain pathogen-reduced hPL, while preserving its optimal quality and efficacy for hMSC expansion in cell therapy applications.
View article: Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light
Reduction of Zika virus infectivity in platelet concentrates after treatment with ultraviolet C light and in plasma after treatment with methylene blue and visible light Open
BACKGROUND Zika virus (ZIKV) has emerged as a potential threat to transfusion safety worldwide. Pathogen inactivation is one approach to manage this risk. In this study, the efficacy of the THERAFLEX UV‐Platelets system and THERAFLEX MB‐Pl…
View article: In vitro Quality of Platelets with Low Plasma Carryover Treated with Ultraviolet C Light for Pathogen Inactivation
In vitro Quality of Platelets with Low Plasma Carryover Treated with Ultraviolet C Light for Pathogen Inactivation Open
Background: The THERAFLEX UV-Platelets system uses shortwave ultraviolet C light (UVC, 254 nm) to inactivate pathogens in platelet components. Plasma carryover influences pathogen inactivation and platelet quality following treatment. The …