Chuanfu Dong
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View article: Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis Open
Scale drop disease virus (SDDV), a distinct member of the genus Megalocytivirus within the Iridoviridae family, has emerged as a novel threat to global teleost aquaculture. Despite its importance, the pathogenic mechanism of SDDV remains l…
View article: Detection and Genomic Characterisation of Scale Drop Disease Virus (SDDV) in Farmed Yellowfin Seabream ( <i>Acanthopagrus latus</i> ) in Southern China
Detection and Genomic Characterisation of Scale Drop Disease Virus (SDDV) in Farmed Yellowfin Seabream ( <i>Acanthopagrus latus</i> ) in Southern China Open
Scale drop disease virus (SDDV) is a distinct member of the genus Megalocytivirus within the family Iridoviridae , which was recently identified as a causative agent of yellowfin seabream Acanthopagrus latus ascitic diseases (YFSBAD). Here…
View article: Dissection of the global responses of mandarin fish pyloric cecum to an acute ranavirus (MRV) infection reveals the formation of serositis and then ascites
Dissection of the global responses of mandarin fish pyloric cecum to an acute ranavirus (MRV) infection reveals the formation of serositis and then ascites Open
Mandarin fish ranavirus (MRV), a new member of the species Ranavirus micropterus1 , sharing over 98% whole-genome nucleotide identity with the well-known largemouth bass virus (LMBV), is a distinct member of the genus Ranavirus within the …
View article: Vitamin C Inhibits Scale Drop Disease Virus Infectivity by Targeting Nrf2 to Reduce Ferroptosis
Vitamin C Inhibits Scale Drop Disease Virus Infectivity by Targeting Nrf2 to Reduce Ferroptosis Open
Scale drop disease virus (SDDV) poses an escalating threat to global aquaculture, prompting an urgent need for research. Our study found that SDDV infection upregulates genes related to iron, oxidative stress, and lipid metabolism, causing…
View article: Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade host cell via clathrin-mediated endocytosis
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade host cell via clathrin-mediated endocytosis Open
Scale drop disease virus (SDDV), a distinct member of the genus Megalocytivirus within the Iridoviridae family, has emerged as a novel threat to global teleost aquaculture. Despite its importance, the pathogenic mechanism of SDDV remains l…
View article: Scale drop disease virus (SDDV) triggering ferroptosis both <i>in vivo</i> and <i>in vitro</i> facilitates virus infection via targeting transferrin receptor 1 (TfR1)
Scale drop disease virus (SDDV) triggering ferroptosis both <i>in vivo</i> and <i>in vitro</i> facilitates virus infection via targeting transferrin receptor 1 (TfR1) Open
Scale drop disease virus (SDDV) is a distinct member in genus Megalocytivirus of family Iridoviridae , garnering increasing attention due to its significant threat to teleost. Ferroptosis is a new type of cell death discovered recently and…
View article: Dissection of the Global Responses of Mandarin Fish Pyloric Caecum to An Acute Ranavirus (MRV) Infection Reveals the Formation of Serositis and Then Ascites
Dissection of the Global Responses of Mandarin Fish Pyloric Caecum to An Acute Ranavirus (MRV) Infection Reveals the Formation of Serositis and Then Ascites Open
Mandarin fish ranavirus (MRV), a variant of largemouth bass virus (LMBV), is a distinct member of the genus Ranavirus within the family Iridoviridae . Acute MRV infection predominantly affects the pyloric caecum, a critical visceral organ …
View article: Peripheral B Lymphocyte Serves as a Reservoir for the Persistently Covert Infection of Mandarin Fish Siniperca chuatsi Ranavirus
Peripheral B Lymphocyte Serves as a Reservoir for the Persistently Covert Infection of Mandarin Fish Siniperca chuatsi Ranavirus Open
Mandarin fish ranavirus (MRV) is a distinctive member among the genus Ranavirus of the family Iridoviridae. The persistently covert infection of MRV was previously observed in a natural outbreak of MRV, but the underlying mechanism remains…
View article: The Co-infection of ISKNV-II and RGNNV Resulting in Mass Mortalities of Juvenile Asian Seabass (Lates calcarifer), Zhuhai, Southern China
The Co-infection of ISKNV-II and RGNNV Resulting in Mass Mortalities of Juvenile Asian Seabass (Lates calcarifer), Zhuhai, Southern China Open
A mass mortality event of Asian seabass Lates calcarifer juveniles occurred in Zhuhai, the main Asian seabass cultured area in mainland China. The fish samples were pooled for pathogen identification and both high viral loads of ISKNV and …
View article: Peripheral B Lymphocyte Serves as A Reservoir for The Persistently Covert Infection of Mandarinfish<i>Siniperca chuatsi</i>Ranavirus
Peripheral B Lymphocyte Serves as A Reservoir for The Persistently Covert Infection of Mandarinfish<i>Siniperca chuatsi</i>Ranavirus Open
Genus Ranavirus in family Iridoviridae is composed of large members with various genomic sizes and viral gene contents, infecting a variety of ectothermic vertebrates including reptile, amphibians and bony fish worldwide. Mandarinfish rana…
View article: Ferroptosis and iron mineralization involved in the death and survival of orange‐spotted groupers challenged with <i>Pseudomonas plecoglossicida</i>
Ferroptosis and iron mineralization involved in the death and survival of orange‐spotted groupers challenged with <i>Pseudomonas plecoglossicida</i> Open
Pseudomonas plecoglossicida ( P. plecoglossicida ) is a pathogen in aquaculture that causes considerable economic loss. According to artificial infection experiments, the fish were classified into control group, moribund group, and surviva…
View article: Generation and Characterization of ORF55/ORF57-Deleted Recombinant Cyprinid herpesvirus 2 Mutants with Chimeric Capsid Protein Gene of Grouper Nervous Necrosis Virus
Generation and Characterization of ORF55/ORF57-Deleted Recombinant Cyprinid herpesvirus 2 Mutants with Chimeric Capsid Protein Gene of Grouper Nervous Necrosis Virus Open
Cyprinid herpesvirus 2 (CyHV-2) is a pathogen that causes significant losses to the global aquaculture industry due to mass mortality in crucian carp and goldfish. This study demonstrates that the ORF55/ORF57 deletion mutants CyHV-2-Δ55-CP…
View article: The Inactivated ISKNV-I Vaccine Confers Highly Effective Cross-Protection against Epidemic RSIV-I and RSIV-II from Cultured Spotted Sea Bass Lateolabrax maculatus
The Inactivated ISKNV-I Vaccine Confers Highly Effective Cross-Protection against Epidemic RSIV-I and RSIV-II from Cultured Spotted Sea Bass Lateolabrax maculatus Open
Red seabream iridovirus (RSIV) infects a wide mariculture bony fish and has resulted in significant annual economic loss worldwide. Previous studies showed that the phenotypic diversity of infectious RSIV isolates would lead to different v…
View article: Scale Drop Disease Virus Associated Yellowfin Seabream (Acanthopagrus latus) Ascites Diseases, Zhuhai, Guangdong, Southern China: The First Description
Scale Drop Disease Virus Associated Yellowfin Seabream (Acanthopagrus latus) Ascites Diseases, Zhuhai, Guangdong, Southern China: The First Description Open
Scale drop disease virus (SDDV), an emerging piscine iridovirus prevalent in farmed Asian seabass Lates calcarifer in Southeast Asia, was firstly scientifically descripted in Singapore in 2015. Here, an SDDV isolate ZH-06/20 was isolated b…
View article: Ion Torrent next-generation sequencing reveals the complete mitochondrial genome of koi carp (<i>Cyprinus carpio</i>, Cyprinidae)
Ion Torrent next-generation sequencing reveals the complete mitochondrial genome of koi carp (<i>Cyprinus carpio</i>, Cyprinidae) Open
The complete mitochondrial genome of the koi carp (Cyprinus carpio, Cyprinidae) was sequenced in the present study by using Ion Torrent Personal Genome Machine (PGM) platform for the first time. The mitochondrial genome sequence is 16 581 …