2025-05-17
Lifetime co-exposure of parental zebrafish to benzophenone-3 and titanium dioxide nanoparticles leads to developmental neurotoxicity and thyroid endocrine disruption in their offspring
2025-05-17 • Linxuan Tian, Chun-Lan Dai, E.-F. Feng, Qinyuan Yang, Yao Jiang, Yubo Liu, Yanni Wang, Junyan Tao
Benzophenone-3 (BP3) is a prevalent environmental UV filter widely used in personal care products, and titanium dioxide nanoparticles (nano-TiO₂), another commonly applied material in consumer goods and industrial applications, may coexist with BP3 in environmental media. This study investigates the potential parental transfer of BP3 and transgenerational effects on development and thyroid hormone homeostasis in F1 larvae following lifetime parental exposure to BP3 and nano-TiO<sub>2</sub>. Zebrafish embryos were …