Chun Wang
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View article: Predicting preoperative lymph node metastasis in patients with high-grade serous ovarian cancer by using intratumoral and peritumoral radiomics: a retrospective cohort study
Predicting preoperative lymph node metastasis in patients with high-grade serous ovarian cancer by using intratumoral and peritumoral radiomics: a retrospective cohort study Open
View article: Predicting preoperative lymph node metastasis in patients with high-grade serous ovarian cancer by using intratumoral and peritumoral radiomics: A retrospective cohort study
Predicting preoperative lymph node metastasis in patients with high-grade serous ovarian cancer by using intratumoral and peritumoral radiomics: A retrospective cohort study Open
Background Ovarian cancer (OC) carries the worst prognosis among gynecologic cancers, with high-grade serous ovarian cancer (HGSOC) as its most common subtype. Cytoreductive surgery (tumor resection), such as lymphadenectomy, is the corner…
View article: Plasma metabolomics of Mycoplasma synoviae infection in SPF White Leghorn hens by liquid chromatography-tandem mass spectrometry
Plasma metabolomics of Mycoplasma synoviae infection in SPF White Leghorn hens by liquid chromatography-tandem mass spectrometry Open
View article: Enzymatically responsive nanocarriers targeting PD-1 and TGF-β pathways reverse immunotherapeutic resistance and elicit robust therapeutic efficacy
Enzymatically responsive nanocarriers targeting PD-1 and TGF-β pathways reverse immunotherapeutic resistance and elicit robust therapeutic efficacy Open
View article: Whole-genome sequencing resolves biochemical misidentification of <i>Neisseria</i> species from urogenital specimens
Whole-genome sequencing resolves biochemical misidentification of <i>Neisseria</i> species from urogenital specimens Open
Neisseria meningitidis (Nm) and Neisseria gonorrhoeae (Ng) are human pathogens that sometimes occupy the same anatomical niche. Ng, the causative agent of gonorrhea, infects 87 million individuals annually worldwide and is an urgent threat…
View article: MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder
MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder Open
Background Increasing evidence supports the role of microRNAs (miRNAs) in major depressive disorder (MDD), but the pathophysiological mechanism remains elusive. Aims To explore the mechanism of microRNA-451a (miR-451a) in the pathology and…
View article: Polymer–Protein Nanovaccine Synthesized via Reactive Self‐Assembly with Potential Application in Cancer Immunotherapy: Physicochemical and Biological Characterization In Vitro and In Vivo
Polymer–Protein Nanovaccine Synthesized via Reactive Self‐Assembly with Potential Application in Cancer Immunotherapy: Physicochemical and Biological Characterization In Vitro and In Vivo Open
Nanovaccines composed of polymeric nanocarriers and protein‐based antigens have attracted much attention in recent years because of their enormous potential in the prevention and treatment of diseases such as viral infections and cancer. W…
View article: ApoE Mimetic Peptide COG1410 Exhibits Strong Additive Interaction with Antibiotics Against Mycobacterium smegmatis
ApoE Mimetic Peptide COG1410 Exhibits Strong Additive Interaction with Antibiotics Against Mycobacterium smegmatis Open
COG1410 was a novel and potent AMP against M. smegmatis by disrupting the integrity of cell membrane.
View article: Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor
Prenatal stress modulates HPA axis homeostasis of offspring through dentate TERT independently of glucocorticoids receptor Open
View article: Identification and antibiotic susceptibility evaluation of Mycoplasma synoviae isolated from chickens in central China
Identification and antibiotic susceptibility evaluation of Mycoplasma synoviae isolated from chickens in central China Open
Mycoplasma synoviae ( M. synoviae ) infections have become an increasingly serious concern in China because they cause huge economic losses to the poultry industry. Antibiotic treatment is one of control strategies that can be used to cont…
View article: Reliability of TMS measurements using conventional hand-hold method with different numbers of stimuli for tibialis anterior muscle in healthy adults
Reliability of TMS measurements using conventional hand-hold method with different numbers of stimuli for tibialis anterior muscle in healthy adults Open
Objective: The objective of this study was to determine the reliability of corticomotor excitability measurements using the conventional hand-hold transcranial magnetic stimulation (TMS) method for the tibialis anterior (TA) muscle in heal…
View article: Panic disorder aging characteristics: The role of telomerase reverse transcriptase gene and brain function
Panic disorder aging characteristics: The role of telomerase reverse transcriptase gene and brain function Open
Panic disorder (PD) causes serious functional damage and disability and accelerates the process of individual aging. The pathological basis of PD is the same as that of age-related diseases, which is proposed as a new viewpoint in recent y…
View article: Correction: Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation
Correction: Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation Open
Following publication of the original article [1], the authors regretted to find misinterpretation of data in Fig. 5e, f and Fig. S8b-d.These plots actually showed pseudotime gene expression analysis in the whole bone marrow cells in KO an…
View article: Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation
Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation Open
View article: Clinical effects of continuous theta burst stimulation for generalized anxiety disorder and a mechanism involving α oscillations: a randomized controlled trial
Clinical effects of continuous theta burst stimulation for generalized anxiety disorder and a mechanism involving α oscillations: a randomized controlled trial Open
Background Continuous theta burst stimulation (cTBS) is a much more rapid protocol than low-frequency repetitive transcranial magnetic stimulation (rTMS), but no clinical trial has yet investigated the efficacy and mechanisms of cTBS for t…
View article: A novel missense creatine mutant of CaBP4, c.464G>A (p.G155D), associated with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), reduces the expression of CaBP4
A novel missense creatine mutant of CaBP4, c.464G>A (p.G155D), associated with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), reduces the expression of CaBP4 Open
These results reveal that c.464G>A (p.G155D) in CaBP4 reduced the expression of CaBP4 by reducing the stability of the CaBP4 protein. Mutations in the CaBP4 gene may be associated with ADNFLE.
View article: Motor Imagination of Lower Limb Movements at Different Frequencies
Motor Imagination of Lower Limb Movements at Different Frequencies Open
Motor imagination (MI) is the mental process of only imagining an action without an actual movement. Research on MI has made significant progress in feature information detection and machine learning decoding algorithms, but there are stil…
View article: Nitric Oxide Synthase Type 1 Methylation Is Associated With White Matter Microstructure in the Corpus Callosum and Greater Panic Disorder Severity Among Panic Disorder Patients
Nitric Oxide Synthase Type 1 Methylation Is Associated With White Matter Microstructure in the Corpus Callosum and Greater Panic Disorder Severity Among Panic Disorder Patients Open
Objectives: Methylation of the neuronal nitric oxide synthase ( NOS1 / nNOS ) gene has recently been identified as a promising biomarker of psychiatric disorders. NOS1 plays an essential role in neurite outgrowth and may thus affect the mi…
View article: Modular Integration of Hydrogel Neural Interfaces
Modular Integration of Hydrogel Neural Interfaces Open
Thermal drawing has been recently leveraged to yield multifunctional, fiber-based neural probes at near kilometer length scales. Despite its promise, the widespread adoption of this approach has been impeded by (1) material compatibility r…
View article: Disrupted fronto-temporal function in panic disorder: a resting-state connectome study
Disrupted fronto-temporal function in panic disorder: a resting-state connectome study Open
Recent neuroimaging studies have identified altered activations and connectivity among many brain regions as potential biomarkers for panic disorder. However, little was known about how topological properties would change in panic disorder…
View article: Abnormalities of intrinsic brain activity in chronic primary insomnia: a protocol for systematic review and meta-analysis of resting-state functional imaging
Abnormalities of intrinsic brain activity in chronic primary insomnia: a protocol for systematic review and meta-analysis of resting-state functional imaging Open
Review question / Objective: Studies of abnormal regional homogeneity (ReHo) in insomnia have reported inconsistent results.The objective of this protocol is to conducted a metaanalysis using the Seed-based d Mapping software package to id…
View article: Combination of irreversible electroporation with sustained release of a synthetic membranolytic polymer for enhanced cancer cell killing
Combination of irreversible electroporation with sustained release of a synthetic membranolytic polymer for enhanced cancer cell killing Open
View article: Modular Integration of Hydrogel Neural Interfaces
Modular Integration of Hydrogel Neural Interfaces Open
Thermal drawing has been recently leveraged to yield multi-functional, fiber-based neural probes at near kilometer length scales. Despite its promise, the widespread adoption of this approach has been impeded by (1) material compatibility …
View article: Modular Integration of Hydrogel Neural Interfaces
Modular Integration of Hydrogel Neural Interfaces Open
Thermal drawing has been recently leveraged to yield multi-functional, fiber-based neural probes at near kilometer length scales. Despite its promise, the widespread adoption of this approach has been impeded by (1) material compatibility …
View article: Abnormalities of intrinsic brain activity in irritable bowel syndrome (IBS): a protocol for systematic review and meta-analysis of resting-state functional imaging
Abnormalities of intrinsic brain activity in irritable bowel syndrome (IBS): a protocol for systematic review and meta-analysis of resting-state functional imaging Open
Review question / Objective: Studies of abnormal regional homogeneity (ReHo) in irritable bowel syndrome (IBS) have reported inconsistent results.Therefore, we conducted a meta-analysis using the Seed-based d Mapping software package to id…
View article: Modulation of the Corticomotor Excitability by Repetitive Peripheral Magnetic Stimulation on the Median Nerve in Healthy Subjects
Modulation of the Corticomotor Excitability by Repetitive Peripheral Magnetic Stimulation on the Median Nerve in Healthy Subjects Open
Objective: We aimed to examine the effects of repetitive peripheral nerve magnetic stimulation (rPNMS) on the excitability of the contralateral motor cortex and motor function of the upper limb in healthy subjects. Methods: Forty-six healt…
View article: Dexamethasone does not ameliorate gliosis in a mouse model of neurodegenerative disease
Dexamethasone does not ameliorate gliosis in a mouse model of neurodegenerative disease Open
View article: Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data
Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance data Open
View article: Inflammation and Endothelial Function Relevant Genetic Polymorphisms and Carotid Plaque in Chinese Population
Inflammation and Endothelial Function Relevant Genetic Polymorphisms and Carotid Plaque in Chinese Population Open
Aim: To examine the association between carotid plaque and variants in genes involved in inflammation and endothelial function. Methods: This was a multicenter, cross-sectional survey in southwestern China. The residents aged ≥ 40 years vo…
View article: Functional Impairment Related Aging in Panic Disorder: The Role of Telomerase Reverse Transcriptase Gene and Brain Function
Functional Impairment Related Aging in Panic Disorder: The Role of Telomerase Reverse Transcriptase Gene and Brain Function Open