Chun‐Dong Xue
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View article: A Variable Cross-Section Microfluidic Channel for Simultaneous Reproduction of Low Oscillatory and Pulsatile Wall Shear Stress at the Carotid Bifurcation: A Computational Fluid Dynamics-Based Study
A Variable Cross-Section Microfluidic Channel for Simultaneous Reproduction of Low Oscillatory and Pulsatile Wall Shear Stress at the Carotid Bifurcation: A Computational Fluid Dynamics-Based Study Open
Pulsatile blood flow generates complex wall shear stress (WSS) patterns at the carotid bifurcation, which critically regulate endothelial function and structure. While physiological pulsatile WSS (PWSS) is essential for maintaining vascula…
View article: Effects of resistance exercise intensity on cerebral blood flow and cerebrovascular reactivity in healthy young males: A pilot study
Effects of resistance exercise intensity on cerebral blood flow and cerebrovascular reactivity in healthy young males: A pilot study Open
Exercise intensity has been shown to elicit different cerebral blood flow velocity (CBFv) responses. This study aimed to compare the acute effects of resistance exercise at different intensities on hemodynamics and cerebrovascular reactivi…
View article: Adjusting blood redistribution to suppress flow disturbances of hemodialysis arteriovenous fistula: a computational fluid dynamics analysis
Adjusting blood redistribution to suppress flow disturbances of hemodialysis arteriovenous fistula: a computational fluid dynamics analysis Open
Introduction The dramatic hemodynamic disturbances induced by arteriovenous fistula (AVF) creation are universally acknowledged as the triggering factors for AVF dysfunction. The postoperative blood redistribution is greatly relevant with …
View article: Microfluidic investigation for shear-stress-mediated repair of dysglycemia-induced endothelial cell damage
Microfluidic investigation for shear-stress-mediated repair of dysglycemia-induced endothelial cell damage Open
Dysglycemia causes arterial endothelial damage, which is an early critical event in vascular complications for diabetes patients. Physiologically, moderate shear stress (SS) helps maintain endothelial cell health and normal function. React…
View article: Multiplex vortex instability in the flow of non-Newtonian fluids through microcavity arrays
Multiplex vortex instability in the flow of non-Newtonian fluids through microcavity arrays Open
Complex fluids always possess obvious non-Newtonian properties that facilitate the occurrence and development of vortex instability in porous media, which is of critical significance in many natural and industrial processes. It is widely k…
View article: Effects of accumulated exercise on the stiffness and hemodynamics of the common carotid artery
Effects of accumulated exercise on the stiffness and hemodynamics of the common carotid artery Open
Purpose: This research aims to study and compare the effects of moderate-intensity continuous exercise and accumulated exercise with different number of bouts on common carotid arterial stiffness and hemodynamic variables. Methods: Thirty …
View article: Microfluidic Channel for Simulating Wall Shear Stress Waveforms in Carotid Bifurcation Blood Flow
Microfluidic Channel for Simulating Wall Shear Stress Waveforms in Carotid Bifurcation Blood Flow Open
Wall Shear Stress (WSS) abnormalities in carotid artery blood flow are key hemodynamic factors leading to arterial endothelial damage, atherosclerotic plaque formation, and carotid artery stenosis. Precise simulation of carotid artery bloo…
View article: Instabilities of Marangoni and Elasticity in a Melting Polymer Film
Instabilities of Marangoni and Elasticity in a Melting Polymer Film Open
View article: Hemodynamics of Ventricular-Arterial Coupling Under Enhanced External Counterpulsation: An Optimized Dual-Source Lumped Parameter Model
Hemodynamics of Ventricular-Arterial Coupling Under Enhanced External Counterpulsation: An Optimized Dual-Source Lumped Parameter Model Open
View article: Effect of the uronic acid composition of alginate in alginate/collagen hybrid hydrogel on chondrocyte behavior
Effect of the uronic acid composition of alginate in alginate/collagen hybrid hydrogel on chondrocyte behavior Open
Introduction: Developing a culture system that can effectively maintain chondrocyte phenotype and functionalization is a promising strategy for cartilage repair. Methods: An alginate/collagen (ALG/COL) hybrid hydrogel using different gulur…
View article: An Integrated Model for Intracellular NO and ROS Dynamics in Vascular Endothelial Cells Activated by Exercise-Induced Wall Shear Stress
An Integrated Model for Intracellular NO and ROS Dynamics in Vascular Endothelial Cells Activated by Exercise-Induced Wall Shear Stress Open
View article: Hopping Behavior Mediates the Anomalous Confined Diffusion of Nanoparticles in Porous Hydrogels
Hopping Behavior Mediates the Anomalous Confined Diffusion of Nanoparticles in Porous Hydrogels Open
Diffusion is an essential means of mass transport in porous materials such as hydrogels, which are appealing in various biomedical applications. Herein, we investigate the diffusive motion of nanoparticles (NPs) in porous hydrogels to prov…
View article: Deep-learning Assisted Extraction of Fluid Velocity from Scalar Signal Transport in a Shallow Microfluidic Channel
Deep-learning Assisted Extraction of Fluid Velocity from Scalar Signal Transport in a Shallow Microfluidic Channel Open
Precise measurement of flow velocity in microfluidic channels is of importance in microfluidic applications, such as quantitative chemical analysis, sample preparation and drug synthesis. However, simple approaches for quickly and precisel…
View article: Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization
Raman Spectroscopic Characterization of Polymerization Kinetics of Cyanoacrylate Embolic Glues for Vascular Embolization Open
Endovascular glue embolization is a minimally invasive technique used to selectively reduce or block the blood supply to specific targeted vessels. Cyanoacrylate glues, mixed with radiopaque iodized oil, have been widely used for vascular …
View article: Modeling of Endothelial Calcium Responses within a Microfluidic Generator of Spatio-Temporal ATP and Shear Stress Signals
Modeling of Endothelial Calcium Responses within a Microfluidic Generator of Spatio-Temporal ATP and Shear Stress Signals Open
Intracellular calcium dynamics play essential roles in the proper functioning of cellular activities. It is a well known important chemosensing and mechanosensing process regulated by the spatio-temporal microenvironment. Nevertheless, how…
View article: Effect of Fe2O3 and CeO2 on Transmittance of Y2O3 Stabilized Tetragonal Zirconia Polycrystals
Effect of Fe2O3 and CeO2 on Transmittance of Y2O3 Stabilized Tetragonal Zirconia Polycrystals Open
The present study is to investigate the effect of metal oxides Fe 2 O 3 and CeO 2 on the structural and optical characteristics of Y 2 O 3 stabilized tetragonal zirconia ceramic (Y-TZP). Different concentrations of Fe 2 O 3 and CeO 2 are a…
View article: Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device
Breakup Dynamics of Semi-dilute Polymer Solutions in a Microfluidic Flow-focusing Device Open
Droplet microfluidics involving non-Newtonian fluids is of great importance in both fundamental mechanisms and practical applications. In the present study, breakup dynamics in droplet generation of semi-dilute polymer solutions in a micro…
View article: Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions
Diffusion of Nanoparticles with Activated Hopping in Crowded Polymer Solutions Open
A long-distance hop of diffusive nanoparticles (NPs) in crowded environments was commonly considered unlikely, and its characteristics remain unclear. In this work, we experimentally identify the occurrence of the intermittent hops of larg…
View article: Confinements regulate capillary instabilities of fluid threads – CORRIGENDUM
Confinements regulate capillary instabilities of fluid threads – CORRIGENDUM Open
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View article: A Capillary-Evaporation Micropump for Real-Time Sweat Rate Monitoring with an Electrochemical Sensor
A Capillary-Evaporation Micropump for Real-Time Sweat Rate Monitoring with an Electrochemical Sensor Open
Sweat collection and real time monitoring of sweat rate play essential roles in physiology monitoring and assessment of an athlete’s performance during exercise. In this paper, we report a micropump for sweat simulant collection based on t…
View article: A Microfluidic Micropipette Aspiration Device to Study Single-Cell Mechanics Inspired by the Principle of Wheatstone Bridge
A Microfluidic Micropipette Aspiration Device to Study Single-Cell Mechanics Inspired by the Principle of Wheatstone Bridge Open
The biomechanical properties of single cells show great potential for early disease diagnosis and effective treatments. In this study, a microfluidic device was developed for quantifying the mechanical properties of a single cell. Micropip…
View article: Tunable structures of compound droplets formed by collision of immiscible microdroplets
Tunable structures of compound droplets formed by collision of immiscible microdroplets Open
View article: Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning
Sheathless Focusing and Separation of Diverse Nanoparticles in Viscoelastic Solutions with Minimized Shear Thinning Open
Viscoelastic microfluidics becomes an efficient and label-free hydrodynamic technology to enrich and separate micrometer-scale particles, including blood cells, circulating tumor cells, and bacteria. However, the manipulation of nanoscale …
View article: Lateral migration of dual droplet trains in a double spiral microchannel
Lateral migration of dual droplet trains in a double spiral microchannel Open
View article: Probing Non-Gaussianity in Confined Diffusion of Nanoparticles
Probing Non-Gaussianity in Confined Diffusion of Nanoparticles Open
Confined diffusion is ubiquitous in nature. Ever since the "anomalous yet Brownian" motion was observed, the non-Gaussianity in confined diffusion has been unveiled as an important issue. In this Letter, we experimentally investigate the c…
View article: A generalized formula for inertial lift on a sphere in microchannels
A generalized formula for inertial lift on a sphere in microchannels Open
We propose a fitting formula for the inertial lift on a sphere drawn from direct numerical simulation data obtained in straight microchannels. The formula consists of four terms that represent the shear-gradient-induced lift, the wall-indu…
View article: Size-Based Separation of Particles and Cells Utilizing Viscoelastic Effects in Straight Microchannels
Size-Based Separation of Particles and Cells Utilizing Viscoelastic Effects in Straight Microchannels Open
Viscoelasticity-induced particle migration has recently received increasing attention due to its ability to obtain high-quality focusing over a wide range of flow rates. However, its application is limited to low throughput regime since th…
View article: Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels
Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels Open
View article: On the Successful Encapsulation of Water Droplets into Oil Droplets
On the Successful Encapsulation of Water Droplets into Oil Droplets Open