Chunfeng Lu
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View article: MLKL as an emerging machinery for modulating organelle dynamics: regulatory mechanisms, pathophysiological significance, and targeted therapeutics
MLKL as an emerging machinery for modulating organelle dynamics: regulatory mechanisms, pathophysiological significance, and targeted therapeutics Open
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase featured by a protein kinase-like domain without catalytic activity. MLKL was originally discovered to be phosphorylated by receptor-interacting protein kinase 1/3, typicall…
View article: Stromal Cell Derived Factor‐1 Promotes Hepatic Insulin Resistance via Inhibiting Hepatocyte Lipophagy
Stromal Cell Derived Factor‐1 Promotes Hepatic Insulin Resistance via Inhibiting Hepatocyte Lipophagy Open
Saturated fatty acid (SFA) accumulation in liver decreases hepatocyte lipophagy, a type of selective autophagy that degrades intracellular lipid droplets, leading to hepatic insulin resistance (IR), which contributes to simultaneous increa…
View article: Association between triglyceride glucose body mass index and left ventricular systolic synchronicity in patients with type 2 diabetes
Association between triglyceride glucose body mass index and left ventricular systolic synchronicity in patients with type 2 diabetes Open
Background: The triglyceride glucose-body mass index (TyG-BMI) is considered to be an alternative indicator of insulin resistance (IR) with greater clinical value in terms of cardiovascular risk. However, the relationship between TyG-BMI a…
View article: The bidirectional associations between sarcopenia-related traits and cognitive performance
The bidirectional associations between sarcopenia-related traits and cognitive performance Open
While many studies have sought to explore the degree to which sarcopenia-related traits are associated with cognitive performance, these studies have yielded contradictory results without any clear indication of the causality of such relat…
View article: A late eating midpoint is associated with increased risk of diabetic kidney disease: a cross-sectional study based on NHANES 2013–2020
A late eating midpoint is associated with increased risk of diabetic kidney disease: a cross-sectional study based on NHANES 2013–2020 Open
Background Modifying diet is crucial for diabetes and complication management. Numerous studies have shown that adjusting eating habits to align with the circadian rhythm may positively affect metabolic health. However, eating midpoint, ea…
View article: The Impact of Housing Support Expenditure on Urban Residents’ Consumption—Evidence from China
The Impact of Housing Support Expenditure on Urban Residents’ Consumption—Evidence from China Open
Consumption plays an important role in economic growth and sustainable economic development. The Chinese government emphasizes the theme of promoting high-quality development. This aim has led to the implementation of strategies to expand …
View article: Real Type Experiment of 77 Series Transmission Tower in Jiangsu Based on Different Reinforcement Schemes
Real Type Experiment of 77 Series Transmission Tower in Jiangsu Based on Different Reinforcement Schemes Open
The old 77 series transmission tower is widely used. In recent years, many structural damage accidents have occurred due to its inability to adapt to the changing climate in some regions. Therefore, this paper has carried out structural re…
View article: Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study
Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study Open
Background: Fibrinogen albumin ratio (FAR) is significantly correlated with the severity and prognosis of cardiovascular disease (CVD). Arterial stiffness is an early lesion of CVD, but no studies have examined the correlation between arte…
View article: Corrigendum: The association between normal serum sodium levels and bone turnover in patients with type 2 diabetes
Corrigendum: The association between normal serum sodium levels and bone turnover in patients with type 2 diabetes Open
[This corrects the article DOI: 10.3389/fendo.2022.927223.].
View article: The association between normal serum sodium levels and bone turnover in patients with type 2 diabetes
The association between normal serum sodium levels and bone turnover in patients with type 2 diabetes Open
Background Sodium is a critically important component of bones, and hyponatremia has firmly been established as a risk factor associated with the incidence of fragility fractures. However, researches have also revealed that lower serum sod…
View article: Binocular Vision-Based Recognition Method for Table Tennis Motion Trajectory
Binocular Vision-Based Recognition Method for Table Tennis Motion Trajectory Open
The latest development in computer technology in sports has increased the popularity of ping pong among people. It calls for designing an intelligent table tennis robot using computer technology to cooperate with table tennis enthusiasts a…
View article: Comparisons of the Relationships Between Multiple Lipid Indices and Diabetic Kidney Disease in Patients With Type 2 Diabetes: A Cross-Sectional Study
Comparisons of the Relationships Between Multiple Lipid Indices and Diabetic Kidney Disease in Patients With Type 2 Diabetes: A Cross-Sectional Study Open
Background Dyslipidemia is a well-recognized risk factor for diabetic kidney disease (DKD) in patients with type 2 diabetes (T2D). Growing evidences have shown that compared with the traditional lipid parameters, some lipid ratios may prov…
View article: The Positive Relationship Between the Low-Density Lipoprotein Cholesterol/Apoprotein B Ratio and Bone Turnover Markers in Patients With Type 2 Diabetes
The Positive Relationship Between the Low-Density Lipoprotein Cholesterol/Apoprotein B Ratio and Bone Turnover Markers in Patients With Type 2 Diabetes Open
Background Dyslipidemia may contribute to low bone turnover in patients with type 2 diabetes (T2D) through mediating oxidative stress and atherosclerosis. The low-density lipoprotein cholesterol/apoprotein B (LDL-C/Apo B) ratio is a surrog…
View article: [Retracted] TTC7B Is a Novel Prognostic‐Related Biomarker in Glioma Correlating with Immune Infiltrates and Response to Oxidative Stress by Temozolomide
[Retracted] TTC7B Is a Novel Prognostic‐Related Biomarker in Glioma Correlating with Immune Infiltrates and Response to Oxidative Stress by Temozolomide Open
Background . Gliomas are one of the most prevalent malignant brain tumors. Hence, identifying biological markers for glioma is imperative. TTC7B (Tetratricopeptide Repeat Domain 7B) is a gene whose role in cancer in currently identified. T…
View article: The association between serum adenosine deaminase levels and Graves’ disease
The association between serum adenosine deaminase levels and Graves’ disease Open
Background Adenosine deaminase (ADA) is essential for the differentiation and maturation of lymphocytes, while lymphocytes infiltration in thyroid tissue is a vital pathological feature of Graves’ disease (GD). The aim of the present study…
View article: Serum adenosine deaminase levels are associated with diabetic kidney disease in type 2 diabetic patients
Serum adenosine deaminase levels are associated with diabetic kidney disease in type 2 diabetic patients Open
The aim of the present study was to evaluate the association between adenosine deaminase (ADA) levels and diabetic kidney disease (DKD) in patients with type 2 diabetes (T2D). In this study, patients with T2D who had been screened for DKD …
View article: The relationship between adenosine deaminase and heart rate-corrected QT interval in type 2 diabetic patients
The relationship between adenosine deaminase and heart rate-corrected QT interval in type 2 diabetic patients Open
Background Prolonged heart rate-corrected QT (QTc) interval may reflect poor prognosis of patients with type 2 diabetes (T2D). Serum adenosine deaminase (ADA) levels are related to hyperglycemia, insulin resistance (IR) and inflammation, w…
View article: P085 Expression profiling of Wnt pathway genes in colon biopsies of patients with Ulcerative Colitis
P085 Expression profiling of Wnt pathway genes in colon biopsies of patients with Ulcerative Colitis Open
Background There is an increasing demand of agents that can promote mucosal healing in Inflammatory Bowel Disease (IBD). Wnt/β-catenin signaling plays a critical role in epithelial regeneration and repair, and stimulating regeneration in t…
View article: Association of Stromal Cell-derived Factor-1 With Diabetic Kidney Disease in Type 2 Diabetic Patients
Association of Stromal Cell-derived Factor-1 With Diabetic Kidney Disease in Type 2 Diabetic Patients Open
Background: The present study was designed to explore whether serum stromal cell-derived factor-1 (SDF-1) levels were associated with albuminuria, estimated glomerular filtration rate (eGFR) and diabetic kidney disease (DKD), and detect wh…
View article: Serum stromal cell-derived factor-1 levels are associated with diabetic kidney disease in type 2 diabetic patients
Serum stromal cell-derived factor-1 levels are associated with diabetic kidney disease in type 2 diabetic patients Open
The present study was designed to explore whether serum stromal cell-derived factor-1 (SDF-1) levels were associated with diabetic kidney disease (DKD). Serum SDF-1 levels were measured by sandwich ELISA. Patients with an estimated glomeru…
View article: High Glucagon-to-C-peptide Ratio and Inadequate Glucose Control in Type 2 Diabetic Patients
High Glucagon-to-C-peptide Ratio and Inadequate Glucose Control in Type 2 Diabetic Patients Open
Objective : Unbalanced glucagon and insulin secretion may contribute to glucose fluctuations and inadequate glucose control in type 2 diabetic patients. This study aimed to investigate the relationship between the glucagon-to-C-peptide rat…
View article: Optimization of Sample Points for Monitoring Arable Land Quality by Simulated Annealing while Considering Spatial Variations
Optimization of Sample Points for Monitoring Arable Land Quality by Simulated Annealing while Considering Spatial Variations Open
With China’s rapid economic development, the reduction in arable land has emerged as one of the most prominent problems in the nation. The long-term dynamic monitoring of arable land quality is important for protecting arable land resource…
View article: Guidelines for reducing image retakes of general digital radiography
Guidelines for reducing image retakes of general digital radiography Open
Image retake of radiological examinations not only increases the risk of radiation exposure of the patients, but also wastes the medical resource and degrades the quality of services of the hospitals. This study aimed at discovering factor…
View article: Influence of Acarbose on Plasma Glucose Fluctuations in Insulin-Treated Patients with Type 2 Diabetes: A Pilot Study
Influence of Acarbose on Plasma Glucose Fluctuations in Insulin-Treated Patients with Type 2 Diabetes: A Pilot Study Open
Background and Aims. To evaluate the effect of adding acarbose on glycemic excursions measured by continuous glucose monitoring system (CGMS) in patients with type 2 diabetes mellitus (T2DM) already on insulin therapy. Materials and Method…