Yeun‐Chung Chang
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View article: Concurrent detection of papillary thyroid carcinoma and parathyroid adenoma in a hyperparathyroidism patient: Evidence from 18F-flourodeoxyglucose positron emission tomography/computed tomography
Concurrent detection of papillary thyroid carcinoma and parathyroid adenoma in a hyperparathyroidism patient: Evidence from 18F-flourodeoxyglucose positron emission tomography/computed tomography Open
View article: Validation of the APACHE‐II scoring system in critically ill patients diagnosed with COVID‐19 and admitted at a regional‐level hospital intensive care unit: A retrospective study
Validation of the APACHE‐II scoring system in critically ill patients diagnosed with COVID‐19 and admitted at a regional‐level hospital intensive care unit: A retrospective study Open
Background. The use of the Acute Physiology and Chronic Health Evaluation II (APACHE-II) scoring system to predict mortality in the intensive care unit (ICU) has not been validated for use in the coronavirus-19 (COVID-19) pandemic in the S…
View article: External Testing of a Deep Learning Model for Lung Cancer Risk from Low-Dose Chest CT
External Testing of a Deep Learning Model for Lung Cancer Risk from Low-Dose Chest CT Open
Sybil, an open-source deep learning model, predicted future lung cancer risk in Asian individuals with heavy smoking histories of at least 20 pack-years using low-dose CT scans, supporting its role in risk-based screening strategies, but d…
View article: Lymphopenia, IL6, and CCL2 after thoracic radiotherapy predict poor prognosis in patients with lung cancer
Lymphopenia, IL6, and CCL2 after thoracic radiotherapy predict poor prognosis in patients with lung cancer Open
Post-treatment lymphopenia and elevated serum IL-6 and CCL2 are significant prognostic markers in patients with NSCLC undergoing thoracic radiotherapy. Immunologic evaluation may guide adjuvant treatment strategies in NSCLC treated with ra…
View article: Reply to comment on “Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis”
Reply to comment on “Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis” Open
View article: Understanding East-West differences in subsolid nodules: prevalence and overdiagnosis implications in lung cancer screening
Understanding East-West differences in subsolid nodules: prevalence and overdiagnosis implications in lung cancer screening Open
Apart from differences in clinical management and health literacy regarding SSNs between Eastern and Western countries, the high prevalence of SSNs in Asian nations, particularly among females, significantly contributes to the issue of ove…
View article: Pharmacokinetics and Safety Profile of <scp>SNS812</scp>, a First in Human Fully Modified <scp>siRNA</scp> Targeting Wide‐Spectrum <scp>SARS</scp>‐<scp>CoV</scp>‐2, in Healthy Subjects
Pharmacokinetics and Safety Profile of <span>SNS812</span>, a First in Human Fully Modified <span>siRNA</span> Targeting Wide‐Spectrum <span>SARS</span>‐<span>CoV</span>‐2, in Healthy Subjects Open
Severe acute respiratory syndrome caused by the coronavirus (SARS‐CoV‐2) in the COVID‐19 pandemic has highlighted the need for effective treatments, as rapid viral mutations complicate therapeutic development. SNS812, a fully modified inha…
View article: Efficient Deep Learning Models Revolutionize Doctor’s Training for Point-of-Care Ultrasound
Efficient Deep Learning Models Revolutionize Doctor’s Training for Point-of-Care Ultrasound Open
Point-of-care ultrasound (PoCUS) is a valuable diagnostic tool for pericardial effusion (PCE). However, the time constraints for trainees and experts pose significant barriers to PoCUS learning. This study aims to develop a deep learning (…
View article: Long-term results of stereotactic arrhythmia radioablation for refractory ventricular Arrhythmias—A Taiwanese population study
Long-term results of stereotactic arrhythmia radioablation for refractory ventricular Arrhythmias—A Taiwanese population study Open
In patients with medication and catheter ablation refractory VT, STAR is associated with a marked acute reduction in the burden of VT. The acute response of VT burden reduction helps to bridge patients to the next treatment step of heart f…
View article: Advanced metabolomics-based approach to reveal new insights into Bisphenol A metabolism and its presence in human excreta and water bodies in Taiwan
Advanced metabolomics-based approach to reveal new insights into Bisphenol A metabolism and its presence in human excreta and water bodies in Taiwan Open
Bisphenol A (BPA) is an environmental contaminant and can be detected in foodstuffs. Hence, investigating BPA metabolism in humans is crucial because certain BPA metabolites may exhibit similar or even greater be toxicity than does the par…
View article: Repeated CT scans on 12,984 Asians to diagnose lung cancer once it is suspected
Repeated CT scans on 12,984 Asians to diagnose lung cancer once it is suspected Open
In Taiwan, lung cancer remains the leading cause of cancer-related fatalities, resulting in substantial healthcare expenses. This research aims to evaluate both the frequency and the costs of low-dose computed tomography (LDCT) in individu…
View article: Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan
Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan Open
BACKGROUND: Since 2010, Taiwan has conducted a population-based breast cancer screening programme that includes mobile units to improve the screening rate. This study aimed to compare the results of mobile breast cancer screening units wit…
View article: MS-20 enhances the gut microbiota-associated antitumor effects of anti-PD1 antibody
MS-20 enhances the gut microbiota-associated antitumor effects of anti-PD1 antibody Open
Cancer immunotherapy has been regarded as a promising strategy for cancer therapy by blocking immune checkpoints and evoking immunity to fight cancer, but its efficacy seems to be heterogeneous among patients. Manipulating the gut microbio…
View article: Quantification of Resection Margin following Sublobar Resection in Lung Cancer Patients through Pre- and Post-Operative CT Image Comparison: Utilizing a CT-Based 3D Reconstruction Algorithm
Quantification of Resection Margin following Sublobar Resection in Lung Cancer Patients through Pre- and Post-Operative CT Image Comparison: Utilizing a CT-Based 3D Reconstruction Algorithm Open
Sublobar resection has emerged as a standard treatment option for early-stage peripheral non-small cell lung cancer. Achieving an adequate resection margin is crucial to prevent local tumor recurrence. However, gross measurement of the res…
View article: 2024 multidisciplinary consensus on image‐guided lung tumor ablation from the Taiwan Academy of Tumor Ablation
2024 multidisciplinary consensus on image‐guided lung tumor ablation from the Taiwan Academy of Tumor Ablation Open
In this article, the multidisciplinary team of the Taiwan Academy of Tumor Ablation, who have expertise in treating lung cancer, present their perspectives on percutaneous image‐guided thermal ablation (IGTA) of lung tumors. The modified D…
View article: Clinical Variables and Radiomics Features for Predicting Pneumothorax in Patients Undergoing CT-guided Transthoracic Core Needle Biopsy
Clinical Variables and Radiomics Features for Predicting Pneumothorax in Patients Undergoing CT-guided Transthoracic Core Needle Biopsy Open
Purpose To develop a prediction model combining both clinical and CT texture analysis radiomics features for predicting pneumothorax complications in patients undergoing CT-guided core needle biopsy. Materials and Methods A total of 424 pa…
View article: CT findings as predictive factors for treatment failure in Mycobacterium abscessus complex lung disease: a retrospective cohort study
CT findings as predictive factors for treatment failure in Mycobacterium abscessus complex lung disease: a retrospective cohort study Open
View article: Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis
Hemorrhage risk prediction after computed tomography-guided lung biopsy: Clinical parameters and quantitative pulmonary vascular analysis Open
Higher-grade pulmonary hemorrhage may occur after CT-guided lung biopsy. Lesion depth, vessel density, and BV5 are independent risk factors for higher-grade pulmonary hemorrhage. Nomograms integrating clinical parameters and radiographic p…
View article: Texture-Embedded Generative Adversarial Nets for the Synthesis of 3d Pulmonary Nodules Computed Tomography Images
Texture-Embedded Generative Adversarial Nets for the Synthesis of 3d Pulmonary Nodules Computed Tomography Images Open
View article: P1.20-01 Computed Tomography-based Deep Learning Model for Spread Through Air Spaces Prediction in Ground-Glass Predominant Lung Adenocarcinoma
P1.20-01 Computed Tomography-based Deep Learning Model for Spread Through Air Spaces Prediction in Ground-Glass Predominant Lung Adenocarcinoma Open
View article: Polyarteritis nodosa with bead-like coronary aneurysm in identical twins
Polyarteritis nodosa with bead-like coronary aneurysm in identical twins Open
Learning points for cliniciansPolyarteritis nodosa as a systemic necrotizing vasculitis is mainly ranged from small-to medium-sized arteries and can develop to characteristic aneurysmal dilatation, thrombosis and segmental stenosis which l…
View article: Automated marker-free longitudinal infrared breast image registration by GA-PSO
Automated marker-free longitudinal infrared breast image registration by GA-PSO Open
The automated marker-free longitudinal Infrared (IR) breast image registration overcomes several challenges like no anatomic fiducial markers on the body surface, blurry boundaries, heat pattern variation by environmental and physiological…
View article: CT findings of 144 in-hospital patients with influenza pneumonia: A retrospective analysis
CT findings of 144 in-hospital patients with influenza pneumonia: A retrospective analysis Open
Thin-section chest CT scores correlated with clinical and laboratory parameters in in-hospital patients with influenza pneumonia.
View article: Clinical outcomes and risk factors of progressive pulmonary fibrosis in primary Sjögren’s syndrome-associated interstitial lung disease
Clinical outcomes and risk factors of progressive pulmonary fibrosis in primary Sjögren’s syndrome-associated interstitial lung disease Open
Background To investigate the clinical outcomes and risk factors associated with progressive fibrosing interstitial lung disease (PF-ILD) in patients with primary Sjögren’s syndrome-associated interstitial lung disease (pSjS-ILD). Methods …
View article: Lung Cancer Screening in Asia: An Expert Consensus Report
Lung Cancer Screening in Asia: An Expert Consensus Report Open
Asian countries face several challenges in implementing low-dose computed tomography screening, such as economic limitations, lack of efforts for early detection, and lack of specific government programs. Various strategies are suggested t…
View article: (535) A Novel Approach for Penile Venous Stripping Surgery and Bilateral Varicocelectomy on an Ambulatory Basis
(535) A Novel Approach for Penile Venous Stripping Surgery and Bilateral Varicocelectomy on an Ambulatory Basis Open
Introduction There are varied approaches for conducting varicocelectomy and penile venous surgery, which are not unified or conspicuously, being not above controversy in the later type either in methodology or routes for accessibility thus…
View article: (533) Penile Venous Stripping for Treating Patients with Erectile Dysfunction Secondary to a Minimally Invasive Prostatectomy
(533) Penile Venous Stripping for Treating Patients with Erectile Dysfunction Secondary to a Minimally Invasive Prostatectomy Open
Introduction A minimally invasive prostatectomy becomes a treatment of choice in patients with operable prostate cancer. However, it is not uncommon to encounter patients with erectile dysfunction (ED) secondary to this procedure. Objectiv…
View article: Data from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer
Data from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer Open
Purpose: Clinical features of epidermal growth factor receptor (EGFR) mutations, L858R, deletions in exon 19, T790M, and insertions in exon 20, in non–small cell lung cancer (NSCLC) are well known. The clinical significance of other…
View article: Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer
Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer Open
Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer
View article: Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer
Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer Open
Supplementary Tables 1-4 from Effectiveness of Tyrosine Kinase Inhibitors on “Uncommon” Epidermal Growth Factor Receptor Mutations of Unknown Clinical Significance in Non–Small Cell Lung Cancer