Chunguang Zhao
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View article: N20-P25 Amplitude can Predict Awakening from Coma
N20-P25 Amplitude can Predict Awakening from Coma Open
Background The objective of this study was to evaluate the relationship between the N20-P25 amplitude of short-latency somatosensory evoked potentials (SSEPs) and neurologic outcomes in patients in a coma state. Methods We retrospectively …
View article: N20 amplitude can predict awakening from coma
N20 amplitude can predict awakening from coma Open
Introduction: To evaluate the relationship between the N20 amplitude of short-latency somatosensory evoked potentials (SSEPs) and neurologic outcomes in patients in a coma state. Methods We retrospectively enrolled neurocritical patients w…
View article: Application of high-quality targeted temperature management guided by multimodal brain monitoring in brain protection of patients with cardiac arrest: A case series
Application of high-quality targeted temperature management guided by multimodal brain monitoring in brain protection of patients with cardiac arrest: A case series Open
Rationale: Cardiac arrest (CA) is an acute emergency with high mortality and is closely associated with the risk of brain damage or systemic ischemia–reperfusion injury, post-traumatic stress symptoms. Patient concerns: Targeted temperatur…
View article: Biofilm-based biocatalysis for β-cyclodextrin production by the surface-display of β-cyclodextrin glycosyltransferase in Bacillus subtilis
Biofilm-based biocatalysis for β-cyclodextrin production by the surface-display of β-cyclodextrin glycosyltransferase in Bacillus subtilis Open
β-cyclodextrin (β-CD) is an important cyclic oligosaccharide, which is widely applicated in foods, environmental protection, and cosmetics, primarily prepared from enzymatic synthesis in traditional industry. However, several challenges pe…
View article: Engineering Corynebacterium Glutamicum for Improved Biofilm Formation and L-Lysine Production in Continuous Fermentation
Engineering Corynebacterium Glutamicum for Improved Biofilm Formation and L-Lysine Production in Continuous Fermentation Open
View article: Correction to: Strategy for the design of a bioreactor for L-lysine immobilized fermentation using Corynebacterium glutamicun
Correction to: Strategy for the design of a bioreactor for L-lysine immobilized fermentation using Corynebacterium glutamicun Open
View article: Expression and characterization of α-L-arabinofuranosidase derived from Aspergillus awamori and its enzymatic degradation of corn byproducts with xylanase
Expression and characterization of α-L-arabinofuranosidase derived from Aspergillus awamori and its enzymatic degradation of corn byproducts with xylanase Open
In this study, α-L-arabinofuranosidase (AF) from Aspergillus awamori was heterologously expressed in Pichia pastoris X33, with a 1-fold increase in AF activity after codon and vector optimization. AF remained stable at 60-65 °C and display…
View article: Long non-coding RNA BBOX1-antisense RNA 1 enhances cell proliferation and migration and suppresses apoptosis in oral squamous cell carcinoma via the miR-3940-3p/laminin subunit gamma 2 axis
Long non-coding RNA BBOX1-antisense RNA 1 enhances cell proliferation and migration and suppresses apoptosis in oral squamous cell carcinoma via the miR-3940-3p/laminin subunit gamma 2 axis Open
Long non-coding RNAs (lncRNAs) play an essential role in oral squamous cell carcinoma (OSCC). We aimed to demonstrate the effects of lncRNA gamma-butyrobetaine hydroxylase 1 (BBOX1)-antisense RNA 1 (AS1) in OSCC and its regulatory mechanis…
View article: Differences in clinical characteristics between younger and older patients with COVID-19 and their relationship with the length of hospital stay
Differences in clinical characteristics between younger and older patients with COVID-19 and their relationship with the length of hospital stay Open
View article: MicroRNA 617 Targeting SERPINE1 Inhibited the Progression of Oral Squamous Cell Carcinoma
MicroRNA 617 Targeting SERPINE1 Inhibited the Progression of Oral Squamous Cell Carcinoma Open
Serpin family E member 1 (SERPINE1) is a serine proteinase inhibitor (serpin) upregulated in diverse types of cancer, including oral squamous cell carcinoma (OSCC), and it functions in an oncogenic role. Hence, exploring pathological mecha…
View article: [A school-aged boy with nephrotic syndrome with cough for one month and shortness of breath for half a month].
[A school-aged boy with nephrotic syndrome with cough for one month and shortness of breath for half a month]. Open
A boy, aged 6 years and 11 months, was admitted due to nephrotic syndrome for 2 years, cough for 1 month, and shortness of breath for 15 days. The boy had a history of treatment with hormone and immunosuppressant. Chest CT after the onset …
View article: Diagnostic and Predictive Levels of Calcium-binding Protein A8 and Tumor Necrosis Factor Receptor-associated Factor 6 in Sepsis-associated Encephalopathy
Diagnostic and Predictive Levels of Calcium-binding Protein A8 and Tumor Necrosis Factor Receptor-associated Factor 6 in Sepsis-associated Encephalopathy Open
Peripheral blood levels of S100A8 and TRAF6 in SAE patients were elevated and might be related to the severity of SAE and predict the outcome of SAE. The efficacy and specificity of S100A8 for SAE diagnosis were superior, despite its weak …
View article: Improvement of the production of L-tryptophan in Escherichia coli by application of a dissolved oxygen stage control strategy
Improvement of the production of L-tryptophan in Escherichia coli by application of a dissolved oxygen stage control strategy Open
Dissolved oxygen (DO) is a key parameter for the production of L-tryptophan, and maintenance of appropriate DO levels can be used to increase the formation of L-tryptophan and reduce the accumulation of acetate and glutamate. In addition, …
View article: Impact of deletion of the genes encoding acetate kinase on production of L-tryptophan by Escherichia coli
Impact of deletion of the genes encoding acetate kinase on production of L-tryptophan by Escherichia coli Open
The production of L-tryptophan was increased by reducing acetate accumulation through a decrease in acetate kinase activity by gene deletion. The effects of disruption of the genes for acetate kinase (ackA) and an enzyme with propionate/ac…