Chunling Jiang
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View article: Corrigendum to ‘Efficacy of prolonged intravenous lidocaine infusion for postoperative movement-evoked pain following hepatectomy’ (Br J Anaesth 2023; 131: 113–21)
Corrigendum to ‘Efficacy of prolonged intravenous lidocaine infusion for postoperative movement-evoked pain following hepatectomy’ (Br J Anaesth 2023; 131: 113–21) Open
View article: Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial
Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial Open
This trial was registered at ClinicalTrials.gov (NCT06006026) on 23 August 2023.
View article: Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial
Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial Open
Background The concurrent use of a ropivacaine transversus abdominis plane (TAP) block with intravenous lidocaine infusion, though effective for pain relief, raises safety concerns regarding local anesthetic systemic toxicity (LAST). This …
View article: [Effect of <i>Pp</i>2<i>cm</i> Gene Silencing on Mouse Macrophage Resistance Against <i>Staphylococcus aureus</i> Infection via TLR Pathway].
[Effect of <i>Pp</i>2<i>cm</i> Gene Silencing on Mouse Macrophage Resistance Against <i>Staphylococcus aureus</i> Infection via TLR Pathway]. Open
Silencing Pp2cm gene promotes the inflammatory response of macrophages to S. aureus infection. Moreover, the TLR pathway plays an important role in the inflammatory activation of macrophages.
View article: Supplementary Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
Supplementary Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6 Open
Supplementary Figures S1-S4.
View article: Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6 Open
Purpose: We previously reported that nelfinavir (NFV) induces G1 cell-cycle block and apoptosis selectively in liposarcoma cell lines due to increased SREBP-1 (sterol regulatory element binding protein-1) expression in th…
View article: Supplementary Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
Supplementary Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6 Open
Supplementary Figures S1-S4.
View article: Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6
Data from Nelfinavir Induces Liposarcoma Apoptosis through Inhibition of Regulated Intramembrane Proteolysis of SREBP-1 and ATF6 Open
Purpose: We previously reported that nelfinavir (NFV) induces G1 cell-cycle block and apoptosis selectively in liposarcoma cell lines due to increased SREBP-1 (sterol regulatory element binding protein-1) expression in th…
View article: TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury
TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury Open
Mechanical ventilation is a life-sustaining therapy for patients with respiratory failure but can cause further lung damage known as ventilator-induced lung injury (VILI). However, the intrinsic molecular mechanisms underlying recovery of …
View article: Response of resource allocation of <i>Saussurea leontodontoides</i> during its fruiting stage to the elevation
Response of resource allocation of <i>Saussurea leontodontoides</i> during its fruiting stage to the elevation Open
AimsOur objective is to study the differences between the reproduction characteristics and resource allocation of Saussurea leontodontoides in the fruiting stage across six levels of the elevation gradient, and analyze the relationship bet…
View article: Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study
Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study Open
View article: Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study
Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study Open
Background Delayed gastric emptying and the resultant “full stomach” is the most important risk factor for perioperative pulmonary aspiration. Using point-of-care gastric sonography, we aimed to investigate the prevalence of full stomach a…
View article: Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study
Point-of-care ultrasound defines gastric content in elective surgical patients with type 2 diabetes mellitus: a prospective cohort study Open
Background Delayed gastric emptying and the resultant “full stomach” is the most important risk factor for perioperative pulmonary aspiration. Using point-of-care gastric sonography, we aimed to investigate the prevalence of full stomach a…
View article: Point-of-care ultrasound defines gastric content in elective surgical patients with diabetes mellitus: a prospective cohort study
Point-of-care ultrasound defines gastric content in elective surgical patients with diabetes mellitus: a prospective cohort study Open
Background Delayed gastric emptying and the resultant “full stomach” is the most important risk factor for perioperative pulmonary aspiration. Using point-of-care gastric sonography, we aimed to investigate the prevalence of full stomach a…
View article: Preoperative education with image illustrations enhances the effect of tetracaine mucilage in alleviating postoperative catheter-related bladder discomfort: a prospective, randomized, controlled study
Preoperative education with image illustrations enhances the effect of tetracaine mucilage in alleviating postoperative catheter-related bladder discomfort: a prospective, randomized, controlled study Open
The trial was registered at www,clinicaltrials.gov with registration number NCT03199105 (retrospectively registered). Date of trial registration which is "June 26, 2017".
View article: The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury
The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury Open
Uncontrolled inflammatory response during sepsis predominantly contributes to the development of multiorgan failure and lethality. However, the cellular and molecular mechanisms for excessive production and release of proinflammatory cytok…
View article: Melatonin improves neurological outcomes and preserves hippocampal mitochondrial function in a rat model of cardiac arrest
Melatonin improves neurological outcomes and preserves hippocampal mitochondrial function in a rat model of cardiac arrest Open
Cerebral injury after cardiac arrest (CA)/cardiopulmonary resuscitation (CPR) has been implicated in the poor prognosis of CA survivors. This study was designed to evaluate the impact of melatonin on postresuscitation neurological outcomes…
View article: Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signaling
Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signaling Open
A patient's recovery from lung inflammatory injury or development of multi-system organ failure is determined by the host's ability to resolve inflammation and repair tissue damage, both of which require the clearance of apoptotic neutroph…
View article: Surgical resection of right ventricular rhabdomyoma under the guidance of transesophageal echocardiography on a beating heart
Surgical resection of right ventricular rhabdomyoma under the guidance of transesophageal echocardiography on a beating heart Open
Cardiac rhabdomyoma, a type of benign myocardial tumor, is regarded as the most common fetal cardiac tumor. Rhabdomyomas are usually found before birth or during the first year of life. It is widely accepted that rhabdomyomas are strongly …
View article: Inactivation of Rab11a GTPase in Macrophages Facilitates Phagocytosis of Apoptotic Neutrophils
Inactivation of Rab11a GTPase in Macrophages Facilitates Phagocytosis of Apoptotic Neutrophils Open
The timely and efficient clearance of apoptotic neutrophils by macrophages (efferocytosis) is required for the resolution of inflammation and tissue repair, but the regulatory mechanisms remain unclear. In this study, we investigated the r…
View article: Emulsified isoflurane treatment inhibits the cell cycle and respiration of human bronchial epithelial 16HBE cells in a p53-independent manner
Emulsified isoflurane treatment inhibits the cell cycle and respiration of human bronchial epithelial 16HBE cells in a p53-independent manner Open
Emulsified isoflurane (EIso), as a result of its rapid anesthetic induction, recovery and convenience, is widely used as a novel intravenous general anesthetic. Treatment with EIso can reduce injuries caused by ischemia/reperfusion (I/R) t…
View article: Modified Leukocyte Filter Removes Tumor Cells from the Salvaged Blood
Modified Leukocyte Filter Removes Tumor Cells from the Salvaged Blood Open
Since M-LDF can effectively remove and destroy cancer cells in the salvaged blood, it has great potential for clinical application.
View article: The interrelationship between cholinergic pathway in the magnocellular paraventricular nucleus and natriuresis
The interrelationship between cholinergic pathway in the magnocellular paraventricular nucleus and natriuresis Open
The central nervous system is known to play important roles in the regulation of renal sodium excretion. The present study was designed to reveal the interrelationship between cholinergic pathway in the magnocellular paraventricular nucleu…