Chunlong Zhang
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View article: SDMap: a comprehensive database of spatial drug perturbation maps
SDMap: a comprehensive database of spatial drug perturbation maps Open
The arrangement patterns and spatial distribution features of cells within tissues are key regulators of drug actions and cellular responses; however, the specific spatial microenvironment that mediates drug actions and efficacy remains to…
View article: Expanding the Role of PSMA-PET: A Novel Approach to Prostate Cancer Prognosis
Expanding the Role of PSMA-PET: A Novel Approach to Prostate Cancer Prognosis Open
View article: The relationship between frailty in older adults and anxiety and depression in china: propensity score matching and network analysis
The relationship between frailty in older adults and anxiety and depression in china: propensity score matching and network analysis Open
Objective Anxiety and depression are common mental disorders in the elderly. Concurrent frailty may lead to worse clinical outcomes. This study examined the network structures of anxiety and depression in frail and non-frail older adults. …
View article: Environmental and socio-economic sustainability assessment of remediation alternatives for a contaminated oil refinery site in Southern China
Environmental and socio-economic sustainability assessment of remediation alternatives for a contaminated oil refinery site in Southern China Open
Refineries are an important industrial legacy, emitting large amounts of petroleum hydrocarbons and highlighting the need for the green and sustainable remediation of contaminated oil refinery sites globally. This study aimed to evaluate t…
View article: Ancient notching or tokening as bookkeeping – Evidence from wood slips in China during 217–210 BCE
Ancient notching or tokening as bookkeeping – Evidence from wood slips in China during 217–210 BCE Open
View article: Mechanistic insights into phosphorus transformation mediated by Arthrobacter and Sordariomycetes under long-term high-volume swine manure application in a wheat-rice rotation system
Mechanistic insights into phosphorus transformation mediated by Arthrobacter and Sordariomycetes under long-term high-volume swine manure application in a wheat-rice rotation system Open
Introduction Understanding the impacts of sustained high-input swine manure on soil phosphorus (P), along with identifying and functionally characterizing P-associated microorganisms, can provide a scientific foundation for effective manag…
View article: Numerical simulation study of power output characteristics of vertical axis self-starting power generators
Numerical simulation study of power output characteristics of vertical axis self-starting power generators Open
View article: A Review of CiteSpace-Based Studies Regarding the Effects of Drought Stress on the Physiological Characteristics of Wheat (<i>Triticum aestivum</i> L.)
A Review of CiteSpace-Based Studies Regarding the Effects of Drought Stress on the Physiological Characteristics of Wheat (<i>Triticum aestivum</i> L.) Open
Drought is one of the most significant agrometeorological hazards which limit wheat production and yield. Wheat exhibits a variety of morphological, physiological, biochemical and molecular responses to drought stress. In this study, we si…
View article: Comment on “The effect of acupuncture on gastrointestinal recovery after abdominal surgery: a narrative review from clinical trials”
Comment on “The effect of acupuncture on gastrointestinal recovery after abdominal surgery: a narrative review from clinical trials” Open
View article: Correction: The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder
Correction: The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder Open
View article: Antibacterial activity of the biogenic volatile organic compounds from three species of bamboo
Antibacterial activity of the biogenic volatile organic compounds from three species of bamboo Open
Plant biogenic volatile organic compounds (BVOCs) possess ecological functions in antimicrobial benefits and air purification. The objectives of the study were to determine the differences in antimicrobial capacity of bamboo forests at dif…
View article: SPathDB: a comprehensive database of spatial pathway activity atlas
SPathDB: a comprehensive database of spatial pathway activity atlas Open
Spatial transcriptomics sequencing technology deepens our understanding of the diversity of cell behaviors, fates and states within complex tissue, which is often determined by the fine-tuning of regulatory network functional activities. T…
View article: The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder
The association between child maltreatment, cognitive reappraisal, negative coping styles, and non-suicidal self-injury in adolescents with major depressive disorder Open
This study is the first to use both structural equation modeling and network analysis to explore the explore the relationship between CM, CR, NC, and NSSI in adolescents with MDD, providing a theoretical basis for future early prevention a…
View article: Comprehensive analysis of consensus molecular subtypes for ovarian cancer from bulk to single-cell perspectives
Comprehensive analysis of consensus molecular subtypes for ovarian cancer from bulk to single-cell perspectives Open
View article: The landscape of programmed cell death-related lncRNAs in Alzheimer’s disease and Parkinson’s disease
The landscape of programmed cell death-related lncRNAs in Alzheimer’s disease and Parkinson’s disease Open
This study delivers a thorough analysis of long non-coding RNAs (lncRNAs) in regulating programmed cell death (PCD), vital for neurodegenerative diseases like Alzheimer's disease (AD) and Parkinson's disease (PD). We propose a new framewor…
View article: The biological roles of CD47 in ovarian cancer progression
The biological roles of CD47 in ovarian cancer progression Open
Ovarian cancer is one of the most lethal malignant tumors, characterized by high incidence and poor prognosis. Patients relapse occurred in 65–80% after initial treatment. To date, no effective treatment has been established for these pati…
View article: Evidence of Regulating Effect of Nitrogen Level on Ultramicrostructure and Mapping Elements of Tomato (<em>Lycopersiconesculentum</em> Mill.) Chloroplast under Heat Stress
Evidence of Regulating Effect of Nitrogen Level on Ultramicrostructure and Mapping Elements of Tomato (<em>Lycopersiconesculentum</em> Mill.) Chloroplast under Heat Stress Open
Heat stress is a serious threat to tomato production. The ultrastructure and element mapping of tomato chloroplast were investigated under different nitrogen levels to explore the regulatory effect of nitrogen on tomato chloroplast under h…
View article: The relationship between childhood maltreatment and non-suicidal self-injury in adolescents with depressive disorders
The relationship between childhood maltreatment and non-suicidal self-injury in adolescents with depressive disorders Open
This study aims to explore the core symptoms of Non-Suicidal Self-Injury (NSSI) in adolescents with depressive disorders and the relationship between childhood maltreatment (CM) and NSSI symptoms by using network analysis. A total of 689 a…
View article: Heat Stress Recovery of Chlorophyll Fluorescence in Tomato (Lycopersicon esculentum Mill.) Leaves through Nitrogen Levels
Heat Stress Recovery of Chlorophyll Fluorescence in Tomato (Lycopersicon esculentum Mill.) Leaves through Nitrogen Levels Open
To study the impact of nitrogen application on the photosynthetic structure and photosystem activity of tomato (Lycopersicon esculentum Mill.) leaves during the recovery stage after heat stress, the OJIP curve and JIP parameters were deter…
View article: Inheritance of Aromatic Traits in a Yunnan Aromatic Rice Landrace without fgr allele
Inheritance of Aromatic Traits in a Yunnan Aromatic Rice Landrace without fgr allele Open
The most important aroma component 2-acetyl-1-pyrroline(2-AP) in aromatic rice is accumulated due to the presence of the fgr gene on chromosome 8 in rice. In a previous study, during the detection of the fgr aroma gene in a large number of…
View article: Correction to: Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo
Correction to: Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo Open
View article: Effects of Nitrogen Application in Recovery Period after Different High Temperature Stress on Plant Growth of Greenhouse Tomato at Flowering and Fruiting Stages
Effects of Nitrogen Application in Recovery Period after Different High Temperature Stress on Plant Growth of Greenhouse Tomato at Flowering and Fruiting Stages Open
High temperatures have become a severe factor limiting growth and yield for tomatoes (Lycopersicon esculentum Mill.) due to unfavorable, above-optimum temperatures. Temperature and nitrogen application were the main regulatory factors in t…
View article: Prioritizing exhausted T cell marker genes highlights immune subtypes in pan-cancer
Prioritizing exhausted T cell marker genes highlights immune subtypes in pan-cancer Open
View article: DNA hypomethylation mediates immune response in pan-cancer
DNA hypomethylation mediates immune response in pan-cancer Open
Abnormal DNA methylation is a fundamental characterization of epigenetics in cancer. Here we demonstrate that aberrant DNA methylating can modulate the tumour immune microenvironment in 16 cancer types. Differential DNA methylation in prom…
View article: CiTSA: a comprehensive platform provides experimentally supported signatures of cancer immunotherapy and analysis tools based on bulk and scRNA-seq data
CiTSA: a comprehensive platform provides experimentally supported signatures of cancer immunotherapy and analysis tools based on bulk and scRNA-seq data Open
View article: Three versus four cycles of neoadjuvant chemotherapy for muscle-invasive bladder cancer: a systematic review and meta-analysis
Three versus four cycles of neoadjuvant chemotherapy for muscle-invasive bladder cancer: a systematic review and meta-analysis Open
The optimal cycle of neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) remains controversial. This study aimed to compare the efficacy of three and four cycles of NAC in the treatment of MIBC through a systematic rev…
View article: DNA hypomethylation mediates immune response in pan-cancer
DNA hypomethylation mediates immune response in pan-cancer Open
Abnormal DNA methylation is a fundamental characterization of epigenetics in cancer. Here we demonstrate that aberrant DNA methylating can modulate the tumour immune microenvironment in 16 cancer types. Differential DNA methylation in prom…
View article: Exogenous Carbon Addition Mediated Phosphorus Dynamics Under 8-Years Continuous Input of Swine Manure in Wheat-Rice Rotation
Exogenous Carbon Addition Mediated Phosphorus Dynamics Under 8-Years Continuous Input of Swine Manure in Wheat-Rice Rotation Open
View article: A novel method to identify and characterize personalized functional driver lncRNAs in cancer samples
A novel method to identify and characterize personalized functional driver lncRNAs in cancer samples Open
Cancer is a highly heterogeneous disease, and different individuals of the same cancer type can display different therapeutic effects and prognosis. Genetic variation of long non-coding RNA is the key factor driving tumor development, and …
View article: Fluxes, patterns and sources of phosphorus deposition in an urban–rural transition region in Southwest China
Fluxes, patterns and sources of phosphorus deposition in an urban–rural transition region in Southwest China Open
Understanding the patterns of atmospheric phosphorus (P) deposition is essential for assessing the global P biogeochemical cycle. Atmospheric P is an essential source of P in agricultural activities as well as eutrophication in waters; how…