Chunping Shen
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View article: Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China
Multi-Omics Profiling of the 42-Day Infant Gut as a Pilot Predictor of Atopic Dermatitis at One Year: A Birth Cohort Study in China Open
Multi-omics profiling of the infant gut at 42 days identified microbial and metabolic features associated with later AD development. These findings support the gut-skin axis and suggest potential early-life biomarkers for predicting AD ris…
View article: Research waste among randomized controlled trials in preterm infants: a Cross-sectional study
Research waste among randomized controlled trials in preterm infants: a Cross-sectional study Open
Nearly 70% of RCTs involving preterm infants exhibited features of research waste. However, large-scale RCTs conducted in North America and Europe were less likely to contribute to this issue.
View article: A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areas
A Prospective Observational Study to Evaluate the Actual Use of 1% Pimecrolimus in Chinese Patients with Mild-to-Moderate Atopic Dermatitis Affecting Sensitive Skin Areas Open
This study provides robust real-world evidence that PIM 1% cream is effective for the treatment of mild-to-moderate AD in Chinese patients, particularly in sensitive skin areas and paediatric population. PIM also offers a TCS-sparing appro…
View article: Development and validation of the atopic dermatitis and infant skincare knowledge, attitude, and practice (ADISKAP 1.0) scale
Development and validation of the atopic dermatitis and infant skincare knowledge, attitude, and practice (ADISKAP 1.0) scale Open
Importance Preserving skin health is crucial for atopic dermatitis control as well as for the thriving of children. However, a well‐developed and validated tool that measures the knowledge, attitude, and practice of skin care is lacking. O…
View article: Preventive Antenatal Educational Program on Allergic Diseases (PAEPAD) versus standard antenatal care for prevention of atopic dermatitis: study protocol for a single-centre, investigator-blinded randomised controlled trial
Preventive Antenatal Educational Program on Allergic Diseases (PAEPAD) versus standard antenatal care for prevention of atopic dermatitis: study protocol for a single-centre, investigator-blinded randomised controlled trial Open
Introduction Patient education serves an essential purpose in the long-term management of allergic diseases as a secondary prevention approach. However, evidence on using education for primary prevention is limited. This study aims to eval…
View article: Either transepidermal water loss rates or stratum corneum hydration levels can predict quality of life in children with atopic dermatitis
Either transepidermal water loss rates or stratum corneum hydration levels can predict quality of life in children with atopic dermatitis Open
Importance Patients with atopic dermatitis (AD) display compromised epidermal barrier and suffer from poor quality of life. We hypothesized that quality of life could reflect in the changes in the epidermal barrier function. Objective To d…
View article: Distinct Skin Microbiota Imbalance and Responses to Clinical Treatment in Children With Atopic Dermatitis
Distinct Skin Microbiota Imbalance and Responses to Clinical Treatment in Children With Atopic Dermatitis Open
Background: Atopic dermatitis (AD) is a common cutaneous disease, associated with imbalances in the skin microbiota. Objective: To explore the characteristics of the cutaneous microbiota and its dynamic changes during clinica…
View article: Patient Education Programs in Pediatric Atopic Dermatitis: A Systematic Review of Randomized Controlled Trials and Meta-Analysis
Patient Education Programs in Pediatric Atopic Dermatitis: A Systematic Review of Randomized Controlled Trials and Meta-Analysis Open
Structured patient education is beneficial and should be implemented for the management of AD patients. However, an optimal delivery mode needs to be determined.
View article: <p>A Randomized Pilot Clinical Assessment Of Three Skincare Regimens On Skin Conditions In Infants</p>
A Randomized Pilot Clinical Assessment Of Three Skincare Regimens On Skin Conditions In Infants Open
A regimen of a liquid baby wash and a baby skin lotion for 12 weeks resulted in less detrimental changes in instrumental and clinical measures of skin than using water and lotion or water alone.
View article: A topical heparinoid‐containing product improves epidermal permeability barrier homeostasis in mice
A topical heparinoid‐containing product improves epidermal permeability barrier homeostasis in mice Open
Because of the importance of epidermal functions, including stratum corneum hydration and maintenance of permeability barrier homeostasis, in the pathogenesis of a variety of cutaneous and systemic disorders, a wide range of products has b…
View article: Prevalence of Atopic Dermatitis in Chinese Children aged 1–7 ys
Prevalence of Atopic Dermatitis in Chinese Children aged 1–7 ys Open
View article: Impaired Function of CD5+CD19+CD1dhi B10 Cells on IgE Secretion in an Atopic Dermatitis-Like Mouse Model
Impaired Function of CD5+CD19+CD1dhi B10 Cells on IgE Secretion in an Atopic Dermatitis-Like Mouse Model Open
Atopic dermatitis (AD) is a chronic inflammatory pruritic skin disease in which the pathogenic mechanism is complicated and not completely understood. Reports on the role of regulated cells in AD have recently evolved to regulate B cells, …