Chun‐Quan Ou
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View article: Effectiveness of the National Immunisation Programme and the catch-up vaccination on the incidence of hepatitis B in China: an interrupted time series analysis from 2005 to 2019
Effectiveness of the National Immunisation Programme and the catch-up vaccination on the incidence of hepatitis B in China: an interrupted time series analysis from 2005 to 2019 Open
Introduction In 2002, hepatitis B vaccines were incorporated into China’s National Immunisation Programme (NIP). In 2009, the catch-up vaccination was introduced for children born between 1994 and 2001. Sustained impacts of the NIP, partic…
View article: Rutin Suppresses EMT and Induces Mitochondrial Biogenesis <i>via</i> ER Stress-linked AMPK/SIRT1 Signaling in Prostate Cancer Cells
Rutin Suppresses EMT and Induces Mitochondrial Biogenesis <i>via</i> ER Stress-linked AMPK/SIRT1 Signaling in Prostate Cancer Cells Open
Rutin inhibits prostate cancer progression by suppressing EMT, inducing mitochondrial biogenesis, and acting via ER stress-linked AMPK/SIRT1 signaling. These findings suggest that Rutin may serve as a potential therapeutic candidate for ad…
View article: Trends and cross-country inequities by region, sex, age in the mortality, incidence, and disability-adjusted life years of COVID-19: Analysis from the Global Burden of Disease Study 2021
Trends and cross-country inequities by region, sex, age in the mortality, incidence, and disability-adjusted life years of COVID-19: Analysis from the Global Burden of Disease Study 2021 Open
Background The coronavirus disease 2019 (COVID-19) pandemic has imposed a substantial disease burden globally and has further exacerbated pre-existing health inequities. This study aimed to provide a comprehensive assessment of the burden …
View article: Relative associations of coffee, tea and plain water with all-cause and cause-specific mortality: a prospective cohort study
Relative associations of coffee, tea and plain water with all-cause and cause-specific mortality: a prospective cohort study Open
Previous studies highlighted the health benefits of coffee and tea, but they only focused on the comparisons between different consumptions. Consequently, the association estimate lacked a clear interpretation, as the substitution of bever…
View article: Open-Vocabulary Object Detection in UAV Imagery: A Review and Future Perspectives
Open-Vocabulary Object Detection in UAV Imagery: A Review and Future Perspectives Open
Due to its extensive applications, aerial image object detection has long been a hot topic in computer vision. In recent years, advancements in unmanned aerial vehicle (UAV) technology have further propelled this field to new heights, givi…
View article: Open-Vocabulary Object Detection in UAV Imagery: A Review and Future Perspectives
Open-Vocabulary Object Detection in UAV Imagery: A Review and Future Perspectives Open
Due to its extensive applications, aerial image object detection has long been a hot topic in computer vision. In recent years, advancements in Unmanned Aerial Vehicles (UAV) technology have further propelled this field to new heights, giv…
View article: Thermal Environment Analysis of Kunming's Micro-Scale Area Based on Mobile Observation Data
Thermal Environment Analysis of Kunming's Micro-Scale Area Based on Mobile Observation Data Open
This study compares mobile observation data from the same study area in Kunming on January 15, 2020, and January 8, 2023, to investigate the changes in micro-scale urban thermal environment characteristics under different weather condition…
View article: Spatiotemporal characteristics and influential factors of coupling coordination degree of urbanization and ecological environment in the Huaihe River ecological economic belt
Spatiotemporal characteristics and influential factors of coupling coordination degree of urbanization and ecological environment in the Huaihe River ecological economic belt Open
The rapid development of urbanization in recent years has led to significant economic and social progress, but it has also resulted in a series of eco-environmental challenges. This study, based on an evaluation model of urbanization and e…
View article: Comparison of different approaches in handling missing data in longitudinal multiple-item patient-reported outcomes: a simulation study
Comparison of different approaches in handling missing data in longitudinal multiple-item patient-reported outcomes: a simulation study Open
PPMs imputation at the item level was preferable for MNAR, whereas MMRM and MICE imputation at the item level were better for other scenarios. These findings provide valuable insight for selecting appropriate methods for handling missing P…
View article: Association between various blood glucose variability-related indicators during early ICU admission and 28-day mortality in non-diabetic patients with sepsis
Association between various blood glucose variability-related indicators during early ICU admission and 28-day mortality in non-diabetic patients with sepsis Open
High levels of GluCV, GluSD, M-value, J-index, HBGI, and LBGI on the first day of ICU admission were important risk markers of hospital mortality among non-diabetic patients with sepsis.
View article: Functional Characterization of the PoWHY1 Gene from Platycladus orientalis and Its Role in Abiotic Stress Tolerance in Transgenic Arabidopsis thaliana
Functional Characterization of the PoWHY1 Gene from Platycladus orientalis and Its Role in Abiotic Stress Tolerance in Transgenic Arabidopsis thaliana Open
The frequent occurrence of extreme weather conditions in the world has brought many unfavorable factors to plant growth, causing the growth and development of plants to be hindered and even leading to plant death, with abiotic stress hinde…
View article: New Ideas in Narrative Practice for Mind and Body Healing
New Ideas in Narrative Practice for Mind and Body Healing Open
To enrich the specific methods of narrative clinical practice in Chinese medicine and stimulate the innovation of narrative medicine practice in China, we advise that medical professionals should integrate theories and treatments related t…
View article: Early prediction of sepsis in emergency department patients using various methods and scoring systems
Early prediction of sepsis in emergency department patients using various methods and scoring systems Open
Background Early recognition of sepsis, a common life‐threatening condition in intensive care units (ICUs), is beneficial for improving patient outcomes. However, most sepsis prediction models were trained and assessed in the ICU, which mi…
View article: The Mediating Roles of Lung Function Traits and Inflammatory Factors on the Associations between Measures of Obesity and Risk of Lower Respiratory Tract Infections: A Mendelian Randomization Study
The Mediating Roles of Lung Function Traits and Inflammatory Factors on the Associations between Measures of Obesity and Risk of Lower Respiratory Tract Infections: A Mendelian Randomization Study Open
Background: Identifying mediators between obesity-related traits and lower respiratory tract infections (LRTIs) would inform preventive and therapeutic strategies to reduce the burden of LRITs. We aimed to recognize whether lung function a…
View article: Mortality risk and burden of aortic aneurysm and dissection attributable to low temperatures: A nationwide case-crossover analysis in Brazil, a predominantly tropical country
Mortality risk and burden of aortic aneurysm and dissection attributable to low temperatures: A nationwide case-crossover analysis in Brazil, a predominantly tropical country Open
This study highlights that low temperatures were associated with an increased risk of aortic-related deaths, with a remarkable burden even in this predominantly tropical country.
View article: The Association of Malnutrition and Health-Related Factors among 474,467 Older Community-Dwellers: A Population-Based Data Mining Study in Guangzhou, China
The Association of Malnutrition and Health-Related Factors among 474,467 Older Community-Dwellers: A Population-Based Data Mining Study in Guangzhou, China Open
Background: This study aimed to examine the prevalence and associated factors of malnutrition in older community-dwellers and explore the interaction between associated factors. Methods: A total of 474,467 older community-dwellers aged 65 …
View article: Rising trend and regional disparities of the global burden of disease attributable to ambient low temperature, 1990-2019: An analysis of data from the Global Burden of Disease 2019 study
Rising trend and regional disparities of the global burden of disease attributable to ambient low temperature, 1990-2019: An analysis of data from the Global Burden of Disease 2019 study Open
Our findings emphasise the significance of raising public awareness and prioritising policies to protect global population health from the adverse effects of low temperatures, even in the face of global warming. Particular efforts should b…
View article: The Effectiveness of National Expanded Program on Immunization With Hepatitis A Vaccines in the Chinese Mainland: Interrupted Time-Series Analysis
The Effectiveness of National Expanded Program on Immunization With Hepatitis A Vaccines in the Chinese Mainland: Interrupted Time-Series Analysis Open
Background The high prevalence of hepatitis A delivered a blow to public health decades ago. The World Health Organization (WHO) set a goal to eliminate viral hepatitis including hepatitis A by 2030. In 2008, hepatitis A vaccines were inte…
View article: Differences in the attitudes towards resuscitation of extremely premature infants between neonatologists and obstetricians: a survey study in China
Differences in the attitudes towards resuscitation of extremely premature infants between neonatologists and obstetricians: a survey study in China Open
Objectives Neonatologists and obstetricians are crucial decision-makers regarding the resuscitation of extremely preterm infants (EPIs). However, there is a scarcity of research regarding the differing perspectives on EPI resuscitation bet…
View article: Association between daily 1‐km resolution levels of ambient air pollution and hospital visits for allergic diseases
Association between daily 1‐km resolution levels of ambient air pollution and hospital visits for allergic diseases Open
Allergic diseases are extremely common disorders. Air pollutants may play an important role in inducing and exacerbating symptoms, resulting in significant increases in hospital visits.1, 2 Previous studies commonly evaluated the effects o…
View article: A Novel Clinical Tool to Detect Severe Obstructive Sleep Apnea
A Novel Clinical Tool to Detect Severe Obstructive Sleep Apnea Open
Based on common clinical examination of admission, we develop a novel model and a nomogram for identifying severe OSA from inpatient with suspected OSA, which provides physicians with a visual and easy-to-use tool for screening severe OSA.