Chunrong Gu
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View article: Risk analysis of noise-induced hearing loss of workers in the automobile manufacturing industries based on back-propagation neural network model: a cross-sectional study in Han Chinese population
Risk analysis of noise-induced hearing loss of workers in the automobile manufacturing industries based on back-propagation neural network model: a cross-sectional study in Han Chinese population Open
Objectives This study aims to predict the risk of noise-induced hearing loss (NIHL) through a back-propagation neural network (BPNN) model. It provides an early, simple and accurate prediction method for NIHL. Design Population based, a cr…
View article: Performance optimization and parameters estimation for MIMO-OFDM dual-functional communication-radar systems
Performance optimization and parameters estimation for MIMO-OFDM dual-functional communication-radar systems Open
Dual-function communication radar systems use common Radio Frequency (RF) signals are used for both communication and detection. For better compatibility with existing communication systems, we adopt Multiple-Input Multiple-Output (MIMO) O…
View article: SP70 is a novel biomarker of hepatocellular carcinoma
SP70 is a novel biomarker of hepatocellular carcinoma Open
Background Tumor-specific protein 70 (SP70) was identified as a new biomarker associated with the proliferation and invasion of cancer cells. This study aimed to investigate the expression of SP70 in hepatocellular carcinoma (HCC) and asse…
View article: Performance Optimization and Parameters Estimation for MIMO-OFDM Dual-functional Communication-radar Systems
Performance Optimization and Parameters Estimation for MIMO-OFDM Dual-functional Communication-radar Systems Open
In dual-functional communication-radar systems, common radio frequency (RF) signals are used for both communication and detection. For better compatibility with existing communication systems, we adopt multiple-input multiple-output (MIMO)…
View article: Role of CASP7 polymorphisms in noise-induced hearing loss risk in Han Chinese population
Role of CASP7 polymorphisms in noise-induced hearing loss risk in Han Chinese population Open
View article: <scp>MAb NJ001</scp> inhibits lung adenocarcinoma invasiveness by directly regulating <scp>TIMP</scp>‐3 promoter activity via <scp>FOXP1</scp> binding sites
<span>MAb NJ001</span> inhibits lung adenocarcinoma invasiveness by directly regulating <span>TIMP</span>‐3 promoter activity via <span>FOXP1</span> binding sites Open
Background Previously, we developed a monoclonal antibody (mAb) NJ001 that binds to the antigen SP70 in human non‐small cell lung cancer (NSCLC) cells and showed it could inhibit lung adenocarcinoma (AD) growth. Here, we investigated the e…
View article: Role of CASP7 polymorphisms in noise-induced hearing loss risk in Han Chinese population
Role of CASP7 polymorphisms in noise-induced hearing loss risk in Han Chinese population Open
Background: Genetic factors and gene-environment interaction may play an important role in the development of noise induced hearing loss (NIHL). This study explored the relationship between the SNP of CASP genes and the NIHL susceptibility…
View article: SP70-Targeted Imaging for the Early Detection of Lung Adenocarcinoma
SP70-Targeted Imaging for the Early Detection of Lung Adenocarcinoma Open
NJ001 is a monoclonal antibody that can specifically recognize the SP70 antigen on lung adenocarcinoma cells. The goal of this study was to explore its utility in targeted imaging. Subcutaneous xenograft and orthotopic lung tumor implantat…
View article: Serum <scp>SP</scp>70 is a sensitive predictor of chemotherapy response in patients with advanced nonsmall cell lung cancer
Serum <span>SP</span>70 is a sensitive predictor of chemotherapy response in patients with advanced nonsmall cell lung cancer Open
SP 70 is a novel tumor biomarker in patients with nonsmall cell lung cancer ( NSCLC ). However, its role as a marker for predicting the response to chemotherapy for patients with advanced NSCLC has not been investigated. A total of 152 pat…
View article: Astragaloside IV Prevents Cardiac Remodeling in the Apolipoprotein E-Deficient Mice by Regulating Cardiac Homeostasis and Oxidative Stress
Astragaloside IV Prevents Cardiac Remodeling in the Apolipoprotein E-Deficient Mice by Regulating Cardiac Homeostasis and Oxidative Stress Open
Background: Hypercholesterolemia is a risk factor for the development of cardiac hypertrophy. Astragaloside IV (AST-IV) possesses cardiovascular protective properties. We hypothesize that AST-IV prevents cardiac remodeling with hypercholes…
View article: In Vitro Effects of Hollow Gold Nanoshells on Human Aortic Endothelial Cells
In Vitro Effects of Hollow Gold Nanoshells on Human Aortic Endothelial Cells Open
Gold nanoparticles are emerging as promising biomedical tools due to their unique nanoscale characteristics. Our purpose was to synthesize a hollow-shaped gold nanoparticle and to investigate its effect on human aortic endothelial cells (H…
View article: The effects of different initiation time of exercise training on left ventricular remodeling and cardiopulmonary rehabilitation in patients with left ventricular dysfunction after myocardial infarction
The effects of different initiation time of exercise training on left ventricular remodeling and cardiopulmonary rehabilitation in patients with left ventricular dysfunction after myocardial infarction Open
Purpose: The purpose of this study was to determine whether different initiation of exercise training (ET) produces different effect sizes for left ventricular (LV) remodeling and cardiopulmonary rehabilitation in patients with LV d…
View article: Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells
Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells Open
Angiotensin II (Ang II)-induced mitochondrial dysfunction is a prominent characteristic of the majority of cardiovascular diseases. Astragaloside IV (As-IV), the major active ingredient of Astragalus membranaceus (Fisch.) Bge. (a tradition…