Chunying Liu
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View article: Transcriptome profiling and field evaluation reveal salt tolerance mechanisms in a novel wheat mutant
Transcriptome profiling and field evaluation reveal salt tolerance mechanisms in a novel wheat mutant Open
To analyze salt-tolerant genes and related metabolic pathways in wheat and to screen for salt-tolerant germplasm resources, the common wheat variety ‘Ningchun No. 4’ and its mutant Mutant-6 were used as experimental materials. Seedlings we…
View article: Efficacy and safety of naphlimostat mesylate versus sodium citrate in CRRT for EICU patients with coagulation dysfunction: A STROBE-compliant observational study
Efficacy and safety of naphlimostat mesylate versus sodium citrate in CRRT for EICU patients with coagulation dysfunction: A STROBE-compliant observational study Open
This study aimed to evaluate the safety of naphlimostat mesylate (NM) as an anticoagulant in vitro for emergency intensive care unit patients with coagulation dysfunction undergoing continuous renal replacement therapy (CRRT). Patients req…
View article: Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming
Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming Open
BACKGROUND Small bowel adenocarcinoma (SBA) is a rare malignant tumor of gastrointestinal tract. Currently, there is no standard treatment approach for late-stage SBA, which lead to poor outcome and prognosis. Rapamycin is an immunosuppres…
View article: Molecularly imprinted framework materials: design, synthesis, applications, and perspectives
Molecularly imprinted framework materials: design, synthesis, applications, and perspectives Open
View article: Bibliometric analysis of immunogenic cell death in hepatocellular carcinoma
Bibliometric analysis of immunogenic cell death in hepatocellular carcinoma Open
View article: SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma
SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma Open
BACKGROUND Metabolic dysregulation is considered a significant hallmark of hepatocellular carcinoma (HCC). SAC3 domain containing 1 (SAC3D1) functions in the cell cycle, and its expression is upregulated in various cancers. It is known tha…
View article: Exploring the prognostic role and expression patterns of FAM3A family genes in kidney renal clear cell carcinoma
Exploring the prognostic role and expression patterns of FAM3A family genes in kidney renal clear cell carcinoma Open
Kidney renal clear cell carcinoma (KIRC) is the most common subtype of kidney cancer, characterized by complex molecular alterations. The FAM3 gene family, comprising FAM3A, FAM3B, FAM3C, and FAM3D, has been implicated in various cancers, …
View article: Mesenchymal stem cell-derived exosomes and the Wnt/β-catenin pathway: Unifying mechanisms of multi-organ regeneration and the path to precision clinical translation
Mesenchymal stem cell-derived exosomes and the Wnt/β-catenin pathway: Unifying mechanisms of multi-organ regeneration and the path to precision clinical translation Open
In this editorial, we discuss the article by Fu Y et al , indicating that hair development is influenced by exosomes from human adipose-derived stem/stromal cell-mediated cell-to-cell communication via the Wnt/β-catenin pathway. In recent …
View article: Yangxinshi tablet protects against myocardial injury and increases skeletal muscle exercise capacity by regulating mitochondrial bioenergetics
Yangxinshi tablet protects against myocardial injury and increases skeletal muscle exercise capacity by regulating mitochondrial bioenergetics Open
This study revealed that YXST improved cardiac function and exercise tolerance in I/R mice, particularly we found that YXST could directly enhance the exercise capacity of mice under normal condition. Mechanismly, YXST significantly regula…
View article: Muscle wasting and the response to exercise in lung-injured mice is not primarily driven through the glucocorticoid axis
Muscle wasting and the response to exercise in lung-injured mice is not primarily driven through the glucocorticoid axis Open
The endogenous glucocorticoid axis is known to influence skeletal muscle structure and function and is activated during stress. Its role in driving muscle wasting and the response to exercise in the context of lung injury is unknown. Here …
View article: Developing a predictive model for septic shock risk in acute pancreatitis patients using interpretable machine learning algorithms
Developing a predictive model for septic shock risk in acute pancreatitis patients using interpretable machine learning algorithms Open
Background Septic shock is a severe complication of acute pancreatitis (AP), often associated with poor prognosis. This study aims to analyze the clinical characteristics of patients with acute pancreatitis and develop an interpretable ear…
View article: Genome-wide identification of Zinc Finger-Homeodomain (ZF-HD) gene family and expression analysis during abiotic stress in rye
Genome-wide identification of Zinc Finger-Homeodomain (ZF-HD) gene family and expression analysis during abiotic stress in rye Open
Adverse environmental conditions, encompassing both biotic and abiotic stresses, are critical factors that significantly impact the normal growth and development of plants worldwide, leading to increasingly severe consequences in recent ye…
View article: Hypocalcemia was associated with increased perioperative blood loss and blood transfusion in elderly patients with hip fracture: a retrospective study
Hypocalcemia was associated with increased perioperative blood loss and blood transfusion in elderly patients with hip fracture: a retrospective study Open
Hypocalcemia was associated with increased TBL and blood transfusion in elderly patients with hip fracture during the perioperative period.
View article: Volatile profiling from thermal decomposition of Amadori compounds in the alanine-glucose Maillard reaction: An DFT insight of 3-ethyl-2,5-dimethylpyrazine forming mechanism
Volatile profiling from thermal decomposition of Amadori compounds in the alanine-glucose Maillard reaction: An DFT insight of 3-ethyl-2,5-dimethylpyrazine forming mechanism Open
View article: Integrated analysis of lipid metabolism and differentially expressed genes reveal seed oil accumulation in field muskmelon
Integrated analysis of lipid metabolism and differentially expressed genes reveal seed oil accumulation in field muskmelon Open
Field muskmelon (Cucumis melo L. var. agrestis Naud.), a novel oil crop, contains a high amount of lipids in seeds. However, the high-resolution profiles and dynamic regulation of its lipids remain largely unknown. This study identified th…
View article: CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling
CD146 regulates the stemness and chemoresistance of hepatocellular carcinoma via JAG2-NOTCH signaling Open
CD146 plays a key role in cancer progression and metastasis. Cancer stem cells (CSCs) are responsible for tumor initiation, drug resistance, metastasis, and recurrence. In this study, we explored the role of CD146 in the regulation of live…
View article: Enhancing cooking and eating quality of semi-dried brown rice noodles through Lactobacillus fermentation and moderate lysine addition
Enhancing cooking and eating quality of semi-dried brown rice noodles through Lactobacillus fermentation and moderate lysine addition Open
Various concentrations of lysine were added to Lactobacillus fermentum-fermented brown rice flour to examine their effects on the sensory evaluation, color, pH, cooking quality, and texture of the resulting noodles. The potential me…
View article: Artificial intelligence-driven strategies for managing renal and urinary complications in inflammatory bowel disease
Artificial intelligence-driven strategies for managing renal and urinary complications in inflammatory bowel disease Open
In this editorial, we discuss the article by Singh et al published in World Journal of Nephrology , stating the need for timely adjustments in inflammatory bowel disease (IBD) patients' long-term management plans. IBD is chronic and lifelo…
View article: Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report
Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report Open
Rationale: Thrombotic microangiopathies (TMA) caused by malignant hypertension is an acute and critical disease among rare diseases. Although renal biopsy pathology is a golden indicator for diagnosing kidney disease, it cannot distinguish…
View article: Novel molecular design breeding strategies enabled by genome resequencing in melon
Novel molecular design breeding strategies enabled by genome resequencing in melon Open
View article: Methods for the Construction and Editing of an Efficient Control Network for the Photogrammetric Processing of Massive Planetary Remote Sensing Images
Methods for the Construction and Editing of an Efficient Control Network for the Photogrammetric Processing of Massive Planetary Remote Sensing Images Open
Planetary photogrammetry remains an important technical means of producing high-precision planetary maps. High-quality control networks are fundamental to successful bundle adjustment. However, current software tools used by the planetary …
View article: Early use of low-dose hydrocortisone can reduce in-hospital mortality in patients with septic shock: A systematic review and meta-analysis
Early use of low-dose hydrocortisone can reduce in-hospital mortality in patients with septic shock: A systematic review and meta-analysis Open
Background: This study aimed to assess the impact of the timing of low-dose hydrocortisone adjuvant therapy initiation on clinical outcomes in patients with septic shock by a systematic review and meta-analysis. Methods: We conducted a com…
View article: Self-Compassion and Psychological Flourishing Among College Students: The Mediating Role of Hope and the Moderating Role of Emotion Regulation
Self-Compassion and Psychological Flourishing Among College Students: The Mediating Role of Hope and the Moderating Role of Emotion Regulation Open
College students face pressure from various aspects such as academics, employment, and interpersonal relationships, and their mental health is receiving increasing attention. This study used a cross-sectional, descriptive correlational des…
View article: CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity Open
View article: Shenqifuzheng injection inhibits lactic acid-induced cisplatin resistance in NSCLC by affecting FBXO22/p53 axis through FOXO3
Shenqifuzheng injection inhibits lactic acid-induced cisplatin resistance in NSCLC by affecting FBXO22/p53 axis through FOXO3 Open
SQFZ influences LA-induced DDP resistance in NSCLC via FOXO3/FBXO22/p53 pathway, providing a promising agent for NSCLC treatment.
View article: PKG1 promotes the HIV-induced proliferation, migration, and fibrosis of vascular smooth muscle cells of hemorrhoids
PKG1 promotes the HIV-induced proliferation, migration, and fibrosis of vascular smooth muscle cells of hemorrhoids Open
View article: Icariside II Preparation from Icariin Separated from <i>Epimedium</i> Herbal Extract Powder by a Special Icariin Glycosidase
Icariside II Preparation from Icariin Separated from <i>Epimedium</i> Herbal Extract Powder by a Special Icariin Glycosidase Open
In this study, icariside II was prepared from icariin by a special enzyme. The yield of the substrate icariin from a powdered extract of the popular herb Epimedium was 16.9%. The enzyme, which was produced from Aspergillus sp…
View article: Early use of low-dose hydrocortisone can reduce in-hospital mortality in patients with septic shock:A systematic review and meta-analysis
Early use of low-dose hydrocortisone can reduce in-hospital mortality in patients with septic shock:A systematic review and meta-analysis Open
View article: A study on Chinese Medicine to alleviate the Adverse Effects of Western Medicine in the Treatment of Lupus Nephritis
A study on Chinese Medicine to alleviate the Adverse Effects of Western Medicine in the Treatment of Lupus Nephritis Open
Lupus nephritis (LN) is the most serious and common complication of systemic lupus erythematosus (SLE), which is mainly treated with glucocorticoids combined with immunosuppressive drugs, but its long-term use in large quantities can produ…
View article: The Relationship between Maladaptive Perfectionism and Anxiety in First-Year Undergraduate Students: A Moderated Mediation Model
The Relationship between Maladaptive Perfectionism and Anxiety in First-Year Undergraduate Students: A Moderated Mediation Model Open
To clarify the underlying mechanism of first-year undergraduate students’ maladaptive perfectionism in relation to their anxiety, this study constructs a mediating model with moderation, focusing on the investigation of the mediating role …