Chuyu Shen
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View article: Prognostic Value of the C-reactive Protein-to-Lymphocyte Ratio (CLR) for Lupus Nephritis: Comparison With Neutrophil-to-Lymphocyte Ratio (NLR) and Fibrinogen-to-Albumin Ratio (FAR)
Prognostic Value of the C-reactive Protein-to-Lymphocyte Ratio (CLR) for Lupus Nephritis: Comparison With Neutrophil-to-Lymphocyte Ratio (NLR) and Fibrinogen-to-Albumin Ratio (FAR) Open
Background This study aimed to evaluate the prognostic value of C-reactive protein-to-lymphocyte ratio (CLR) in lupus nephritis (LN), and compare its utility with neutrophil-to-lymphocyte ratio (NLR) and fibrinogen-to-albumin ratio (FAR). …
View article: Bidirectional Sparse Attention for Faster Video Diffusion Training
Bidirectional Sparse Attention for Faster Video Diffusion Training Open
Video diffusion Transformer (DiT) models excel in generative quality but hit major computational bottlenecks when producing high-resolution, long-duration videos. The quadratic complexity of full attention leads to prohibitively high train…
View article: SMOC2 promotes aggressive behavior of fibroblast-like synoviocytes in rheumatoid arthritis through transcriptional and post-transcriptional regulating MYO1C
SMOC2 promotes aggressive behavior of fibroblast-like synoviocytes in rheumatoid arthritis through transcriptional and post-transcriptional regulating MYO1C Open
Fibroblast-like synoviocytes (FLSs), play a key role in perpetuating synovial inflammation and bone erosion in rheumatoid arthritis (RA), however, the underlying mechanism(s) of RA FLSs activation and aggression remain unclear. Identifying…
View article: Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2
Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2 Open
Objective: To explore the effect and underlying mechanism of Myricitrin (Myr) in regulating fibroblast-like synoviocyte (FLS)-mediated synovitis and joint destruction in RA. Methods: FLSs were isolated from synovial tissues from patients w…
View article: Risk Factors Associated With Lower Bone Mineral Density in Primary Aldosteronism Patients
Risk Factors Associated With Lower Bone Mineral Density in Primary Aldosteronism Patients Open
Purpose The association between primary aldosteronism (PA) and lower bone mineral density (BMD) has raised a concern, but the contributing factors remain unclear. We aim to explore the risk factors for lower BMD in PA patients. Methods We …
View article: cGAS/STING signaling in the regulation of rheumatoid synovial aggression
cGAS/STING signaling in the regulation of rheumatoid synovial aggression Open
Our findings suggest that cGAS/STING signaling has an important role in regulating rheumatoid synovial aggression and that targeting cGAS/STING may represent a novel potential therapy for RA.
View article: Machine Learning Algorithms Identify Clinical Subtypes and Cancer in Anti-TIF1γ+ Myositis: A Longitudinal Study of 87 Patients
Machine Learning Algorithms Identify Clinical Subtypes and Cancer in Anti-TIF1γ+ Myositis: A Longitudinal Study of 87 Patients Open
Background Anti-TIF1γ antibodies are a class of myositis-specific antibodies (MSAs) and are closely associated with adult cancer-associated myositis (CAM). The heterogeneity in anti-TIF1γ+ myositis is poorly explored, and whether anti-TIF1…
View article: Increased long noncoding RNA LINK-A contributes to rheumatoid synovial inflammation and aggression
Increased long noncoding RNA LINK-A contributes to rheumatoid synovial inflammation and aggression Open
Fibroblast-like synoviocytes (FLSs) play a key role in controlling synovial inflammation and joint destruction in rheumatoid arthritis (RA). The contribution of long noncoding RNAs (lncRNAs) to RA is largely unknown. Here, we show that the…
View article: LncRNA THRIL is involved in the proliferation, migration, and invasion of rheumatoid fibroblast-like synoviocytes
LncRNA THRIL is involved in the proliferation, migration, and invasion of rheumatoid fibroblast-like synoviocytes Open
Reduced expression of lncRNA THRIL represses the proliferation, migration, and invasion of RA FLSs, suggesting that lncRNA THRIL might be a potential target for RA therapy.
View article: Infective patterns of cryptococcosis in patients with connective tissue disease: a retrospective study
Infective patterns of cryptococcosis in patients with connective tissue disease: a retrospective study Open
Background: Cryptococcal infection is a life-threatening complication in patients with connective tissue disease (CTD). This retrospective study was performed to explore the clinical features and associated factors of cryptococcosis in pat…
View article: Infective patterns of cryptococcosis in patients with connective tissue disease:a retrospective study
Infective patterns of cryptococcosis in patients with connective tissue disease:a retrospective study Open
Background: Cryptococcal infection is a life-threatening complication in patients with connective tissue disease (CTD). This retrospective study was performed to explore the clinical features and associated factors of cryptococcosis in pat…