Cian Ward
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View article: High-fidelity and differential nonsense suppression in live cells and a frontotemporal dementia allele with human transfer RNAs
High-fidelity and differential nonsense suppression in live cells and a frontotemporal dementia allele with human transfer RNAs Open
Nonsense mutations generate premature termination codons (PTCs) that are responsible for 11% of genetic disease alleles. The arginine (Arg, CGA) to stop (UGA) mutation is the most common PTC. Humans encode >600 transfer RNA (tRNA) genes…
View article: Effect of Egg Washing and Hen Age on Cuticle Quality and Bacterial Adherence in Table Eggs
Effect of Egg Washing and Hen Age on Cuticle Quality and Bacterial Adherence in Table Eggs Open
The cuticle covering the outer surface of an eggshell functions as both a physical and chemical barrier against invading microorganisms. Contamination of eggs by microbial pathogens progresses in four stages: bacterial attachment to the eg…
View article: Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury Open
Concussion is a mild traumatic brain injury (mTBI) defined as complex neurological impairment induced by biomechanical forces without structural brain damage. There does not yet exist an objective diagnostic tool for concussion. Downstream…
View article: Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer
Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer Open
Real-time quaking-induced conversion (RT-QuIC) assays have become a common tool to detect chronic wasting disease (CWD) and are very sensitive provided the assay duration is sufficient. However, a prolonged assay duration may lead to non-s…
View article: Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer
Optimization of RT-QuIC Assay Duration for Screening Chronic Wasting Disease in White-Tailed Deer Open
Real-time quaking-induced conversion (RT-QuIC) assays have become common in the detection of chronic wasting disease (CWD) and are very sensitive provided the assay duration is sufficient. However, a prolonged assay duration may lead to no…