Ciara Kirke
YOU?
Author Swipe
View article: iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review
iSIMPATHY: a multinational pre–post non-randomised intervention study transforming medication review Open
Background Taking multiple medicines can be appropriate but has the potential to be problematic. The Implementing Stimulating Innovation in the Management of Polypharmacy and Adherence THrough the Years (iSIMPATHY) project used the 7-Steps…
View article: Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022
Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022 Open
Background The trends in sedative use have varied in recent years. Benzodiazepines and z-drugs are indicated for anxiety and/or sleep disorders but should be limited to short-term use. The aim of this study is to examine trends and pattern…
View article: Patterns of Analgesic Prescribing and High‐Risk Prescribing in Primary Care in Ireland 2014–2022—A Repeated Cross‐Sectional Study
Patterns of Analgesic Prescribing and High‐Risk Prescribing in Primary Care in Ireland 2014–2022—A Repeated Cross‐Sectional Study Open
Background Pain is a significant burden on individuals, healthcare systems and society. Analgesic drugs carry many therapeutic benefits; however, all drugs are associated with adverse effects and risk of harm. Non‐steroidal anti‐inflammato…
View article: Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study
Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study Open
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 201…
View article: Association between socioeconomic status and dispensing of higher-risk drug classes and polypharmacy in older community-based populations: a nationwide cohort study
Association between socioeconomic status and dispensing of higher-risk drug classes and polypharmacy in older community-based populations: a nationwide cohort study Open
Background Higher-risk medications are associated with increased risk of medication-related harm in older populations. Aim To investigate the association between socioeconomic status (SES) and the prescribing of higher-risk drug classes an…
View article: Identifying predictors of medication-related harm in older populations: a latent class analysis approach
Identifying predictors of medication-related harm in older populations: a latent class analysis approach Open
Background The aim of this study was to apply latent class analysis to identify underlying groupings of predictors, including drug classes and clinical predictors, co-occurring in older people at higher risk of medication-related harm. Met…
View article: RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland Open
Background The Health Service Executive (HSE) in Ireland releases monthly reports on prescription dispensing claims and payments relating to community drug schemes. This paper describes the implementation of an R-based Shiny application th…
View article: Patterns of analgesic prescribing and high-risk prescribing in primary care in Ireland 2014-2022 – a repeated cross-sectional study
Patterns of analgesic prescribing and high-risk prescribing in primary care in Ireland 2014-2022 – a repeated cross-sectional study Open
Background Pain is a significant burden on individuals, healthcare systems, and society. Analgesic drugs carry many therapeutic benefits; however, all drugs are associated with adverse effects and risk of harm. Non-steroidal anti-inflammat…
View article: Person-Centered approach to improve wellbeing and outcomes from medicines: iSIMPATHY (Stimulating Innovation in management of Polypharmacy, Adherence Through the Years)
Person-Centered approach to improve wellbeing and outcomes from medicines: iSIMPATHY (Stimulating Innovation in management of Polypharmacy, Adherence Through the Years) Open
Introduction: Inappropriate polypharmacy and adherence impact adversely on both population health and quality of life and health system burden and costs. The EU-funded SIMPATHY project identified recommendations to manage polypharmacy in E…
View article: A Quantitative Study Exploring and Comparing Key Factors in Medication Management in the Irish Healthcare Setting
A Quantitative Study Exploring and Comparing Key Factors in Medication Management in the Irish Healthcare Setting Open
Background Shared decision‐making in the context of medication management has been shown to be contingent on information‐seeking behaviours such as patient knowledge, self‐efficacy and engagement. Objective The aim of this study was to: (i…
View article: RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland
RxTrends: An R-based Shiny Application for Visualising Open Data on Prescribed Medications in Ireland Open
Background The Health Service Executive (HSE) in Ireland releases monthly reports on prescription dispensing claims and payments relating to community drug schemes. This paper describes the implementation of an R-based Shiny application th…
View article: Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures
Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures Open
Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported out…
View article: Development and evaluation of a national administrative code-based system for estimation of hospital-acquired venous thromboembolism in Ireland
Development and evaluation of a national administrative code-based system for estimation of hospital-acquired venous thromboembolism in Ireland Open
Background Hospital-acquired venous thromboembolism (HA-VTE) is a significant patient safety concern contributing to preventable deaths. Internationally, estimating HA-VTE relies on administrative codes, in particular the International Cla…
View article: Adverse drug reactions and events in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development and validation of a model for predicting adverse drug reactions and events in older patients
Adverse drug reactions and events in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development and validation of a model for predicting adverse drug reactions and events in older patients Open
Purpose Older people are at an increased risk of developing adverse drug reactions (ADR) and adverse drug events (ADE). This study aimed to develop and validate a risk prediction model (ADAPTiP) for ADR/ADE in older populations. Methods We…
View article: Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study
Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study Open
Background The trends in sedative use have varied in recent years. Benzodiazepines and z-drugs are indicated for anxiety and sleep disorders, but should be limited to short term use. The aim of this study is to examine trends and patterns …
View article: Adverse Drug Reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: development of a prediction model related to hospital admissions
Adverse Drug Reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: development of a prediction model related to hospital admissions Open
Background Older patients are at an increased risk of developing adverse drug reactions (ADRs). The aim of this study was to develop a risk prediction model (ADAPTiP) for ADR-related hospital admissions in older populations, based on predi…
View article: Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022 - a repeated cross-sectional study
Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022 - a repeated cross-sectional study Open
Background Pain is a major public health issue, and a common reason people seek medical care. Pharmacological treatments depend on the type of pain and carry different risks and benefits. The aim of this study was to examine trends in anal…
View article: Adverse Drug reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development of a model for predicting adverse drug reaction-related hospital admissions in older patients
Adverse Drug reactions in an Ageing PopulaTion risk Prediction (ADAPTiP) tool: the development of a model for predicting adverse drug reaction-related hospital admissions in older patients Open
Background: Older patients are at an increased risk of developing adverse drug reactions (ADRs). The aim of this study was to develop a risk prediction model (ADAPTiP) for ADR-related hospital admissions in older populations, based on pred…
View article: Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions
Potentially Inappropriate Prescribing and Potential Prescribing Omissions and Their Association with Adverse Drug Reaction-Related Hospital Admissions Open
Background: This study aimed to determine the prevalence of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) and their association with ADR-related hospital admissions in patients aged ≥ 65 years admit…
View article: The impact of lidocaine plaster prescribing reduction strategies: a comparison of two national health services in Europe
The impact of lidocaine plaster prescribing reduction strategies: a comparison of two national health services in Europe Open
Introduction In 2017, two distinct interventions were implemented in Ireland and England to reduce prescribing of lidocaine medicated plasters. In Ireland, restrictions on reimbursement were introduced. In England, updated guidance on item…
View article: Adverse drug reactions in an ageing PopulaTion (ADAPT) study: Prevalence and risk factors associated with adverse drug reaction-related hospital admissions in older patients
Adverse drug reactions in an ageing PopulaTion (ADAPT) study: Prevalence and risk factors associated with adverse drug reaction-related hospital admissions in older patients Open
Background: Older people experience greater morbidity with a corresponding increase in medication use resulting in a potentially higher risk of adverse drug reactions (ADRs). Objectives: The aim of this study was to; 1) determine the preva…
View article: 145 ASSESSING MEDICINE LISTS: A QUALITATIVE STUDY WITH MULTIPLE STAKEHOLDERS
145 ASSESSING MEDICINE LISTS: A QUALITATIVE STUDY WITH MULTIPLE STAKEHOLDERS Open
Background Multimorbidity and polypharmacy often result in numerous interactions with different Healthcare Professionals (HCPs) and many transitions of care. Keeping up-to-date medications list in people taking medicines and/or carers can …
View article: Medication safety incidents associated with the remote delivery of primary care: a rapid review
Medication safety incidents associated with the remote delivery of primary care: a rapid review Open
Objectives The COVID-19 pandemic triggered rapid, fundamental changes, notably increased remote delivery of primary care. While the impact of these changes on medication safety is not yet fully understood, research conducted before the pan…
View article: ‘Everyone should know what they’re on’: a qualitative study of attitudes towards and use of patient held lists of medicines among patients, carers and healthcare professionals in primary and secondary care settings in Ireland
‘Everyone should know what they’re on’: a qualitative study of attitudes towards and use of patient held lists of medicines among patients, carers and healthcare professionals in primary and secondary care settings in Ireland Open
Objectives Managing multiple medicines can be challenging for patients with multimorbidity, who are at high risk of adverse outcomes, for example, hospitalisation. Patient-held medication lists (PHMLs) can contribute to patient safety and …
View article: Changes to primary care delivery during the COVID-19 pandemic and perceived impact on medication safety: A survey study
Changes to primary care delivery during the COVID-19 pandemic and perceived impact on medication safety: A survey study Open
During the pandemic, a number of significant changes occurred in primary care in Ireland, particularly involving communication of healthcare information, with varying impacts on workflow and medication safety. Future research should focus …
View article: Medication Safety Incidents Associated with the Remote Delivery of Primary Care: A Rapid Review
Medication Safety Incidents Associated with the Remote Delivery of Primary Care: A Rapid Review Open
Background The COVID-19 pandemic triggered rapid, fundamental changes in how healthcare is delivered in communities, notably increased remote delivery of primary care. While the impact of these changes on medication safety are not yet full…
View article: Evaluation of policies and practices to support safe and appropriate analgesic and sedative prescribing: The CDRx (controlled drug prescribing) protocol
Evaluation of policies and practices to support safe and appropriate analgesic and sedative prescribing: The CDRx (controlled drug prescribing) protocol Open
Medications provide many therapeutic benefits; however, these must be balanced against the potential for patient harm. Two high-risk medications are benzodiazepine receptor agonists or BZRAs (including benzodiazepines and Z-drugs hypnotics…