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View article: Forest fragment size shapes Trypanosoma cruzi transmission and vector-host dynamics in eastern Colombia
Forest fragment size shapes Trypanosoma cruzi transmission and vector-host dynamics in eastern Colombia Open
Chagas disease, caused by the protozoan Trypanosoma cruzi, remains a major public health challenge in Latin America. Its transmission dynamics are tightly governed by ecological factors that influence vector-host interactions. Habitat frag…
View article: Zoonotic Cycle of American Trypanosomiasis in an Endemic Region of the Argentine Chaco, Factors That Influenced a Paradigm Shift
Zoonotic Cycle of American Trypanosomiasis in an Endemic Region of the Argentine Chaco, Factors That Influenced a Paradigm Shift Open
Trypanosoma cruzi, the causative agent of Chagas disease (American trypanosomiasis), is a highly complex zoonosis that is present throughout South America, Central America, and Mexico. The transmission of this disease is influenced by vari…
View article: Pathogens, reservoirs, and vectors involved in the transmission of vector-borne and zoonotic diseases in a Colombian region
Pathogens, reservoirs, and vectors involved in the transmission of vector-borne and zoonotic diseases in a Colombian region Open
The ecology of vector-borne diseases (VBDs) is an important system of great complexity, which involves the knowledge about the pathogens and animal species entailed in maintaining transmission cycles in a given locality, including those th…
View article: Deadly and venomous Lonomia caterpillars are more than the two usual suspects
Deadly and venomous Lonomia caterpillars are more than the two usual suspects Open
Caterpillars of the Neotropical genus Lonomia (Lepidoptera: Saturniidae) are responsible for some fatal envenomation of humans in South America inducing hemostatic disturbances in patients upon skin contact with the caterpillars’ spines. C…
View article: Deadly and venomous <i>Lonomia</i> caterpillars are more than the two usual suspects
Deadly and venomous <i>Lonomia</i> caterpillars are more than the two usual suspects Open
Caterpillars of the Neotropical genus Lonomia (Lepidoptera: Saturniidae) are responsible for some fatal envenomation of humans in South America inducing hemostatic disturbances in patients upon skin contact with the caterpillars’ spines. C…
View article: Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application
Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application Open
Continued waves, new variants, and limited vaccine deployment mean that SARS-CoV-2 tests remain vital to constrain the coronavirus disease 2019 (COVID-19) pandemic. Affordable, point-of-care (PoC) tests allow rapid screening in non-medical…
View article: Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application
Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application Open
Continued waves, new variants, and limited vaccine deployment mean that SARS-CoV-2 tests remain vital to constrain the COVID-19 pandemic. Affordable, point-of-care (PoC) tests allow rapid screening in non-medical settings. Reverse-transcri…
View article: Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses
Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses Open
Background Dengue, Zika and chikungunya are arboviruses of significant public health importance that are transmitted by Aedes aegypti and Aedes albopictus mosquitoes. In Colombia, where dengue is hyperendemic, and where chikungunya and Zik…
View article: Additional file 2 of Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses
Additional file 2 of Entomological characterization of Aedes mosquitoes and arbovirus detection in Ibagué, a Colombian city with co-circulation of Zika, dengue and chikungunya viruses Open
Additional file 2: Table S2. Data on adult mosquitoes collected in Ibagué, Colombia. Table S3. Household questionnaire data, Ibagué, Colombia. Table S4. Mosquito molecular data, Ibagué, Colombia.
View article: Detection of Trypanosoma cruzi strains circulating in Córdoba department (Colombia) isolated from triatomines (Hemiptera: Reduviidae) collected by the community
Detection of Trypanosoma cruzi strains circulating in Córdoba department (Colombia) isolated from triatomines (Hemiptera: Reduviidae) collected by the community Open
Introduction: From 2011 to 2016, 24 cases of Chagas disease were reported in Córdoba according to the national public health surveillance system (Sistema Nacional de Vigilancia en Salud Pública, Sivigila), but the information regarding Try…
View article: Analytical Performance of a Loop-Mediated Isothermal Amplification Assay for Leishmania DNA Detection in Sandflies and Direct Smears of Patients with Cutaneous Leishmaniasis
Analytical Performance of a Loop-Mediated Isothermal Amplification Assay for Leishmania DNA Detection in Sandflies and Direct Smears of Patients with Cutaneous Leishmaniasis Open
Loop-mediated isothermal amplification (LAMP) is ideal for the detection of Leishmania DNA as it is a quick and easy-to-perform test that does not require complex or sophisticated equipment or infrastructure. However, the application of th…
View article: Diversity patterns, Leishmania DNA detection, and bloodmeal identification of Phlebotominae sand flies in villages in northern Colombia
Diversity patterns, Leishmania DNA detection, and bloodmeal identification of Phlebotominae sand flies in villages in northern Colombia Open
Leishmaniases are neglected tropical diseases exhibiting complex transmission cycles due to the number of parasite species circulating, sand fly species acting as vectors and infected mammals, including humans, which are defined in the New…
View article: Analytical Performance of Four Polymerase Chain Reaction (PCR) and Real Time PCR (qPCR) Assays for the Detection of Six Leishmania Species DNA in Colombia
Analytical Performance of Four Polymerase Chain Reaction (PCR) and Real Time PCR (qPCR) Assays for the Detection of Six Leishmania Species DNA in Colombia Open
Leishmaniasis comprises a spectrum of parasitic diseases caused by protozoans of the genus Leishmania. Molecular tools have been widely employed for the detection of Leishmania due to its high sensitivity and specificity. However, the anal…
View article: First Colombian consensus on congenital Chagas and clinical approach for women of child-bearing age diagnosed with Chagas
First Colombian consensus on congenital Chagas and clinical approach for women of child-bearing age diagnosed with Chagas Open
Congenital transmission of Chagas disease has not been extensively studied in Colombia, and there are no standardized processes in the health system regarding the specific diagnosis, treatment and follow-up of this disease. To generate rec…
View article: New Scenarios of Chagas Disease Transmission in Northern Colombia
New Scenarios of Chagas Disease Transmission in Northern Colombia Open
Chagas disease (CD) is a systemic parasitic infection caused by the flagellated form of Trypanosoma cruzi . Córdoba department, located in the Colombian Caribbean Coast, was not considered as a region at risk of T. cruzi transmission. In t…
View article: Murine models susceptibility to distinct<i>Trypanosoma cruzi</i>I genotypes infection
Murine models susceptibility to distinct<i>Trypanosoma cruzi</i>I genotypes infection Open
SUMMARY Chagas disease is a complex zoonosis that affects around 8 million people worldwide. This pathology is caused by Trypanosoma cruzi , a kinetoplastid parasite that shows tremendous genetic diversity evinced in six distinct Discrete …
View article: Correction: Molecular Diagnosis of Chagas Disease in Colombia: Parasitic Loads and Discrete Typing Units in Patients from Acute and Chronic Phases
Correction: Molecular Diagnosis of Chagas Disease in Colombia: Parasitic Loads and Discrete Typing Units in Patients from Acute and Chronic Phases Open
[This corrects the article DOI: 10.1371/journal.pntd.0004997.].
View article: Molecular Diagnosis of Chagas Disease in Colombia: Parasitic Loads and Discrete Typing Units in Patients from Acute and Chronic Phases
Molecular Diagnosis of Chagas Disease in Colombia: Parasitic Loads and Discrete Typing Units in Patients from Acute and Chronic Phases Open
The molecular tests are a precise tool to complement the standard diagnosis of Chagas disease, specifically in acute phase showing high discriminative power. However, it is necessary to improve the sensitivity of molecular tests in chronic…