Cindy Close
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View article: Bringing Attomolar Detection to the Point‐of‐Care with Nanopatterned DNA Origami Nanoantennas
Bringing Attomolar Detection to the Point‐of‐Care with Nanopatterned DNA Origami Nanoantennas Open
Creating increasingly sensitive and cost‐effective nucleic acid detection methods is critical for enhancing point‐of‐care (POC) applications. This requires highly specific capture of biomarkers and efficient transduction of capture events.…
View article: A Silicon Rhodamine‐fused Glibenclamide to Label and Detect Malaria‐infected Red Blood Cells
A Silicon Rhodamine‐fused Glibenclamide to Label and Detect Malaria‐infected Red Blood Cells Open
The malaria parasite Plasmodium falciparum affects the lives of millions of people worldwide every year. The detection of replicating parasites within human red blood cells is of paramount importance, requiring appropriate diagnostic tools…
View article: A silicon rhodamine-fused glibenclamide to label and detect malaria-infected red blood cells
A silicon rhodamine-fused glibenclamide to label and detect malaria-infected red blood cells Open
The malaria parasite Plasmodium falciparum affects the lives of millions of people worldwide every year. The detection of replicating parasites within human red blood cells is of paramount importance, requiring appropriate diagnostic tools…
View article: Minimally Invasive DNA-Mediated Photostabilization for Extended Single-Molecule and Super-resolution Imaging
Minimally Invasive DNA-Mediated Photostabilization for Extended Single-Molecule and Super-resolution Imaging Open
Photobleaching of fluorescence labels poses a major limitation in single-molecule and super-resolution microscopy. Conventional photostabilization methods, such as oxygen removal and addition of high concentrations of photostabilization ad…
View article: Bringing Attomolar Detection to the Point-of-Care with Nanopatterned DNA Origami Nanoantennas
Bringing Attomolar Detection to the Point-of-Care with Nanopatterned DNA Origami Nanoantennas Open
Creating increasingly sensitive and cost-effective nucleic acid detection methods is critical for enhancing point-of-care (POC) applications. This involves capturing all desired biomarkers in a sample with high specificity and transducing …
View article: Maximizing the Accessibility in DNA Origami Nanoantenna Plasmonic Hotspots (Adv. Mater. Interfaces 24/2022)
Maximizing the Accessibility in DNA Origami Nanoantenna Plasmonic Hotspots (Adv. Mater. Interfaces 24/2022) Open
Trident DNA Origami In article number 2200255, Cindy Close, Philip Tinnefeld, and co-workers demonstrate the development of a Trident DNA origami structure for single-molecule-based plasmonic biosensing. Trident NanoAntennas with Cleared H…
View article: Maximizing the Accessibility in DNA Origami Nanoantenna Plasmonic Hotspots
Maximizing the Accessibility in DNA Origami Nanoantenna Plasmonic Hotspots Open
DNA nanotechnology has conquered the challenge of positioning quantum emitters in the hotspot of optical antenna structures for fluorescence enhancement. Therefore, DNA origami serves as the scaffold to arrange nanoparticles and emitters, …
View article: Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope
Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope Open
View article: Addressable Nanoantennas with Cleared Hotspots for Single-Molecule Detection on a Portable Smartphone Microscope
Addressable Nanoantennas with Cleared Hotspots for Single-Molecule Detection on a Portable Smartphone Microscope Open
The advent of highly sensitive photodetectors 1,2 and the development of photostabilization strategies 3 made detecting the fluorescence of a single molecule a routine task in many labs around the world. However, to this day, this process …