Citsabehsan Devendran
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Making immotile sperm motile using high-frequency ultrasound Open
Sperm motility is a natural selection with a crucial role in both natural and assisted reproduction. Common methods for increasing sperm motility are by using chemicals that cause embryotoxicity, and the multistep washing requirements of t…
Fully Microfabricated Surface Acoustic Wave Tweezer for Collection of Submicron Particles and Human Blood Cells Open
Precise manipulation of (sub)micron particles is key for the preparation, enrichment, and quality control in many biomedical applications. Surface acoustic waves (SAW) hold tremendous promise for manipulation of (bio)particles at the micro…
Bacteriophages evolve enhanced persistence to a mucosal surface Open
The majority of viruses within the gut are obligate bacterial viruses known as bacteriophages (phages). Their bacteriotropism underscores the study of phage ecology in the gut, where they modulate and coevolve with gut bacterial communitie…
High‐Frequency Ultrasound Boosts Bull and Human Sperm Motility Open
Sperm motility is a significant predictor of male fertility potential and is directly linked to fertilization success in both natural and some forms of assisted reproduction. Sperm motility can be impaired by both genetic and environmental…
The role of channel height and actuation method on particle manipulation in surface acoustic wave (SAW)-driven microfluidic devices Open
Surface acoustic wave (SAW) micromanipulation offers modularity, easy integration into microfluidic devices and a high degree of flexibility. A major challenge for acoustic manipulation, however, is the existence of a lower limit on the mi…
Surface acoustic wave-driven pumpless flow for sperm rheotaxis analysis Open
We developed a device utilising acoustic streaming to drive a tuneable, well-regulated continuous flow in a microfluidic channel with suitable velocity range for probing sperm rheotaxis behaviour.
Bacteriophage adaptation to a mammalian mucosa reveals a trans-domain evolutionary axis Open
The majority of viruses within the human gut are obligate bacterial viruses known as bacteriophages (phages) 1 . Their bacteriotropism underscores the study of phage ecology in the gut, where they sustain top-down control 2–4 and co-evolve…
Tracheal branching in ants is area-decreasing, violating a central assumption of network transport models Open
The structure of tubular transport networks is thought to underlie much of biological regularity, from individuals to ecosystems. A core assumption of transport network models is either area-preserving or area-increasing branching, such th…
View article: Cell Adhesion, Morphology, and Metabolism Variation via Acoustic Exposure within Microfluidic Cell Handling Systems
Cell Adhesion, Morphology, and Metabolism Variation via Acoustic Exposure within Microfluidic Cell Handling Systems Open
Acoustic fields are capable of manipulating biological samples contained within the enclosed and highly controlled environment of a microfluidic chip in a versatile manner. The use of acoustic streaming to alter fluid flows and radiation f…
Versatile platform for performing protocols on a chip utilizing surface acoustic wave (SAW) driven mixing Open
We present a dextrous microfluidic device which features a reaction chamber with volume flexibility and acoustic mixing.
Self-Aligned Acoustofluidic Particle Focusing and Patterning in Microfluidic Channels from Channel-Based Acoustic Waveguides Open
Acoustic fields have been widely used for manipulation of particles and cells within microfluidic systems. In this Letter, we explore a novel acoustofluidic phenomenon for particle patterning and focusing, where a periodic acoustic pressur…
Surface acoustic wave diffraction driven mechanisms in microfluidic systems Open
We present five distinct mechanisms arising from the incidence of a finite-width surface acoustic waves (SAW) beam propagating into a quiescent fluid.
Huygens-Fresnel Acoustic Interference and the Development of Robust Time-Averaged Patterns from Traveling Surface Acoustic Waves Open
Periodic pattern generation using time-averaged acoustic forces conventionally requires the intersection of counterpropagating wave fields, where suspended micro-objects in a microfluidic system collect along force potential minimizing nod…
Acoustic tweezing of particles using decaying opposing travelling surface acoustic waves (DOTSAW) Open
Surface acoustic waves offer a versatile and biocompatible method of manipulating the location of suspended particles or cells within microfluidic systems.
Microfluidic batch process platforms for lab on a chip applications using acoustofluidics Open
The inception of microfluidics, utilising borrowed technology from the microelectronics industry, has enabled a wide range of applications in various fields ranging from engineering to biochemistry. Advancements in terms of microfabricatio…
Trapping and patterning of large particles and cells in a 1D ultrasonic standing wave Open
Acoustic forces can be used to pattern single particles; here, the required relationship between wavelength and particle radius is explored.
Acoustic tweezers via sub–time-of-flight regime surface acoustic waves Open
Researchers use pulsed excitation to generate localized 2D acoustic tweezers for spatially selective microfluidic patterning.
The importance of travelling wave components in standing surface acoustic wave (SSAW) systems Open
The dominant forcing mechanism for particle manipulation using SSAW is shown to be spatially dependent when travelling components are considered.
Flow-rate insensitive deterministic particle sorting using a combination of travelling and standing surface acoustic waves Open
Manipulation of cells by acoustic forces in a continuous flow offers a means to sort on the basis of physical properties in a contactless, label-free and biocompatible manner. Many acoustic sorting systems rely on either standing waves or …
Batch process particle separation using surface acoustic waves (SAW): integration of travelling and standing SAW Open
Acoustic fields are described incorporating travelling and standing wave components to perform size-deterministic particle sorting. This is achieved without the need for fluid flow allowing application to very small volumes in a batch-wise…
Virtual membrane for filtration of particles using surface acoustic waves (SAW) Open
Surface acoustic wave (SAW) based particle manipulation is contactless, versatile, non-invasive and biocompatible making it useful for biological studies and diagnostic technologies.