Colleen L. Lau
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View article: Targeted probe capture metagenomics-enabled surveillance of multidrug-resistant organisms and antimicrobial resistance genes in post-handwashing areas of public washrooms
Targeted probe capture metagenomics-enabled surveillance of multidrug-resistant organisms and antimicrobial resistance genes in post-handwashing areas of public washrooms Open
View article: Climate and community-level determinants of respiratory syncytial virus notifications among Queensland infants, prior to the introduction of the RSV Mother and Infant Protection Program (RSV-MIPP) immunisation initiative
Climate and community-level determinants of respiratory syncytial virus notifications among Queensland infants, prior to the introduction of the RSV Mother and Infant Protection Program (RSV-MIPP) immunisation initiative Open
Background Respiratory syncytial virus (RSV) is a highly infectious seasonal respiratory pathogen and a major cause of morbidity in young children. In Australia, RSV is the leading cause of hospitalisation for bronchiolitis and pneumonia a…
View article: Leptospirosis in the Caribbean Region between 2000 and 2022 – a Scoping Review of Morbidity and Mortality
Leptospirosis in the Caribbean Region between 2000 and 2022 – a Scoping Review of Morbidity and Mortality Open
Background Leptospirosis remains an important yet underreported public health concern in the Caribbean. Urbanisation, biodiversity loss and human encroachment into natural habitats have contributed to shifts in its epidemiological patterns…
View article: Deciphering Microscopic Agglutination Test (MAT) Serogroup Cross-Reactivity in Leptospirosis: The Influence of Age and Antibody Titers
Deciphering Microscopic Agglutination Test (MAT) Serogroup Cross-Reactivity in Leptospirosis: The Influence of Age and Antibody Titers Open
Leptospirosis is a zoonotic disease caused by Leptospira spp., with over 250 serovars classified into 24 serogroups. Control measures depend on understanding serovar-specific epidemiology, yet the microscopic agglutination test (MAT) is on…
View article: Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector‐Borne Neglected Tropical Diseases: A Systematic Review
Current Gaps in Survey Design and Analysis for Molecular Xenomonitoring of Vector‐Borne Neglected Tropical Diseases: A Systematic Review Open
Objectives Molecular xenomonitoring is a surveillance method for vector‐borne diseases where vectors are tested for molecular pathogen markers. Testing is typically on pools (groups) of vectors. Molecular xenomonitoring is a sensitive and …
View article: A Bayesian network analysis of the Pfizer COVID-19 vaccine in the paediatric population
A Bayesian network analysis of the Pfizer COVID-19 vaccine in the paediatric population Open
The Pfizer COVID-19 vaccines have been associated with an increased risk of myocarditis. However, COVID-19 infection is also associated with complications. A Bayesian network (BN), informed by Australian and international data, was created…
View article: Quantifying Spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model
Quantifying Spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model Open
View article: Reactive case detection can improve the efficiency of lymphatic filariasis surveillance compared to random sampling, Samoa 2023
Reactive case detection can improve the efficiency of lymphatic filariasis surveillance compared to random sampling, Samoa 2023 Open
Background In Samoa, lymphatic filariasis (LF) remains endemic despite persistent elimination efforts. Targeted sampling based on locations of known infections could be an efficient strategy for locating infected individuals and residual i…
View article: Urban gentrification and infectious diseases: an interdisciplinary narrative review
Urban gentrification and infectious diseases: an interdisciplinary narrative review Open
Urban gentrification, the transformation of neighbourhoods by influx of new residential groups, leading to displacement of lowerincome communities, is a complex, multifaceted process with significant but generally unexplored public health …
View article: Geospatial analysis of leptospirosis clusters and risk factors in two provinces of the Dominican Republic
Geospatial analysis of leptospirosis clusters and risk factors in two provinces of the Dominican Republic Open
Background Drivers of leptospirosis transmission can vary across regions, leading to spatial clustering of infections. This study aims to identify clusters of leptospirosis seroprevalence in the Dominican Republic (DR) and factors associat…
View article: The future of spatial epidemiology in the AI era: enhancing machine learning approaches with explicit spatial structure
The future of spatial epidemiology in the AI era: enhancing machine learning approaches with explicit spatial structure Open
Spatial epidemiology, defined as the study of spatial patterns in disease burdens or health outcomes, aims to estimate disease risk or incidence by identifying geographical risk factors and populations at risk (Morrison et al., 2024). Rese…
View article: Mapping the prevalence of soil-transmitted helminth infections in the Western Pacific Region: a spatial modelling study
Mapping the prevalence of soil-transmitted helminth infections in the Western Pacific Region: a spatial modelling study Open
National Health and Medical Research Council (1153727 ACE-NTD).
View article: Quantifying spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model
Quantifying spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model Open
Spatial variation in drivers of leptospirosis transmission in the Dominican Republic is poorly understood. To inform targeted public health interventions, we aimed to identify household-level variations in leptospirosis drivers. We analyse…
View article: Integrated serological surveillance for neglected tropical diseases, vaccine-preventable diseases, and arboviruses in Samoa, 2018
Integrated serological surveillance for neglected tropical diseases, vaccine-preventable diseases, and arboviruses in Samoa, 2018 Open
View article: Spatial multilevel analysis of individual, household, and community factors associated with COVID-19 vaccine hesitancy in the Dominican Republic
Spatial multilevel analysis of individual, household, and community factors associated with COVID-19 vaccine hesitancy in the Dominican Republic Open
View article: Persistent lymphatic filariasis transmission seven years after validation of elimination as a public health problem: a cross-sectional study in Tonga
Persistent lymphatic filariasis transmission seven years after validation of elimination as a public health problem: a cross-sectional study in Tonga Open
View article: Progression of lymphatic filariasis antigenaemia and microfilaraemia over 4.5 years in antigen-positive individuals, Samoa 2019-2023
Progression of lymphatic filariasis antigenaemia and microfilaraemia over 4.5 years in antigen-positive individuals, Samoa 2019-2023 Open
View article: Spatial prediction of immunity gaps during a pandemic to inform decision making: A geostatistical case study of <scp>COVID</scp>‐19 in Dominican Republic
Spatial prediction of immunity gaps during a pandemic to inform decision making: A geostatistical case study of <span>COVID</span>‐19 in Dominican Republic Open
Background To demonstrate the application and utility of geostatistical modelling to provide comprehensive high‐resolution understanding of the population's protective immunity during a pandemic and identify pockets with sub‐optimal protec…
View article: Effectiveness and impact of rotavirus vaccination, real-world study: a systematic review
Effectiveness and impact of rotavirus vaccination, real-world study: a systematic review Open
View article: The Utility of Infectious Disease Prevalence Studies to Inform Public Health Decision-Making in the Samoan Islands: A Systematic Review
The Utility of Infectious Disease Prevalence Studies to Inform Public Health Decision-Making in the Samoan Islands: A Systematic Review Open
We conducted a systematic review of infectious disease (ID) prevalence studies in the Samoan Islands from 2000 to 2024 and aimed to synthesise the prevalence of IDs, the purpose of the studies, and the potential utility of survey results f…
View article: Overseas- and locally acquired sexually transmissible infections in Australia, 2017–23
Overseas- and locally acquired sexually transmissible infections in Australia, 2017–23 Open
Introduction International travel is a significant contributor to the acquisition of sexually transmissible infections (STIs). Despite the high volume of outbound travel from Australia, peaking at 10.8 million travellers in 2023, limited d…
View article: Advancing adoptability and sustainability of digital prediction tools for climate-sensitive infectious disease prevention and control
Advancing adoptability and sustainability of digital prediction tools for climate-sensitive infectious disease prevention and control Open
Few forecasting models have been translated into digital prediction tools for prevention and control of climate-sensitive infectious diseases. We propose a 3-U (useful, usable, and used) research framework for advancing the adoptability an…
View article: A study protocol for developing a spatial vulnerability index for infectious diseases of poverty in the Caribbean region
A study protocol for developing a spatial vulnerability index for infectious diseases of poverty in the Caribbean region Open
Infectious diseases of poverty (IDoP) affect disproportionately resource-limited and marginalized populations, resulting in spatial patterns of vulnerability across various geographical areas. Currently, no spatial indices exist to quantif…
View article: Sensitivity of anti-filarial antibodies for lymphatic filariasis surveillance: Insights from a serological survey in Samoa in 2018
Sensitivity of anti-filarial antibodies for lymphatic filariasis surveillance: Insights from a serological survey in Samoa in 2018 Open
Background Sensitive diagnostic tools that signal lymphatic filariasis (LF) transmission are needed to monitor the progress of LF elimination programs. Anti-filarial antibody (Ab) markers could be more sensitive than antigen (Ag) point-of-…
View article: Recurrence of microfilaraemia after triple-drug therapy for lymphatic filariasis in Samoa: Recrudescence or reinfection?
Recurrence of microfilaraemia after triple-drug therapy for lymphatic filariasis in Samoa: Recrudescence or reinfection? Open
View article: Estimating risk of long COVID using a Bayesian network-based decision support tool
Estimating risk of long COVID using a Bayesian network-based decision support tool Open
Background: Long COVID causes substantial health burden globally, affecting ~30.6% of adults who have ever had symptomatic COVID-19. Despite this, long COVID remains overlooked in public health decision-making. We built a model and easy-to…
View article: Long-term immunogenicity of a single-dose live recombinant chimeric Japanese encephalitis vaccine in adults
Long-term immunogenicity of a single-dose live recombinant chimeric Japanese encephalitis vaccine in adults Open
Background Japanese encephalitis virus is a leading cause of viral encephalitis in Asia, with high case-fatality rate and morbidity. Although the live recombinant Japanese encephalitis chimeric vaccine (Imojev®) offers strong initial immun…
View article: Integrating post-validation surveillance of lymphatic filariasis with the WHO STEPwise approach to non-communicable disease risk factor surveillance in Niue, a study protocol
Integrating post-validation surveillance of lymphatic filariasis with the WHO STEPwise approach to non-communicable disease risk factor surveillance in Niue, a study protocol Open
Background Lymphatic filariasis (LF), a mosquito-borne parasitic disease caused by three species of filarial worms, was first detected in Niue, a small Pacific Island nation of approximately 1,600 people, in 1954. After extensive efforts i…
View article: Laboratory Comparison of Rapid Antigen Diagnostic Tests for Lymphatic Filariasis: STANDARD Q Filariasis Antigen Test (QFAT) Versus Bioline Filariasis Test Strip (FTS)
Laboratory Comparison of Rapid Antigen Diagnostic Tests for Lymphatic Filariasis: STANDARD Q Filariasis Antigen Test (QFAT) Versus Bioline Filariasis Test Strip (FTS) Open
Accurate rapid diagnostic tests (RDTs) are needed to diagnose lymphatic filariasis (LF) in global elimination programmes. We evaluated the performance of the new STANDARD Q Filariasis Antigen Test (QFAT) against the Bioline Filariasis Test…
View article: Integrated Serosurveillance of Infectious Diseases Using Multiplex Bead Assays: A Systematic Review
Integrated Serosurveillance of Infectious Diseases Using Multiplex Bead Assays: A Systematic Review Open
Integrated serological surveillance (serosurveillance) involves testing for antibodies to multiple pathogens (or species) simultaneously and can be achieved using multiplex bead assays (MBAs). This systematic review aims to describe pathog…