Claire Bertrand
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View article: Negative Affect Circuit Subtypes and Neural, Behavioral, and Affective Responses to MDMA
Negative Affect Circuit Subtypes and Neural, Behavioral, and Affective Responses to MDMA Open
Importance Rapidly acting therapeutics like 3,4-methylenedioxymethamphetamine (MDMA) are promising treatments for disorders such as posttraumatic stress disorder (PTSD). However, understanding who benefits most and the underlying neural me…
View article: A cognitive neural circuit biotype of depression showing functional and behavioral improvement after transcranial magnetic stimulation in the B-SMART-fMRI trial
A cognitive neural circuit biotype of depression showing functional and behavioral improvement after transcranial magnetic stimulation in the B-SMART-fMRI trial Open
View article: La technologie PROTAC
La technologie PROTAC Open
View article: Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS
Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS Open
The linear chromosome of Streptomyces exhibits a highly compartmentalized structure with a conserved central region flanked by variable arms. As double strand break (DSB) repair mechanisms play a crucial role in shaping the genome plastici…
View article: Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS
Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS Open
The linear chromosome of Streptomyces exhibits a highly compartmentalized structure with a conserved central region flanked by variable arms. As double strand break (DSB) repair mechanisms play a crucial role in shaping the genome plastici…
View article: Ketamine’s acute effects on negative brain states are mediated through distinct altered states of consciousness in humans
Ketamine’s acute effects on negative brain states are mediated through distinct altered states of consciousness in humans Open
Ketamine commonly and rapidly induces dissociative and other altered states of consciousness (ASCs) in humans. However, the neural mechanisms that contribute to these experiences remain unknown. We used functional neuroimaging to engage ke…
View article: Co-existence of negative and positive associations between cognition and intergenerational psychiatric symptoms reveal necessity of socioeconomic and clinical enrichment
Co-existence of negative and positive associations between cognition and intergenerational psychiatric symptoms reveal necessity of socioeconomic and clinical enrichment Open
Background Mental illnesses are a leading cause of disability globally. Across 17 psychiatric disorders, functional disability is often in part caused by cognitive impairments. However, cognitive heterogeneity in mental health is poorly un…
View article: Bacterial NHEJ: a never ending story
Bacterial NHEJ: a never ending story Open
Summary Double‐strand breaks (DSBs) are the most detrimental DNA damage encountered by bacterial cells. DBSs can be repaired by homologous recombination thanks to the availability of an intact DNA template or by Non‐Homologous End Joining …
View article: Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427
Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427 Open
The draft genome of Streptomyces sp. strain ETH9427 was sequenced and assembled into three large scaffolds, a 7.745-Mb linear chromosome with terminal inverted repeats of 201 kb and two probable extrachromosomal elements.
View article: Genome plasticity is governed by double strand break DNA repair in Streptomyces
Genome plasticity is governed by double strand break DNA repair in Streptomyces Open
The linear chromosome of the bacterium Streptomyces exhibits a remarkable genetic organization with grossly a central conserved region flanked by variable chromosomal arms. The terminal diversity co-locates with an intense DNA plasticity i…
View article: Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens
Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens Open
Non-homologous end-joining (NHEJ) is a double strand break (DSB) repair pathway which does not require any homologous template and can ligate two DNA ends together. The basic bacterial NHEJ machinery involves two partners: the Ku protein, …
View article: Construction of pDYN6902, a new Streptomyces integrative expression vector designed for cloning sequences interfering with Escherichia coli viability
Construction of pDYN6902, a new Streptomyces integrative expression vector designed for cloning sequences interfering with Escherichia coli viability Open
View article: Healthcare circuit and primary-care/hospital coordination: Study of an experiment conducted in Nancy, France aimed to reduce re-hospitalization of elderly patients at risk of hospitalization
Healthcare circuit and primary-care/hospital coordination: Study of an experiment conducted in Nancy, France aimed to reduce re-hospitalization of elderly patients at risk of hospitalization Open