Claire L. Gorrie
YOU?
Author Swipe
View article: Ciprofloxacin resistance in <i>Klebsiella pneumoniae</i>: phenotype prediction from genotype and global distribution of resistance determinants
Ciprofloxacin resistance in <i>Klebsiella pneumoniae</i>: phenotype prediction from genotype and global distribution of resistance determinants Open
BACKGROUND Ciprofloxacin resistant Klebsiella pneumoniae is common or emerging in many geographies, and knowledge of local resistance rates is important for empirical therapy. Whilst there are known K. pneumoniae ciprofloxacin resistance d…
View article: Benchmarking of tools for resolving plasmids from short-read assemblies for <i>Klebsiella pneumoniae</i>
Benchmarking of tools for resolving plasmids from short-read assemblies for <i>Klebsiella pneumoniae</i> Open
The critical role of plasmids, particularly in the dissemination of AMR and virulence in nosocomial pathogens like Klebsiella pneumoniae , underpins the need for robust and scalable tools for plasmid identification and reconstruction from …
View article: Global analysis of the genomic diversity, antimicrobial resistance and potential vaccine candidates carried by the major global bovine pathogen Streptococcus uberis
Global analysis of the genomic diversity, antimicrobial resistance and potential vaccine candidates carried by the major global bovine pathogen Streptococcus uberis Open
Streptococcus uberis is a leading cause of bovine mastitis, resulting in large economic losses and welfare issues for affected cows. However, relatively little is known about the global distribution and emergence of bovine mastitis-causing…
View article: Rapid, reference-free identification of bacterial pathogen transmission using optimized split k-mer analysis
Rapid, reference-free identification of bacterial pathogen transmission using optimized split k-mer analysis Open
Infections caused by multidrug-resistant organisms (MDROs) are difficult to treat and often life threatening and place a burden on the healthcare system. Minimizing the transmission of MDROs in hospitals is a global priority with genomics …
View article: Changes in isolation guidelines for CPE patients results in only mild reduction in required hospital beds
Changes in isolation guidelines for CPE patients results in only mild reduction in required hospital beds Open
Our analysis showed that while the changes result in modest savings in the need for dedicated isolation rooms, they could reduce the duration of time individual patients spend in isolation by up to three weeks. However, ongoing investments…
View article: Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin
Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin Open
View article: Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae
Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae Open
Interpreting the phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. Whilst all strains are expected to carry a chromosomal copy conferring resistance to ampicillin, they may also carry mutations in chromosomal bla S…
View article: Carbapenemase-producing enterobacterales colonisation status does not lead to more frequent admissions: a linked patient study
Carbapenemase-producing enterobacterales colonisation status does not lead to more frequent admissions: a linked patient study Open
Background Hospitals in any given region can be considered as part of a network, where facilities are connected to one another – and hospital pathogens potentially spread – through the movement of patients between them. We sought to descri…
View article: Diversity, functional classification and genotyping of SHV β-lactamases in<i>Klebsiella pneumoniae</i>
Diversity, functional classification and genotyping of SHV β-lactamases in<i>Klebsiella pneumoniae</i> Open
Interpreting phenotypes of bla SHV alleles in Klebsiella pneumoniae genomes is complex. While all strains are expected to carry a chromosomal copy conferring resistance to ampicillin, they may also carry mutations in chromosomal bla SHV al…
View article: Carbapenemase-producing Enterobacterales colonisation status does not lead to more frequent admissions: a linked patient study
Carbapenemase-producing Enterobacterales colonisation status does not lead to more frequent admissions: a linked patient study Open
Background Hospitals in any given region can be considered as part of a network, where facilities are connected to one another – and hospital pathogens potentially spread – through the movement of patients between them. We sought to descri…
View article: Comparison of contemporary invasive and non-invasive <i>Streptococcus pneumoniae</i> isolates reveals new insights into circulating anti-microbial resistance determinants
Comparison of contemporary invasive and non-invasive <i>Streptococcus pneumoniae</i> isolates reveals new insights into circulating anti-microbial resistance determinants Open
Streptococcus pneumoniae is a major human pathogen with a high burden of disease. Non-invasive isolates (those found in non-sterile sites) are thought to be a key source of invasive isolates (those found in sterile sites) and a reservoir o…
View article: Molecular and clinical epidemiology of carbapenem resistant Acinetobacter baumannii ST2 in Oceania: a multicountry cohort study
Molecular and clinical epidemiology of carbapenem resistant Acinetobacter baumannii ST2 in Oceania: a multicountry cohort study Open
View article: Population structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae causing invasive disease in Victoria, Australia
Population structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae causing invasive disease in Victoria, Australia Open
Streptococcus pneumoniae is a major human pathogen and can cause a range of conditions from asymptomatic colonization to invasive pneumococcal disease (IPD). The epidemiology and distribution of IPD-causing serotypes in Australia has under…
View article: Evaluating the role of asymptomatic throat carriage of Streptococcus pyogenes in impetigo transmission in remote Aboriginal communities in Northern Territory, Australia: a retrospective genomic analysis
Evaluating the role of asymptomatic throat carriage of Streptococcus pyogenes in impetigo transmission in remote Aboriginal communities in Northern Territory, Australia: a retrospective genomic analysis Open
Australian National Health and Medical Research Council.
View article: Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin
Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin Open
Multidrug-resistant bacterial pathogens like vancomycin-resistant Enterococcus faecium (VREfm) are a critical threat to human health. Daptomycin is a last-resort antibiotic for VREfm infections with a novel mode-of-action, but for which re…
View article: Hidden Resistances: How Routine Whole-Genome Sequencing Uncovered an Otherwise Undetected <i>bla</i> <sub>NDM-1</sub> Gene in Vibrio alginolyticus from Imported Seafood
Hidden Resistances: How Routine Whole-Genome Sequencing Uncovered an Otherwise Undetected <i>bla</i> <sub>NDM-1</sub> Gene in Vibrio alginolyticus from Imported Seafood Open
Carbapenems are last-line antimicrobials, vital for use in human medicine. Antimicrobial resistance determinants such as bla NDM (New Delhi metallo-β-lactamase producing) genes conferring resistance to the carbapenem class of antimicrobial…
View article: An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance
An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance Open
View article: Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen
Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen Open
View article: Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistance
Bridging the gap between bioinformatics and the clinical and public health microbiology laboratory: An ISO-accredited genomics workflow for antimicrobial resistance Open
Realising the promise of genomics to revolutionise routine AMR diagnosis and surveillance has been a long-standing challenge in clinical and public health microbiology. We have directly addressed this issue by creating and validating abrit…
View article: Multi-site implementation of whole genome sequencing for hospital infection control: A prospective genomic epidemiological analysis
Multi-site implementation of whole genome sequencing for hospital infection control: A prospective genomic epidemiological analysis Open
View article: Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection
Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection Open
View article: Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings
Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings Open
View article: Widespread <i>Streptococcus pyogenes</i> Transmission between Impetigo Lesions and Asymptomatic Throat Carriage in a Longitudinal Cohort from Remote Communities
Widespread <i>Streptococcus pyogenes</i> Transmission between Impetigo Lesions and Asymptomatic Throat Carriage in a Longitudinal Cohort from Remote Communities Open
View article: Molecular and Clinical Epidemiology of Carbapenem Resistant <i>Acinetobacter baumannii</i> ST2 in Oceania: A Multicountry Cohort Study
Molecular and Clinical Epidemiology of Carbapenem Resistant <i>Acinetobacter baumannii</i> ST2 in Oceania: A Multicountry Cohort Study Open
View article: Genomic dissection of the bacterial population underlying<i>Klebsiella pneumoniae</i>infections in hospital patients: insights into an opportunistic pathogen
Genomic dissection of the bacterial population underlying<i>Klebsiella pneumoniae</i>infections in hospital patients: insights into an opportunistic pathogen Open
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections, which are increasingly complicated by the presence of extended-spectrum beta-lactamases (ESBLs) and carbapenem resistance. We conducted a year-long p…
View article: Daptomycin Resistance Occurs Predominantly in vanA-Type Vancomycin-Resistant Enterococcus faecium in Australasia and Is Associated With Heterogeneous and Novel Mutations
Daptomycin Resistance Occurs Predominantly in vanA-Type Vancomycin-Resistant Enterococcus faecium in Australasia and Is Associated With Heterogeneous and Novel Mutations Open
Healthcare associated infections caused by vancomycin-resistant Enterococcus faecium (VREfm) have a major impact on health outcomes. VREfm is difficult to treat because of intrinsic and acquired resistance to many clinically used antimicro…
View article: Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis
Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis Open
Melbourne Genomics Health Alliance, and National Health and Medical Research Council of Australia.
View article: Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients
Genomic surveillance of antimicrobial resistant bacterial colonisation and infection in intensive care patients Open
View article: ICE volume 42 issue 5 Cover and Front matter
ICE volume 42 issue 5 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant Enterococcus
Genomic Insights Into Last-Line Antimicrobial Resistance in Multidrug-Resistant Staphylococcus and Vancomycin-Resistant Enterococcus Open
Multidrug-resistant Staphylococcus and vancomycin-resistant Enterococcus (VRE) are important human pathogens that are resistant to most clinical antibiotics. Treatment options are limited and often require the use of ‘last-line’ antimicrob…