Claire Lafay‐Chebassier
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View article: Efficacy and Safety of NFL-101 as a Smoking Cessation Therapy: A Randomized Phase II Clinical Trial CESTO2
Efficacy and Safety of NFL-101 as a Smoking Cessation Therapy: A Randomized Phase II Clinical Trial CESTO2 Open
Introduction Tobacco addiction remains a major public health challenge. Existing smoking cessation treatments require prolonged daily use with potentially poor adherence and reduced efficacy. Methods The phase II study was a multicenter, r…
View article: French‐Speaking Network of Pharmacogenetics (<scp>RNPGx</scp>) Recommendations for Clinical Use of Mavacamten
French‐Speaking Network of Pharmacogenetics (<span>RNPGx</span>) Recommendations for Clinical Use of Mavacamten Open
Mavacamten, the first drug in the class of β‐cardiac myosin modulator, is used for the treatment of patients with hypertrophic cardiomyopathy. This orally administered drug demonstrates wide interpatient variability in pharmacokinetics par…
View article: Drugs associated with reversible cerebral vasoconstriction syndrome: A pharmacovigilance study in vigiBase<sup>®</sup>
Drugs associated with reversible cerebral vasoconstriction syndrome: A pharmacovigilance study in vigiBase<sup>®</sup> Open
Background Data on drug-induced reversible cerebral vasoconstriction syndrome (RCVS) are scarce. We aimed to describe RCVS characteristics with drugs previously identified as associated with RCVS and investigate potential signals related t…
View article: Tobacco Images Choice and its Association With Craving and Dependence in People Who Smoke Cigarettes
Tobacco Images Choice and its Association With Craving and Dependence in People Who Smoke Cigarettes Open
Introduction Increased salience of drug-related cues over nondrug reinforcers can drive drug use and contribute to tobacco use disorder (TUD). An important scientific and clinical goal is to effectively measure this elevated drug-seeking b…
View article: Smokers with higher positive or negative urgency have lower rates of smoking cessation success 12 months after a quit attempt
Smokers with higher positive or negative urgency have lower rates of smoking cessation success 12 months after a quit attempt Open
View article: CNS volume 29 issue 2 Cover and Front matter
CNS volume 29 issue 2 Cover and Front matter Open
View article: Tobacco Images Choice and Its Association with Craving and Dependence in Cigarette Smokers
Tobacco Images Choice and Its Association with Craving and Dependence in Cigarette Smokers Open
Introduction: Increased salience of drug-related cues over non-drug reinforcers can drive drug use and contribute to tobacco use disorder (TUD). An important scientific and clinical goal is to effectively measure this elevated drug-seeking…
View article: Methods and applications in addiction psychiatry research: 2021
Methods and applications in addiction psychiatry research: 2021 Open
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View article: Duration of the effectiveness of nicotine electronic cigarettes on smoking cessation and reduction: Systematic review and meta-analysis
Duration of the effectiveness of nicotine electronic cigarettes on smoking cessation and reduction: Systematic review and meta-analysis Open
Background The success of pharmacotherapies for smoking cessation in real-life remains limited, with a significant number of long-term relapses. Despite first promising results, the duration of the effectiveness of electronic cigarettes is…
View article: Preliminary Evidence That the Short Allele of 5-HTTLPR Moderates the Association of Psychiatric Symptom Severity on Suicide Attempt: The Example in Obsessive-Compulsive Disorder
Preliminary Evidence That the Short Allele of 5-HTTLPR Moderates the Association of Psychiatric Symptom Severity on Suicide Attempt: The Example in Obsessive-Compulsive Disorder Open
Background The severity of symptoms represents an important source of distress in patients with a psychiatric disease. However, the extent to which this endogenous stress factor interacts with genetic vulnerability factors for predicting s…
View article: Patterns of use and safety of ibrutinib in real‐life practice
Patterns of use and safety of ibrutinib in real‐life practice Open
Aims To provide real‐life data on patterns of use and safety of ibrutinib. Methods A cohort study including all patients initiating ibrutinib between 21 November 2014 and 21 November 2018, and followed for 1 year was conducted. Patient cha…
View article: Toxicities associated with chemotherapy regimens containing a fluoropyrimidine: A real-life evaluation in France
Toxicities associated with chemotherapy regimens containing a fluoropyrimidine: A real-life evaluation in France Open
View article: Serious adverse effects occurring after chemotherapy: A general cancer registry‐based incidence survey
Serious adverse effects occurring after chemotherapy: A general cancer registry‐based incidence survey Open
Aims Pharmaco‐epidemiological surveys enable the frequency of serious adverse effects—and also the determining factors of their occurrence and seriousness—to be quantified. Few studies systematically gathering post‐chemotherapy adverse eff…
View article: Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial
Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial Open
View article: Éclairages sociologiques sur les conditions d’arrêt et de maintien de la pratique tabagique des volontaires d’un essai clinique
Éclairages sociologiques sur les conditions d’arrêt et de maintien de la pratique tabagique des volontaires d’un essai clinique Open
En 2017, 26,9 % des Français étaient des fumeurs réguliers ; parmi eux plus de la moitié déclaraient avoir envie d’arrêter (Pasquereau et al., 2018). Un échantillon de 37 volontaires d’un essai clinique visant à tester l’efficacité d’un mé…
View article: Association illogique nalméfène et opioïdes : analyse dans la base française de pharmacovigilance
Association illogique nalméfène et opioïdes : analyse dans la base française de pharmacovigilance Open
View article: Dépistage du déficit en dihydropyrimidine déshydrogénase (DPD) et sécurisation des chimiothérapies à base de fluoropyrimidines : mise au point et recommandations nationales du GPCO-Unicancer et du RNPGx
Dépistage du déficit en dihydropyrimidine déshydrogénase (DPD) et sécurisation des chimiothérapies à base de fluoropyrimidines : mise au point et recommandations nationales du GPCO-Unicancer et du RNPGx Open
Fluoropyrimidines (FU) are still the most prescribed anticancer drugs for the treatment of solid cancers. However, fluoropyrimidines cause severe toxicities in 10 to 40% of patients and toxic deaths in 0.2 to 0.8% of patients, resulting in…
View article: Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study
Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study Open
View article: Exposure to sucrose during periods of withdrawal does not reduce cocaine-seeking behavior in rats
Exposure to sucrose during periods of withdrawal does not reduce cocaine-seeking behavior in rats Open
Concomitant access to drugs of abuse and alternative rewards such as sucrose has been shown to decrease addiction-related behaviors in animals. Here we investigated whether access to sucrose during abstinence in contexts that are temporall…
View article: Statins Reduce the Risks of Relapse to Addiction in Rats
Statins Reduce the Risks of Relapse to Addiction in Rats Open