Claire Olingy
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View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs
Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs Open
CD8 + T cells drive anti-cancer immunity in response to antigen-presenting cells such as dendritic cells and subpopulations of monocytes and macrophages. While CD14 + classical monocytes modulate CD8 + T cell responses, the contributions o…
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: In Science Journals
In Science Journals Open
Highlights from the Science family of journals
View article: Single-cell immune profiling reveals long-term changes in myeloid cells and identifies a novel subset of CD9+ monocytes associated with COVID-19 hospitalization
Single-cell immune profiling reveals long-term changes in myeloid cells and identifies a novel subset of CD9+ monocytes associated with COVID-19 hospitalization Open
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in severe immune dysfunction, hospitalization, and death. Many patients also develop long-COVID-19, experiencin…
View article: CD33 Expression on Peripheral Blood Monocytes Predicts Efficacy of Anti-PD-1 Immunotherapy Against Non-Small Cell Lung Cancer
CD33 Expression on Peripheral Blood Monocytes Predicts Efficacy of Anti-PD-1 Immunotherapy Against Non-Small Cell Lung Cancer Open
Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related deaths globally. Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti-programmed cell death protein 1 (anti-PD-1) therapy now well-utilized…
View article: Analyzing immune response to engineered hydrogels by hierarchical clustering of inflammatory cell subsets
Analyzing immune response to engineered hydrogels by hierarchical clustering of inflammatory cell subsets Open
Understanding the immune response to hydrogel implantation is critical for the design of immunomodulatory biomaterials. To study the progression of inflammation around poly(ethylene glycol) hydrogels presenting Arg-Gly-Asp (RGD) peptides a…
View article: Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment
Integrated single-cell transcriptome analysis reveals heterogeneity of esophageal squamous cell carcinoma microenvironment Open
The tumor microenvironment is a highly complex ecosystem of diverse cell types, which shape cancer biology and impact the responsiveness to therapy. Here, we analyze the microenvironment of esophageal squamous cell carcinoma (ESCC) using s…
View article: Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss
Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss Open
Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits. While acute muscle injuries t…
View article: Combined protein and transcript single cell RNA sequencing in human peripheral blood mononuclear cells
Combined protein and transcript single cell RNA sequencing in human peripheral blood mononuclear cells Open
Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single cell (sc)RNA …
View article: Interplay of Monocytes and T Lymphocytes in COVID-19 Severity
Interplay of Monocytes and T Lymphocytes in COVID-19 Severity Open
The COVID-19 pandemic represents an ongoing global crisis that has already impacted over 13 million people. The responses of specific immune cell populations to the disease remain poorly defined, which hinders improvements in treatment and…