Clara Duran
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View article: Infections Associated with Intrathecal Baclofen Therapy: A Multicenter Case-Control Study
Infections Associated with Intrathecal Baclofen Therapy: A Multicenter Case-Control Study Open
ITB pump infections are rare in our experience but significantly associated with spinal cord injury, alcohol use, and prior infectious surgery. Early identification and appropriate management yield favorable outcomes. These findings suppor…
View article: Leading with Impact: The Relationship Between School Heads’ Multifactor Leadership Styles and Teachers’ Job Satisfaction in Public Secondary Schools
Leading with Impact: The Relationship Between School Heads’ Multifactor Leadership Styles and Teachers’ Job Satisfaction in Public Secondary Schools Open
This study examined the relationship of school heads’ leadership styles on teacher job satisfaction across 19 public secondary schools within the Department of Education (DepEd) Schools Division of Siquijor. Grounded in Bass’s Multifactor …
View article: Self-Concept and Mathematics Proficiency of College Students in Davao City
Self-Concept and Mathematics Proficiency of College Students in Davao City Open
Self-concept plays a crucial role in mathematics achievement by influencing students' attitudes and motivation. The purpose of this study was to determine which domain of self-concept significantly influenced the mathematics proficiency le…
View article: Prosthetic Joint Infections: A Systematic Review
Prosthetic Joint Infections: A Systematic Review Open
Background/Objectives: The optimal duration of antibiotic therapy, a cornerstone of PJI treatment, remains a topic of considerable debate, with current recommendations often based on limited evidence and expert consensus. Emerging evidence…
View article: Suppressive Antibiotic Therapy in Prosthetic Joint Infections: A Contemporary Overview
Suppressive Antibiotic Therapy in Prosthetic Joint Infections: A Contemporary Overview Open
The management of prosthetic joint infections (PJIs) poses significant challenges, requiring a multidisciplinary approach involving surgical, microbiological, and pharmacological expertise. Suppressive antibiotic therapy (SAT) has emerged …
View article: Correction: Pregnant women with mild COVID-19 followed in community setting by telemedicine, and factors associated with unfavorable outcome
Correction: Pregnant women with mild COVID-19 followed in community setting by telemedicine, and factors associated with unfavorable outcome Open
[This corrects the article DOI: 10.1371/journal.pone.0288845.].
View article: National Cohort of Compassionate Use of Meropenem–Vaborbactam: No Benefit over Meropenem for Pseudomonas aeruginosa
National Cohort of Compassionate Use of Meropenem–Vaborbactam: No Benefit over Meropenem for Pseudomonas aeruginosa Open
Background: Meropenem–vaborbactam (MEM-VAB) is a novel carbapenem-beta-lactamase-inhibitor combination that demonstrates activity against carbapenem-resistant (CR) Gram-negative bacteria, and more specifically KPC-producers, since vaborbac…
View article: Effectiveness of temocillin in treatment of non-urinary tract infections caused by ESBL-producing Enterobacterales and risk factors for failure
Effectiveness of temocillin in treatment of non-urinary tract infections caused by ESBL-producing Enterobacterales and risk factors for failure Open
Objectives To describe the real-life use of temocillin for non-urinary tract infections, to assess its effectiveness in infections caused by ESBL-producing Enterobacterales, and to identify risk factors for treatment failure. Method Retros…
View article: Prosthetic Joint Infections due to <i>Candida</i> Species: A Multicenter International Study
Prosthetic Joint Infections due to <i>Candida</i> Species: A Multicenter International Study Open
Background Prosthetic joint infection (PJI) caused by Candida spp is a severe complication of arthroplasty. We investigated the outcomes of Candida PJI. Methods This was a retrospective observational multinational study including patients …
View article: Should we, and how to, optimize cefiderocol administration during severe nosocomial pneumonia due to carbapenem-resistant Acinetobacter baumanii? A viewpoint
Should we, and how to, optimize cefiderocol administration during severe nosocomial pneumonia due to carbapenem-resistant Acinetobacter baumanii? A viewpoint Open
Further research is needed to determine the optimal cefiderocol dosage and administration (mono vs. dual therapy, continuous vs. intermittent infusion), in severe Acinetobacter baumannii nosocomial pneumonia.
View article: Digital health for remote home monitoring of patients with COVID-19 requiring oxygen: a cohort study and literature review
Digital health for remote home monitoring of patients with COVID-19 requiring oxygen: a cohort study and literature review Open
Background The clinical course and outcome of COVID-19 vary widely, from asymptomatic and mild to critical. Elderly patients and patients with comorbidities are at increased risk of respiratory failure and oxygen requirements. Due to the m…
View article: Pregnant women with mild COVID-19 followed in community setting by telemedicine, and factors associated with unfavorable outcome
Pregnant women with mild COVID-19 followed in community setting by telemedicine, and factors associated with unfavorable outcome Open
Objectives Few is known on pregnant women with mild COVID-19 managed in a community setting with a telemedicine solution, including their outcomes. The objective of this study is to evaluate the adverse fetal outcomes and hospitalization r…
View article: Real-life impact of respiratory panel PCR assay on antibiotic prescription in geriatric acute care in the pre-COVID-19 era
Real-life impact of respiratory panel PCR assay on antibiotic prescription in geriatric acute care in the pre-COVID-19 era Open
View article: Short Antibiotic Treatment Duration for Osteomyelitis Complicating Pressure Ulcers: A Quasi-experimental Study
Short Antibiotic Treatment Duration for Osteomyelitis Complicating Pressure Ulcers: A Quasi-experimental Study Open
Background Osteomyelitis-complicating pressure ulcers are frequent among patients with spinal cord injuries (SCIs), and the optimal management is unknown. In our referral center, the current management is debridement and flap coverage surg…
View article: Real-life temocillin use in Greater Paris area, effectiveness and risk factors for failure in infections caused by ESBL-producing Enterobacterales: a multicentre retrospective study
Real-life temocillin use in Greater Paris area, effectiveness and risk factors for failure in infections caused by ESBL-producing Enterobacterales: a multicentre retrospective study Open
Background Temocillin is a β-lactam that is not hydrolysed by ESBLs Objectives To describe the real-life use of temocillin, to assess its effectiveness in infections caused by ESBL-producing Enterobacterales, and to identify risk factors f…
View article: Antibiotic Consumption and Bacterial Resistance Rates in Hospitalized COVID-19 Patients: A Retrospective Study During the 3 First Surges
Antibiotic Consumption and Bacterial Resistance Rates in Hospitalized COVID-19 Patients: A Retrospective Study During the 3 First Surges Open
In our hospital, during COVID-19 pandemic, overall consumption of antibiotics increased during the three first surges, mainly due to ICU prescription However, antibiotic consumption decreased in the Infectious Diseases Department. Rates of…
View article: Arthritis Caused by <i>Nannizziopsis obscura</i>, France
Arthritis Caused by <i>Nannizziopsis obscura</i>, France Open
Nannizziopsis spp., fungi responsible for emerging diseases, are rarely involved in human bone and joint infections. We present a rare case of septic arthritis with necrotizing cellulitis caused by N. obscura in a patient in France who had…
View article: Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study
Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study Open
View article: Impact of Omicron surge in community setting in greater Paris area
Impact of Omicron surge in community setting in greater Paris area Open
View article: Hyaluronic Acid and Chondroitin Sulphate Treatment for Recurrent Severe Urinary Tract Infections due to Multidrug-Resistant Gram-Negative Bacilli in a Patient With Multiple Sclerosis: Case Report and Literature Review
Hyaluronic Acid and Chondroitin Sulphate Treatment for Recurrent Severe Urinary Tract Infections due to Multidrug-Resistant Gram-Negative Bacilli in a Patient With Multiple Sclerosis: Case Report and Literature Review Open
Urinary tract infections (UTIs) are the most common bacterial infections in patients with neurogenic lower urinary tract dysfunction. Antibiotic options for prophylaxis or curative treatment in case of recurrent UTIs, especially due to mul…
View article: Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
Gut microbiome signatures linked to HIV-1 reservoir size and viremia control Open
View article: Additional file 4 of Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
Additional file 4 of Gut microbiome signatures linked to HIV-1 reservoir size and viremia control Open
Additional file 3: Table S1. List of differentially expressed genes between controllers and non-controllers at baseline (adjusted p-value <0.1and log2 FoldChange = 0). Table S2. Detailed information of differentially expressed genes (DEGs)…
View article: Additional file 3 of Gut microbiome signatures linked to HIV-1 reservoir size and viremia control
Additional file 3 of Gut microbiome signatures linked to HIV-1 reservoir size and viremia control Open
Additional file 2: Dataset S1. Longitudinal microbial composition (relative abundance) in viremic controllers and non-controllers analyzed by MetaPhlAn2.0. Dataset S2. Raw bacterial protein counts at baseline in viremic controllers and non…
View article: Teaching Practices in Secondary Schools’ Online Learning during Pandemic Times
Teaching Practices in Secondary Schools’ Online Learning during Pandemic Times Open
The COVID 19 pandemic challenges the economy as well as education. Teachers have to be creative and innovative in their strategies as they migrate from face-to-face to online. Practices need to be adaptive to a situation where the students…
View article: Factors Associated With Treatment Failure in Moderately Severe Community-Acquired Pneumonia
Factors Associated With Treatment Failure in Moderately Severe Community-Acquired Pneumonia Open
In this secondary analysis of a randomized clinical trial, among patients with CAP who reached clinical stability after 3 days of antibiotic treatment, only male sex and age were associated with higher risk of failure, independent of antib…
View article: Gut Microbiome Signatures Linked to HIV-1 Reservoir Size and Viremia Control
Gut Microbiome Signatures Linked to HIV-1 Reservoir Size and Viremia Control Open
Background The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen wit…
View article: Time to resolution of respiratory and systemic coronavirus disease 2019 symptoms in community setting
Time to resolution of respiratory and systemic coronavirus disease 2019 symptoms in community setting Open
View article: ACCESS-Background rate of adverse events-definition – Generalized Convulsions
ACCESS-Background rate of adverse events-definition – Generalized Convulsions Open
This document contains the definition of Generalized Convulsions and the operationalization to extract this event from different electronic health care databases in the EU, to calculate background rates of AESI The documen…
View article: Dalbavancin treatment for prosthetic joint infections in real-life: a national cohort study and literature review
Dalbavancin treatment for prosthetic joint infections in real-life: a national cohort study and literature review Open
View article: Rôle de la pharmacie dans l’investigation allergologique des patients ayant présenté un exanthème en cours d’hospitalisation pour COVID-19
Rôle de la pharmacie dans l’investigation allergologique des patients ayant présenté un exanthème en cours d’hospitalisation pour COVID-19 Open