Clara Inghelram
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View article: Primed for degradation: How weak protein interactions enable molecular glue degraders
Primed for degradation: How weak protein interactions enable molecular glue degraders Open
Molecular glues are small drug-like molecules that induce de novo protein-protein interactions or facilitate pre-existing weak interactions between proteins. In the context of a ubiquitin ligase, such binding events frequently result in ub…
View article: Specific protein-RNA interactions are mostly preserved in biomolecular condensates
Specific protein-RNA interactions are mostly preserved in biomolecular condensates Open
Many biomolecular condensates are enriched in and depend on RNAs and RNA binding proteins (RBPs). So far, only a few studies have addressed the characterization of the intermolecular interactions responsible for liquid-liquid phase separat…