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View article: Sickness absences and losses in productivity-adjusted life years before, during and after the most common orthopedic surgical procedures among employed individuals in Finland
Sickness absences and losses in productivity-adjusted life years before, during and after the most common orthopedic surgical procedures among employed individuals in Finland Open
View article: The next decade of cardiovascular disease burden in Qatar, a gulf cooperation council country: Projections from 2024 to 2033
The next decade of cardiovascular disease burden in Qatar, a gulf cooperation council country: Projections from 2024 to 2033 Open
This study offers valuable insights into the projected burden of CVD in Qatar, highlighting the need for effective preventive strategies to reduce risk.
View article: 3556 Changes in health-related quality of life, mood, and work productivity after first seizure events
3556 Changes in health-related quality of life, mood, and work productivity after first seizure events Open
View article: Scoping Review of Productivity-Adjusted Life Years (PALYs): Methods, Applications and Policy Implications
Scoping Review of Productivity-Adjusted Life Years (PALYs): Methods, Applications and Policy Implications Open
PALYs have been utilised in diverse diseases and contexts, highlighting their utility in measuring societal health impacts. However, adding unpaid and informal work makes burden estimates more accurate. The increasing emphasis on preventio…
View article: Productivity Losses Due to Long-Term Back Problems in Working-Age Australians
Productivity Losses Due to Long-Term Back Problems in Working-Age Australians Open
Importance Long-term back problems impact an individual’s ability to participate in the workforce productively, potentially resulting in financial stress and furthering inequities. Estimates of future productivity losses could inform advoc…
View article: Discontinuation of lipid-modifying agents and failure to achieve target LDL cholesterol levels across cardiovascular risk groups
Discontinuation of lipid-modifying agents and failure to achieve target LDL cholesterol levels across cardiovascular risk groups Open
Long-term adherence to LMAs remains a challenge, particularly in low-risk. Target achievement was poor, highlighting gaps in therapeutic optimization, patient engagement, and monitoring.
View article: Comparative risk of major health events among individuals prescribed different antiseizure medications following ischemic stroke
Comparative risk of major health events among individuals prescribed different antiseizure medications following ischemic stroke Open
Objective The aim of this study was to compare the risk of seizure, recurrent stroke, fall or fracture, and mortality in individuals prescribed different antiseizure medications (ASMs) following an ischemic stroke. Methods We identified al…
View article: OP22 Productivity Benefits Of Modifying Cardiovascular Disease Risk In Type 2 Diabetes In Australia: A 10-Year Prediction Dynamic Model
OP22 Productivity Benefits Of Modifying Cardiovascular Disease Risk In Type 2 Diabetes In Australia: A 10-Year Prediction Dynamic Model Open
Introduction Diabetes has been shown to influence the individual’s work productivity in terms of both presenteeism (reduced productivity while at work) and absenteeism (absence from work because of illness). We sought to estimate the poten…
View article: OD19 Future Health And Economic Burden Of Cardiovascular Disease In Type 2 Diabetes In Qatar, From 2023 To 2032
OD19 Future Health And Economic Burden Of Cardiovascular Disease In Type 2 Diabetes In Qatar, From 2023 To 2032 Open
Introduction The Middle East and North Africa region accounts for the largest prevalence of type 2 diabetes (T2D). Qatar ranks top 10 for global T2D prevalence, with 17 percent in 2022. Also, 50 to 70 percent of the cardiovascular events o…
View article: OD17 Future Health And Economic Burden Of Cardiovascular Disease In Type 2 Diabetes In Australia From 2021 To 2031
OD17 Future Health And Economic Burden Of Cardiovascular Disease In Type 2 Diabetes In Australia From 2021 To 2031 Open
Introduction Diabetes is a key risk factor for cardiovascular disease (CVD), with a two-to-four-times higher risk than that in non-diabetes. The health burden associated with CVD imposes a major economic concern on healthcare systems and o…
View article: PP01 Early Health Technology Assessments Of Health And Well-Being Returns On Investment In The Biobanks
PP01 Early Health Technology Assessments Of Health And Well-Being Returns On Investment In The Biobanks Open
Introduction Human tissue biobanks provide vital infrastructure to support both basic science and clinical research, but their economic value in terms of attributable population health gains is unclear. We evaluated the population health r…
View article: Cost-effectiveness of lowering systolic blood pressure in reducing cardiovascular disease burden in Australia
Cost-effectiveness of lowering systolic blood pressure in reducing cardiovascular disease burden in Australia Open
Our results demonstrate that reducing SBP at the population level is cost-saving and has a significant positive impact on cardiovascular outcomes and related costs for those at risk of CVD.
View article: The reduction of the productivity burden of cardiovascular disease by improving the risk factor control Among Australians with type 2 diabetes: a 10-year dynamic analysis
The reduction of the productivity burden of cardiovascular disease by improving the risk factor control Among Australians with type 2 diabetes: a 10-year dynamic analysis Open
Aims To quantify the productivity burden of cardiovascular disease (CVD) in type 2 diabetes and the potential benefits of improved CVD risk factor control. Methods and results We designed models to quantify the productivity burden (using t…
View article: Effect of Oral Bisphosphonate Drug Holiday on Mortality Following Hip Fracture
Effect of Oral Bisphosphonate Drug Holiday on Mortality Following Hip Fracture Open
Context Current clinical guidelines recommend a drug holiday after extended use of oral bisphosphonates. However, no studies have investigated the effect of drug holidays before hip fractures on postfracture mortality. Objective This work …
View article: Redox Regulation of LAT Enhances T Cell-Mediated Inflammation
Redox Regulation of LAT Enhances T Cell-Mediated Inflammation Open
The positional cloning of single nucleotide polymorphisms (SNPs) of the neutrophil cytosolic factor 1 (Ncf1) gene, advocating that a low oxidative burst drives autoimmune disease, demands an understanding of the underlying molecular causes…
View article: Work productivity, quality of life, and care needs: An unfolding epilepsy burden revealed in the Australian Epilepsy Project pilot study
Work productivity, quality of life, and care needs: An unfolding epilepsy burden revealed in the Australian Epilepsy Project pilot study Open
Objective Epilepsy is a common and serious neurological disorder. This cross‐sectional analysis addresses the burden of epilepsy at different stages of the disease. Methods This pilot study is embedded within the Australian Epilepsy Projec…
View article: Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review
Cost-Effectiveness of Screening Strategies for Familial Hypercholesterolaemia: An Updated Systematic Review Open
View article: Redox Regulation of Lat Enhances T Cell-Mediated Inflammation
Redox Regulation of Lat Enhances T Cell-Mediated Inflammation Open
View article: Combined population genomic screening for three high-risk conditions in Australia: a modelling study
Combined population genomic screening for three high-risk conditions in Australia: a modelling study Open
Australian Government, Department of Health, Medical Research Future Fund, Genomics Health Futures Mission (APP2009024). National Heart Foundation Future Leader Fellowship (102604).
View article: Early lowering of LDL-C is a more cost-effective strategy than lowering LDL-C later in life: a cost-effectiveness analysis using Mendelian Randomisation
Early lowering of LDL-C is a more cost-effective strategy than lowering LDL-C later in life: a cost-effectiveness analysis using Mendelian Randomisation Open
Background Early control of low-density lipoprotein-cholesterol (LDL-C) is an effective way to reduce the risk of coronary heart disease (CHD). However, a comprehensive assessment of cost-effectiveness of different lipid-lowering strategie…
View article: Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A <scp>10</scp> ‐year forecasting model
Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A <span>10</span> ‐year forecasting model Open
Aims To predict the future health and economic burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) in Qatar. Materials and Methods A dynamic multistate model was designed to simulate the progression of fatal and non‐fatal CVD e…
View article: Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors
Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors Open
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coronary ath…
View article: Lipid-Lowering Strategies for Primary Prevention of Coronary Heart Disease in the UK: A Cost-Effectiveness Analysis
Lipid-Lowering Strategies for Primary Prevention of Coronary Heart Disease in the UK: A Cost-Effectiveness Analysis Open
View article: Shift from older‐ to newer‐generation antiseizure medications in people with acute ischemic stroke in Australia: A population‐based study
Shift from older‐ to newer‐generation antiseizure medications in people with acute ischemic stroke in Australia: A population‐based study Open
Objective To investigate the trends in antiseizure medications (ASMs) use following ischemic stroke and to examine factors associated with use of newer‐ and older‐generation ASMs. Methods A retrospective cohort study was conducted using st…
View article: Calling for Urgent Actions to Improve Lipid Management in Australia–Low Medication Adherence and Poor Therapeutic Goal Attainment Lead to Poor Outcomes and Wasted Resources
Calling for Urgent Actions to Improve Lipid Management in Australia–Low Medication Adherence and Poor Therapeutic Goal Attainment Lead to Poor Outcomes and Wasted Resources Open
View article: Table of Contents
Table of Contents Open
View article: Correction to: Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
Correction to: Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study Open
View article: Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study
Hip fracture incidence and post-fracture mortality in Victoria, Australia: a state-wide cohort study Open
View article: Enhancing the Detection and Care of Heterozygous Familial Hypercholesterolemia in Primary Care: Cost-Effectiveness and Return on Investment
Enhancing the Detection and Care of Heterozygous Familial Hypercholesterolemia in Primary Care: Cost-Effectiveness and Return on Investment Open
Background: Heterozygous familial hypercholesterolemia (HeFH) is under-detected and undertreated. A general practitioner-led screening and care program for HeFH effectively identified and managed patients with HeFH. We evaluated the cost-e…
View article: Table of Contents
Table of Contents Open