Clarissa Klein
YOU?
Author Swipe
View article: Integrating Pharmacogenomics into the Broader Construct of Genomic Medicine: Efforts by the ClinGen Pharmacogenomics Working Group (PGxWG)
Integrating Pharmacogenomics into the Broader Construct of Genomic Medicine: Efforts by the ClinGen Pharmacogenomics Working Group (PGxWG) Open
Pharmacogenomics (PGx) is focused on the relationship between an individual's genetic makeup and their response to medications, with the overarching aim of guiding prescribing decisions to improve drug efficacy and reduce adverse events. T…
View article: P220: The ClinGen Variant Curation Interface (VCI) to support direct submission and tracking of submissions to ClinVar
P220: The ClinGen Variant Curation Interface (VCI) to support direct submission and tracking of submissions to ClinVar Open
View article: P179: The ClinGen Pharmacogenomics Working Group: Developing frameworks for evaluating pharmacogenomic gene validity and actionability
P179: The ClinGen Pharmacogenomics Working Group: Developing frameworks for evaluating pharmacogenomic gene validity and actionability Open
Pharmacogenomics (PGx) is a rapidly advancing field that studies the relationship between an individual's genetic makeup and their response to medications, with goals to guide prescribing decisions to prevent toxicity and improve drug effi…
View article: P826: Evaluating HLA allele-disease associations in ClinGen: Development of a new curation tool
P826: Evaluating HLA allele-disease associations in ClinGen: Development of a new curation tool Open
The Human Leukocyte Antigen (HLA) region, located on the short arm of chromosome 6, is the most complex and polymorphic region in the human genome. This region's high structural and genetic diversity is the result of natural selection for …
View article: P178: The ClinGen Pharmacogenomics Working Group: Developing a framework for gene-drug response clinical validity
P178: The ClinGen Pharmacogenomics Working Group: Developing a framework for gene-drug response clinical validity Open
View article: P673: Batch ClinVar submission support in ClinGen’s Variant Curation Interface (VCI)
P673: Batch ClinVar submission support in ClinGen’s Variant Curation Interface (VCI) Open
View article: Verifikation potentieller Interaktionspartner des Zellzyklusregulators p27Kip1
Verifikation potentieller Interaktionspartner des Zellzyklusregulators p27Kip1 Open
p27Kip1 spielt als Inhibitor der Cyclinabhängigen Kinasen (CKI) eine wichtige Rolle in der Regulation des Zellzyklusses, aber auch in der Steuerung von Apoptose und Migration und der Ausbildung der Polarität. Fehlfunktionen und -regulation…