Clasine M. de Klerk
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View article: An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles
An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles Open
Objective New screening tests for colorectal cancer (CRC) are rapidly emerging. Conducting trials with mortality reduction as the end point supporting their adoption is challenging. We re-examined the principles underlying evaluation of ne…
View article: Urban density differences in colorectal cancer screening participation and screening yield in The Netherlands
Urban density differences in colorectal cancer screening participation and screening yield in The Netherlands Open
Lower socioeconomic status has been associated with higher colorectal cancer incidence and lower participation in population-based screening with faecal immunochemical testing (FIT) but regional variations in participation may also exist. …
View article: Performance of two faecal immunochemical tests for the detection of advanced neoplasia at different positivity thresholds: a cross-sectional study of the Dutch national colorectal cancer screening programme
Performance of two faecal immunochemical tests for the detection of advanced neoplasia at different positivity thresholds: a cross-sectional study of the Dutch national colorectal cancer screening programme Open
View article: Participant-Related Risk Factors for False-Positive and False-Negative Fecal Immunochemical Tests in Colorectal Cancer Screening: Systematic Review and Meta-Analysis
Participant-Related Risk Factors for False-Positive and False-Negative Fecal Immunochemical Tests in Colorectal Cancer Screening: Systematic Review and Meta-Analysis Open
Multiple risk factors, known at time of FIT invitation, are associated with false FIT results in CRC screening. This information can be used to identify populations risking false reassurance after a negative result or unnecessary colonosco…
View article: A large proportion of fecal immunochemical test-positive participants in colorectal cancer screening is symptomatic
A large proportion of fecal immunochemical test-positive participants in colorectal cancer screening is symptomatic Open
Background Symptomatic invitees are advised not to participate in colorectal cancer (CRC) screening but to directly consult their general practitioner (GP), because fecal immunochemical test (FIT) sensitivity for cancer is not optimal. Thi…