Claudia Bonechi
YOU?
Author Swipe
View article: Geographical Origin Authentication of Leaves and Drupes from Olea europaea via 1H NMR and Excitation–Emission Fluorescence Spectroscopy: A Data Fusion Approach
Geographical Origin Authentication of Leaves and Drupes from Olea europaea via 1H NMR and Excitation–Emission Fluorescence Spectroscopy: A Data Fusion Approach Open
Geographical origin authentication of agrifood products is essential for ensuring their quality, preventing fraud, and maintaining consumers’ trust. In this study, we used proton nuclear magnetic resonance (1H NMR) and excitation–emission …
View article: Synthesis and Reactivity of Oligo(ethylene glycol)-Tethered Morita–Baylis–Hillman Dimers in the Formation of Macrocyclic Structures Showing Remarkable Cytotoxicity
Synthesis and Reactivity of Oligo(ethylene glycol)-Tethered Morita–Baylis–Hillman Dimers in the Formation of Macrocyclic Structures Showing Remarkable Cytotoxicity Open
Background/Objectives: Crown ethers have received increasing interest owing to their ability to form stable complexes with cations. This molecular feature has been successfully exploited in the development of biologically relevant ionophor…
View article: Cationic liposomes as carriers of natural compounds from plant extract
Cationic liposomes as carriers of natural compounds from plant extract Open
Lipid-based nanocarriers provide versatile platforms for the encapsulation and delivery of many different bioactive compounds to improve the solubility, stability and therapeutic efficacy of bioactive phyto-compounds. In this study, liposo…
View article: Crosslinking by Click Chemistry of Hyaluronan Graft Copolymers Involving Resorcinol-Based Cinnamate Derivatives Leading to Gel-like Materials
Crosslinking by Click Chemistry of Hyaluronan Graft Copolymers Involving Resorcinol-Based Cinnamate Derivatives Leading to Gel-like Materials Open
The well-known “click chemistry” reaction copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (CuAAC) was used to transform under very mild conditions hyaluronan-based graft copolymers HA(270)-FA-Pg into the crosslinked derivatives …
View article: Effect of Mild Conditions on PVA-Based Theta Gel Preparation: Thermal and Rheological Characterization
Effect of Mild Conditions on PVA-Based Theta Gel Preparation: Thermal and Rheological Characterization Open
Polyvinyl alcohol (PVA), possessing a strong ability to form hydrogels, has been widely used for various pharmaceutical and biomedical applications. In particular, the use of PVA-PEG in the form of theta gels for altered cartilage treatmen…
View article: Analysis of the utility of a rapid vesicle isolation method for clinical strains of <i>Pseudomonas aeruginosa</i>
Analysis of the utility of a rapid vesicle isolation method for clinical strains of <i>Pseudomonas aeruginosa</i> Open
Pseudomonas aeruginosa , a pathogen capable of causing diseases ranging from mild to life-threatening, has a large arsenal of virulence factors. Notably, extracellular vesicles have emerged as significant players in the pathogenesis of thi…
View article: Reactivity of a Morita–Baylis–Hillman Adduct Derivative Bearing a Triphenylamine Moiety with Lysine Models
Reactivity of a Morita–Baylis–Hillman Adduct Derivative Bearing a Triphenylamine Moiety with Lysine Models Open
The reactivity of Morita–Baylis–Hillman Adduct (MBHA) derivative 7 was studied with different primary amine derivatives such as n ‐butylamine, Nα‐acetyl‐ L ‐lysine methyl ester, and a poly‐( L ‐lysine) derivative as lysine models to obtain…
View article: Physiochemical Characterization of Lipidic Nanoformulations Encapsulating the Antifungal Drug Natamycin
Physiochemical Characterization of Lipidic Nanoformulations Encapsulating the Antifungal Drug Natamycin Open
Natamycin is a tetraene polyene that exploits its antifungal properties by irreversibly binding components of fungal cell walls, blocking the growth of infections. However, topical ocular treatments with natamycin require frequent applicat…
View article: In Vitro Effects of Charged and Zwitterionic Liposomes on Human Spermatozoa and Supplementation with Liposomes and Chlorogenic Acid during Sperm Freezing
In Vitro Effects of Charged and Zwitterionic Liposomes on Human Spermatozoa and Supplementation with Liposomes and Chlorogenic Acid during Sperm Freezing Open
Semen handling and cryopreservation induce oxidative stress that should be minimized. In this study, human semen was supplemented during cryopreservation with formulations of handmade liposomes and chlorogenic acid (CGA), an antioxidant co…
View article: A Facile Access to Green Fluorescent Albumin Derivatives
A Facile Access to Green Fluorescent Albumin Derivatives Open
A Morita‐Baylis‐Hillman Adduct (MBHA) derivative bearing a triphenylamine moiety was found to react with human serum albumin ( HSA ) shifting its emission from the blue to the green‐yellow thus leading to green fluorescent albumin ( GFA ) …
View article: Cross-Linked Hyaluronan Derivatives in the Delivery of Phycocyanin
Cross-Linked Hyaluronan Derivatives in the Delivery of Phycocyanin Open
An easy and viable crosslinking technology, based on the “click-chemistry” reaction copper(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition (click-crosslinking), was applied to graft copolymers of medium molecular weight (i.e., 270 kDa)…
View article: Effect of Annurca Apple Extract on Anti-hyper Cholesterol Action of a RYR based Formulation
Effect of Annurca Apple Extract on Anti-hyper Cholesterol Action of a RYR based Formulation Open
Recently, European Authorities imposed that any product for daily consumption shall provide less than 3 mg of monacolins from red yeast rice (RYR). This obliges to find new formulations able to guarantee an effect on cholesterol levels clo…
View article: CCDC 2286050: Experimental Crystal Structure Determination
CCDC 2286050: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Liposomal Encapsulation of Citicoline for Ocular Drug Delivery
Liposomal Encapsulation of Citicoline for Ocular Drug Delivery Open
Glaucoma represents a group of neurodegenerative diseases characterized by optic nerve damage and the slowly progressive death of retinal ganglion cells. Glaucoma is considered the second leading cause of irreversible blindness worldwide. …
View article: Green Hydrogels Loaded with Extracts from Solanaceae for the Controlled Disinfection of Agricultural Soils
Green Hydrogels Loaded with Extracts from Solanaceae for the Controlled Disinfection of Agricultural Soils Open
The UN 2030 Agenda for Sustainable Development established the goal of cutting the use of pesticides in the EU by 50% by 2030. However, a ban on pesticides could seriously affect the productivity of agriculture, resulting in severe issues …
View article: Design and Optimization of Solid Lipid Nanoparticles Loaded with Triamcinolone Acetonide
Design and Optimization of Solid Lipid Nanoparticles Loaded with Triamcinolone Acetonide Open
Principles of quality by design and design of experiments are acquiring more importance in the discovery and application of new drug carriers, such as solid lipid nanoparticles. In this work, an optimized synthesis of solid lipid nanoparti…
View article: CCDC 2213739: Experimental Crystal Structure Determination
CCDC 2213739: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Spontaneous polymerization of benzofulvene monomers bearing a 4-Pyridylacetylene substituent in different positions of the benzofulvene scaffold
Spontaneous polymerization of benzofulvene monomers bearing a 4-Pyridylacetylene substituent in different positions of the benzofulvene scaffold Open
Two benzofulvene derivatives bearing a 4-pyridylacetylene substituent in different positions (i. e. 2 and 6) of the benzofulvene scaffold are designed and synthesized to evaluate the effects on the spontaneous solid-state polymerization of…
View article: Effects and Mechanisms Activated by Treatment with Cationic, Anionic and Zwitterionic Liposomes on an In Vitro Model of Porcine Pre-Pubertal Sertoli Cells
Effects and Mechanisms Activated by Treatment with Cationic, Anionic and Zwitterionic Liposomes on an In Vitro Model of Porcine Pre-Pubertal Sertoli Cells Open
Liposomes have been successfully used as drug-delivery vehicles, but there are no clinical studies on improved fertility and the few reported experimental studies have been performed in animal models far from humans. The aim of this paper …
View article: A tri(ethylene glycol)-tethered Morita–Baylis–Hillman dimer in the formation of macrocyclic crown ether-paracyclophane hybrid structures
A tri(ethylene glycol)-tethered Morita–Baylis–Hillman dimer in the formation of macrocyclic crown ether-paracyclophane hybrid structures Open
A tri(ethylene glycol)-tethered MBHA dimer was synthesized and found to react with n -butylamine leading to the formation of macrocyclic crown ether-paracyclophane hybrid structures that could be modulated by light.
View article: Characterization of Extracts of Coffee Leaves (Coffea arabica L.) by Spectroscopic and Chromatographic/Spectrometric Techniques
Characterization of Extracts of Coffee Leaves (Coffea arabica L.) by Spectroscopic and Chromatographic/Spectrometric Techniques Open
Coffea arabica L. leaves represent a viable alternative to the canonical matrices used for preparation of beverages, such as tea leaves and grounded coffee beans. Coffee leaves infusions are rich in antioxidant phenolic compounds and have …
View article: Design, Synthesis and Characterization of a Visible‐Light‐Sensitive Molecular Switch and Its PEGylation Towards a Self‐Assembling Molecule
Design, Synthesis and Characterization of a Visible‐Light‐Sensitive Molecular Switch and Its PEGylation Towards a Self‐Assembling Molecule Open
HBDI‐like chromophores represent a novel set of biomimetic switches mimicking the fluorophore of the green fluorescent protein that are currently studied with the hope to expand the molecular switch/motor toolbox. However, until now member…
View article: Effect of Flaking and Precooking Procedures on Antioxidant Potential of Selected Ancient Cereal and Legume Flours
Effect of Flaking and Precooking Procedures on Antioxidant Potential of Selected Ancient Cereal and Legume Flours Open
Consumption of cereals (and particularly ancient cereals) is considered the base of a healthy diet, and all current dietary guidelines have cereals at the bottom of the nutrition pyramid. Together with cereals, legumes are an excellent sou…
View article: Click-Chemistry Cross-Linking of Hyaluronan Graft Copolymers
Click-Chemistry Cross-Linking of Hyaluronan Graft Copolymers Open
An easy and viable crosslinking procedure by click-chemistry (click-crosslinking) of hyaluronic acid (HA) was developed. In particular, the clickable propargyl groups of hyaluronane-based HA-FA-Pg graft copolymers showing low and medium mo…
View article: Physicochemical Characterization of Hyaluronic Acid and Chitosan Liposome Coatings
Physicochemical Characterization of Hyaluronic Acid and Chitosan Liposome Coatings Open
Hyaluronic acid (HA) and chitosan (CH) are biopolymers that are widely used in many biomedical applications and for cosmetic purposes. Their chemical properties are fundamental to them working as drug delivery systems and improving their s…