Claudine Deloménie
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View article: Long-Circulating Liposomes Codelivering Amphotericin B and Retinoic Acid for Cutaneous Leishmaniasis Treatment
Long-Circulating Liposomes Codelivering Amphotericin B and Retinoic Acid for Cutaneous Leishmaniasis Treatment Open
Leishmaniasis is a neglected tropical disease that mainly affects socially vulnerable populations. It is caused by various Leishmania species, and manifests primarily as cutaneous (CL) or visceral leishmaniasis (VL). AmBisome, a com…
View article: Deciphering the role of polyethylene glycol-lipid anchors in siRNA-LNP efficacy for P2y2 inhibition in bone marrow-derived macrophages
Deciphering the role of polyethylene glycol-lipid anchors in siRNA-LNP efficacy for P2y2 inhibition in bone marrow-derived macrophages Open
Macrophages play a vital role in controlling tissue homeostasis, yet their dysregulation can drive the pathogenesis of various diseases. In this context, P2Y2, a purinergic receptor that binds ATP, could be involved in several biological m…
View article: Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury
Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury Open
This study investigates the potential of pulmonary delivery of siRNA as an emergency therapy for acute lung injury (ALI). To obtain a quick anti‐inflammatory response, TNF‐α, a critical pro‐inflammatory cytokine, is knocked down for its ea…
View article: Multicellular tumor spheroid model to study the multifaceted role of tumor-associated macrophages in PDAC
Multicellular tumor spheroid model to study the multifaceted role of tumor-associated macrophages in PDAC Open
View article: Cover Image, Volume 33, Issue 10
Cover Image, Volume 33, Issue 10 Open
The cover image is based on the Research Article A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin by Indira Mendez-David et al., https://doi.org/10.1002/hipo.2356…
View article: Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse
Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse Open
The beta-adrenergic system is a potent stimulus for enhancing cardiac output that may become deleterious when energy metabolism is compromised as in heart failure. We thus examined whether the AMP-activated protein kinase (AMPK) that is ac…
View article: A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin
A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin Open
We investigated the mechanisms underlying the effects of the antidepressant fluoxetine on behavior and adult hippocampal neurogenesis (AHN). After confirming our earlier report that the signaling molecule β‐arrestin‐2 (β‐Arr2) is required …
View article: The Inflammatory Response in Human Keratinocytes Exposed to Cinnamaldehyde Is Regulated by Nrf2
The Inflammatory Response in Human Keratinocytes Exposed to Cinnamaldehyde Is Regulated by Nrf2 Open
Keratinocytes (KC) play a crucial role in epidermal barrier function, notably through their metabolic activity and the detection of danger signals. Chemical sensitizers are known to activate the transcription factor nuclear factor (erythro…
View article: Vitamin C–squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Vitamin C–squalene bioconjugate promotes epidermal thickening and collagen production in human skin Open
View article: A non-linear relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin
A non-linear relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin Open
We investigated the mechanisms underlying the effects of the antidepressant fluoxetine on behavior and adult hippocampal neurogenesis (AHN). After confirming our earlier report that the signaling molecule β2-arrestin is required for the an…
View article: A Non-Linear Relation between Levels of Adult Hippocampal Neurogenesis and Expression of the Immature Neuron Marker Doublecortin
A Non-Linear Relation between Levels of Adult Hippocampal Neurogenesis and Expression of the Immature Neuron Marker Doublecortin Open
View article: Anti-Inflammatory Effect of Anti-TNF-α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model
Anti-Inflammatory Effect of Anti-TNF-α SiRNA Cationic Phosphorus Dendrimer Nanocomplexes Administered Intranasally in a Murine Acute Lung Injury Model Open
Inflammation is an essential component of many lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), or acute lung injury. Our purpose was to design efficient carriers for lung delivery of small interfering RNA (si…
View article: Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model
Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model Open
View article: Development and validation of a custom microarray for global transcriptome profiling of the fungus Aspergillus nidulans
Development and validation of a custom microarray for global transcriptome profiling of the fungus Aspergillus nidulans Open
View article: Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis
Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis Open
Hypoxia Inducible Factor (HIF) is the main transcription factor that mediates cell response to hypoxia. Howeverthe complex factor cascades induced by HIF during regenerative angiogenesis are currently incompletely mapped and the biological…