Claudio M. Fader
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View article: La confiance dans la radiothérapie mise à l’épreuve en raison de traumatismes de l’enfance
La confiance dans la radiothérapie mise à l’épreuve en raison de traumatismes de l’enfance Open
View article: A new role of RAB21 and VARP in autophagy and autophagic exocytosis of ATP
A new role of RAB21 and VARP in autophagy and autophagic exocytosis of ATP Open
Autophagy has been implicated in various cellular processes, including non-conventional secretion. Our previous findings suggest that ATP is loaded into amphisomes and secreted upon autophagy stimulation at focal adhesion sites in a VAMP7-…
View article: Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles
Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles Open
View article: Transmission Electron Microscopy to Follow Ultrastructural Modifications of Erythroblasts Upon ex vivo Human Erythropoiesis
Transmission Electron Microscopy to Follow Ultrastructural Modifications of Erythroblasts Upon ex vivo Human Erythropoiesis Open
Throughout mammal erythroid differentiation, erythroblasts undergo enucleation and organelle clearance becoming mature red blood cell. Organelles are cleared by autophagic pathways non-specifically targeting organelles and cytosolic conten…
View article: Editorial: New Roles of Autophagy Pathways in Cancer
Editorial: New Roles of Autophagy Pathways in Cancer Open
EDITORIAL article Front. Oncol., 07 July 2021Sec. Molecular and Cellular Oncology Volume 11 - 2021 | https://doi.org/10.3389/fonc.2021.726989
View article: Role of VAMP7-dependent secretion of reticulon 3 in neurite growth
Role of VAMP7-dependent secretion of reticulon 3 in neurite growth Open
(Cell Reports 33, 108536-1–108536-17.e1–e6; December 22, 2020) In the originally published version of this article, the Figure 4A panel and legend display incorrect p values. Additionally, in Figure 4A, light circles representing points ou…
View article: Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance
Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance Open
Erythroblast maturation in mammals is dependent on organelle clearance throughout terminal erythropoiesis. We studied the role of the outer mitochondrial membrane protein voltage-dependent anion channel-1 (VDAC1) in human terminal erythrop…
View article: Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth
Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth Open
View article: Effect of Autophagy Modulators on Vascular, Glial, and Neuronal Alterations in the Oxygen-Induced Retinopathy Mouse Model
Effect of Autophagy Modulators on Vascular, Glial, and Neuronal Alterations in the Oxygen-Induced Retinopathy Mouse Model Open
Hypoxia is one of the main insults in proliferative retinopathies, leading to neovascularization and neurodegeneration. To maintain homeostasis, neurons require efficient degradation and recycling systems. Autophagy participates in retinal…
View article: Hallmarks of Aging: An Autophagic Perspective
Hallmarks of Aging: An Autophagic Perspective Open
Autophagy is a major protein turnover pathway by which cellular components are delivered into the lysosomes for degradation and recycling. This intracellular process is able to maintain cellular homeostasis under stress conditions, and its…
View article: VAMP7-Dependent Autophagic Secretion Allows for Axonal Growth in Nutrient Restriction Conditions
VAMP7-Dependent Autophagic Secretion Allows for Axonal Growth in Nutrient Restriction Conditions Open
Hemin induces autophagy in a leukemic erythroblast cell line through the LRP1 receptor Open
View article: Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells
Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells Open
Low-density lipoprotein (LDL) receptor-related protein-1 (LRP1) is expressed in retinal Müller glial cells (MGCs) and regulates intracellular translocation to the plasma membrane (PM) of the membrane proteins involved in cellular motility …
View article: Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship
Diabetic nephropathy, autophagy and proximal tubule protein endocytic transport: A potentially harmful relationship Open
Diabetic nephropathy (DN) is the most frequent cause of chronic renal failure. Until now, the pathophysiological mechanisms that determine its development and progression have not yet been elucidated. In the present study, we evaluate the …
View article: Platelet rich plasma (PRP) induces autophagy in osteoblast precursor 3T3-L1
Platelet rich plasma (PRP) induces autophagy in osteoblast precursor 3T3-L1 Open
Autophagy is an essential cellular homeostatic mechanism by which intracellular components are delivered into the lysosomes for degradation and recycling. Autophagy has been related with a diversity of pathological or physi... | Find, read…
View article: Identification and characteristics of extracellular vesicles from bovine blastocysts produced in vitro
Identification and characteristics of extracellular vesicles from bovine blastocysts produced in vitro Open
Extracellular vesicles (EVs) have been identified within different body fluids and cell culture media. However, there is very little information on the secretion of these vesicles during early embryonic development. The aims of this work w…
View article: Hemin induces mitophagy in a leukemic erythroblast cell line
Hemin induces mitophagy in a leukemic erythroblast cell line Open
Background Information In eukaryotic cells, autophagy is considered a lysosomal catabolic process which participates in the degradation of intracellular components in a vacuolar structure termed autolysosome. This pathway plays a significa…
View article: Autophagy and proteins involved in vesicular trafficking
Autophagy and proteins involved in vesicular trafficking Open
Autophagy is an intracellular degradation system that, as a basic mechanism it delivers cytoplasmic components to the lysosomes in order to maintain adequate energy levels and cellular homeostasis. This complex cellular process is activate…