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View article: Association of hemispheric retinal oxygen extraction and macular plexus-specific capillary density in moderate to advanced glaucomatous hemifield defect
Association of hemispheric retinal oxygen extraction and macular plexus-specific capillary density in moderate to advanced glaucomatous hemifield defect Open
The aim was to characterize associations of the hemispheric retinal oxygen metabolism with glaucomatous damage and with retinal plexus-specific microvascular information in 35 hemispheres of 25 primary open-angle glaucoma patients with mod…
View article: Introduction and Validation of Low-Cost Ocular Biometry in Healthy and Cataractous Eyes Using a Thermally Tunable Swept-Source Laser
Introduction and Validation of Low-Cost Ocular Biometry in Healthy and Cataractous Eyes Using a Thermally Tunable Swept-Source Laser Open
Optical biometry using a thermally tunable VCSEL swept-source light source has the potential to provide clinically relevant biometric parameters at an unprecedented 100-fold lower price point than currently used state-of-the-art optical bi…
View article: Anatomical compensation of retinal nerve fiber layer improves the detection of glaucoma between ethnicities
Anatomical compensation of retinal nerve fiber layer improves the detection of glaucoma between ethnicities Open
The study aimed to evaluate the impact of compensating retinal nerve fiber layer (RNFL) thickness for demographic and anatomical factors on glaucoma detection in Chinese and Indian adults. A population‐based study included 1995 healthy par…
View article: Exploring single-mode VCSEL wavelength tuning for low-cost 3D optical coherence tomography and OCT angiography
Exploring single-mode VCSEL wavelength tuning for low-cost 3D optical coherence tomography and OCT angiography Open
Low-cost optical coherence tomography has recently emerged as a growing field due to the increased need for general availability of OCT devices outside of the clinics. One of the main obstacles in creating low-cost SS-OCT systems is the pr…
View article: Additional Guidance on the Use of the PRESERFLO™ MicroShunt in the Treatment of Glaucoma: Insights from a Second Delphi Consensus Panel
Additional Guidance on the Use of the PRESERFLO™ MicroShunt in the Treatment of Glaucoma: Insights from a Second Delphi Consensus Panel Open
INTRODUCTION: The PRESERFLO™ MicroShunt (PMS) has been proven to significantly lower intraocular pressure (IOP) in patients with glaucoma and has been available for use since 2019. With increasing published evidence and growing experience …
View article: PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract
PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract Open
Background: The purpose of this study was to evaluate the effectiveness and safety of the PreserFlo™ microshunt (PMS) using a 25-Gauge vs. 27-Gauge needle tract. Methods: This is a prospective postoperative examination of 60 glaucoma eyes …
View article: Characteristics of Henle’s fiber layer in healthy and glaucoma eyes assessed by polarization-sensitive optical coherence tomography
Characteristics of Henle’s fiber layer in healthy and glaucoma eyes assessed by polarization-sensitive optical coherence tomography Open
Using conventional optical coherence tomography (OCT), it is difficult to image Henle fibers (HF) due to their low backscattering potential. However, fibrous structures exhibit form birefringence, which can be exploited to visualize the pr…
View article: Assessing the external validity of machine learning-based detection of glaucoma
Assessing the external validity of machine learning-based detection of glaucoma Open
View article: Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view
Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view Open
We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization cau…
View article: Birefringent Properties of the Peripapillary Retinal Nerve Fiber Layer in Healthy and Glaucoma Subjects Analyzed by Polarization-Sensitive OCT
Birefringent Properties of the Peripapillary Retinal Nerve Fiber Layer in Healthy and Glaucoma Subjects Analyzed by Polarization-Sensitive OCT Open
We report a reduced BIR of the RNFL in early perimetric glaucoma, which can be interpreted as a sign of loss or change of intracellular microtubules and may contribute to a better understanding of early disease development. Prospective lon…
View article: Retinal Oxygen Extraction in Patients with Primary Open-Angle Glaucoma
Retinal Oxygen Extraction in Patients with Primary Open-Angle Glaucoma Open
Objective: To compare total retinal oxygen extraction between patients with primary open-angle glaucoma (POAG) and healthy control subjects. Design: A prospective, single-center, cross-sectional, case–control study performed at the Medical…
View article: Correction to: Expert Consensus on the Use of the PRESERFLO™ MicroShunt Device in the Treatment of Glaucoma: A Modified Delphi Panel
Correction to: Expert Consensus on the Use of the PRESERFLO™ MicroShunt Device in the Treatment of Glaucoma: A Modified Delphi Panel Open
View article: Expert Consensus on the Use of the PRESERFLO™ MicroShunt Device in the Treatment of Glaucoma: A Modified Delphi Panel
Expert Consensus on the Use of the PRESERFLO™ MicroShunt Device in the Treatment of Glaucoma: A Modified Delphi Panel Open
View article: A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease
A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease Open
View article: A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis
A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis Open
View article: Multivariate Normative Comparison, a Novel Method for Improved Use of Retinal Nerve Fiber Layer Thickness to Detect Early Glaucoma
Multivariate Normative Comparison, a Novel Method for Improved Use of Retinal Nerve Fiber Layer Thickness to Detect Early Glaucoma Open
View article: Temporal phase evolution OCT for measurement of tissue deformation in the human retina in-vivo
Temporal phase evolution OCT for measurement of tissue deformation in the human retina in-vivo Open
We demonstrate the use of temporal phase evolution (TPE-) OCT methods to evaluate retinal tissue deformation in-vivo over time periods of several seconds. A custom built spectral domain (SD)-OCT system with an integrated retinal tracker, e…
View article: Optical coherence tomography-measured retinal nerve fiber layer thickness values compensated with a multivariate model and discrimination between stable and progressing glaucoma suspects
Optical coherence tomography-measured retinal nerve fiber layer thickness values compensated with a multivariate model and discrimination between stable and progressing glaucoma suspects Open
View article: Needling and open filtering bleb revision after XEN-45 implantation—a retrospective outcome comparison
Needling and open filtering bleb revision after XEN-45 implantation—a retrospective outcome comparison Open
View article: Early Identification of Retinal Neuropathy in Subclinical Diabetic Eyes by Reduced Birefringence of the Peripapillary Retinal Nerve Fiber Layer
Early Identification of Retinal Neuropathy in Subclinical Diabetic Eyes by Reduced Birefringence of the Peripapillary Retinal Nerve Fiber Layer Open
We identified evidence of early neuroretinal alteration in diabetic eyes through reduced peripapillary RNFL birefringence assessed by PS-OCT occurring before appearance of clinical microvascular lesions or GCC alterations.
View article: Generating large field of view en-face projection images from intra-acquisition motion compensated volumetric optical coherence tomography data
Generating large field of view en-face projection images from intra-acquisition motion compensated volumetric optical coherence tomography data Open
A technique to generate large field of view projection maps of arbitrary optical coherence tomography (OCT) data is described. The technique is divided into two stages - an image acquisition stage that features a simple to use fast and rob…
View article: Analysis of retinal nerve fiber layer birefringence in patients with glaucoma and diabetic retinopathy by polarization sensitive OCT
Analysis of retinal nerve fiber layer birefringence in patients with glaucoma and diabetic retinopathy by polarization sensitive OCT Open
The retinal nerve fiber layer (RNFL) is a fibrous tissue that shows form birefringence. This optical tissue property is related to the microstructure of the nerve fiber axons that carry electrical signals from the retina to the brain. Ocul…
View article: Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1)
Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1) Open
View article: Structure-function relationship of circumpapillary polarisation sensitive optical coherence tomography scans and visual field maps in glaucoma
Structure-function relationship of circumpapillary polarisation sensitive optical coherence tomography scans and visual field maps in glaucoma Open
View article: Pyramid-based stitching approach of multiple PS-OCT volumes for wide field PS-OCT data
Pyramid-based stitching approach of multiple PS-OCT volumes for wide field PS-OCT data Open
View article: Diagnostic Ability of Individual Macular Layers by Spectral-Domain OCT in Different Stages of Glaucoma
Diagnostic Ability of Individual Macular Layers by Spectral-Domain OCT in Different Stages of Glaucoma Open
Single-layer mGCL thickness is comparable to the traditional cpRNFL thickness for the diagnosis of early/moderate glaucoma, whereas cpRNFL thickness remains the most efficient for advanced glaucoma. Combining macular measurements (GCL and …
View article: Analysis of longitudinal sections of retinal vessels using Doppler OCT
Analysis of longitudinal sections of retinal vessels using Doppler OCT Open
We present a new method for imaging retinal vessels that provides both structural and hemodynamic information. Our technique is based on a single beam OCT system with an integrated retinal tracker that enables recording of arbitrary scan p…
View article: Age-related changes of individual macular retinal layers among Asians
Age-related changes of individual macular retinal layers among Asians Open
View article: B-scan imaging along retinal vessels using OCT with tracking
B-scan imaging along retinal vessels using OCT with tracking Open
View article: Xen 45 surgical results: retrospective comparison of primary XEN implantation, filtering bleb needling and open filtering bleb revision
Xen 45 surgical results: retrospective comparison of primary XEN implantation, filtering bleb needling and open filtering bleb revision Open