Clément Kufe
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View article: Sex hormone-binding globulin, testosterone and type 2 diabetes risk in middle-aged African women: exploring the impact of HIV and menopause
Sex hormone-binding globulin, testosterone and type 2 diabetes risk in middle-aged African women: exploring the impact of HIV and menopause Open
Objectives Sex hormone-binding globulin (SHBG) and testosterone are differentially associated with type 2 diabetes (T2D) risk. We investigated whether these associations differ by HIV and menopausal status in Black South African women livi…
View article: SHBG, Free Testosterone, and Type 2 Diabetes Risk in Middle-aged African Men: A Longitudinal Study
SHBG, Free Testosterone, and Type 2 Diabetes Risk in Middle-aged African Men: A Longitudinal Study Open
Objectives To investigate longitudinal changes in SHBG and free testosterone (free T) levels among Black middle-aged African men, with and without coexistent HIV, and explore associations with incident dysglycaemia and measures of glucose …
View article: Reliability, validity and dimensionality of the 12-Item General Health Questionnaire among South African healthcare workers
Reliability, validity and dimensionality of the 12-Item General Health Questionnaire among South African healthcare workers Open
The study highlighted the gaps in the use of GHQ-12. The findings affirm the validity and reliability of the GHQ-12 in this group of professionals and the multidimensional structure for screening for psychological distress.
View article: Reliability, validity and dimensionality of the GHQ-12 in South African populations: Structural equation modelling (SEM)
Reliability, validity and dimensionality of the GHQ-12 in South African populations: Structural equation modelling (SEM) Open
Introduction Health Care Workers (HCWs) were among the high-risk groups for SARS-CoV-2 infection and suffer a high burden of poor mental health including depression, anxiety, traumatic stress, avoidance and burnout. The 12-Item General Hea…
View article: Targeted proteomics identifies potential biomarkers of dysglycaemia, beta cell function and insulin sensitivity in Black African men and women
Targeted proteomics identifies potential biomarkers of dysglycaemia, beta cell function and insulin sensitivity in Black African men and women Open
View article: Physical Behaviors and Their Association With Adiposity in Men and Women From a Low-Resourced African Setting
Physical Behaviors and Their Association With Adiposity in Men and Women From a Low-Resourced African Setting Open
Background : We first explored the associations between physical behaviors and total and regional adiposity. Second, we examined how reallocating time in different physical behaviors was associated with total body fat mass in men and women…
View article: Physical behaviors and their association with type 2 diabetes mellitus risk markers in urban South African middle-aged adults: an isotemporal substitutionapproach
Physical behaviors and their association with type 2 diabetes mellitus risk markers in urban South African middle-aged adults: an isotemporal substitutionapproach Open
Introduction To examine the associations between physical behaviors and type 2 diabetes mellitus (T2DM) risk markers in middle-aged South African men and women. Research design and methods This cross-sectional study included middle-aged me…
View article: Physical Activity Behaviors of a Middle-Age South African Cohort as Determined by Integrated Hip and Thigh Accelerometry
Physical Activity Behaviors of a Middle-Age South African Cohort as Determined by Integrated Hip and Thigh Accelerometry Open
Purpose Descriptive studies of objectively measured physical activity behaviors in African populations are rare. We developed a method of combining hip and thigh accelerometery signals to quantify and describe physical behaviors in middle-…
View article: Physical behaviours and their association with type 2 diabetes risk in urban South African middle-aged adults: An isotemporal substitution approach
Physical behaviours and their association with type 2 diabetes risk in urban South African middle-aged adults: An isotemporal substitution approach Open
Introduction To examine the associations between physical behaviours and type 2 diabetes mellitus (T2DM) risk in middle-aged South African men and women. Research design and methods This cross-sectional study included middle-aged men (n=40…
View article: Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women
Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women Open
Aims To determine the waist circumference (WC) thresholds for the prediction of incident dysglycaemia and type 2 diabetes (T2D) in Black South African (SA) men and women and to compare these to the advocated International Diabetes Federati…
View article: Author response for "Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women"
Author response for "Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women" Open
View article: Sex Differences in the Associations of Nutrient Patterns with Total and Regional Adiposity: A Study of Middle-Aged Black South African Men and Women
Sex Differences in the Associations of Nutrient Patterns with Total and Regional Adiposity: A Study of Middle-Aged Black South African Men and Women Open
The study evaluated the association between nutrient patterns with body fat and regional adiposity in middle-aged black South African (SA) men and women and determined if this differed by sex. Body fat and regional adiposity (dual-energy x…
View article: Author response for "Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women"
Author response for "Waist circumference thresholds predicting incident dysglycaemia and type 2 diabetes in Black African men and women" Open
View article: Increased Risk for Type 2 Diabetes in Relation to Adiposity in Middle-Aged Black South African Men compared to Women
Increased Risk for Type 2 Diabetes in Relation to Adiposity in Middle-Aged Black South African Men compared to Women Open
Aims Despite a higher prevalence of overweight/obesity in black South African women compared to men, the prevalence of type 2 diabetes does not differ. We explored if this could be due to sex differences in insulin sensitivity, clearance a…
View article: Physical activity and posture profile of a South African cohort of middle-aged men and women as determined by integrated hip and thigh accelerometry
Physical activity and posture profile of a South African cohort of middle-aged men and women as determined by integrated hip and thigh accelerometry Open
Background Physical activity and sedentary behaviour are central to public health recommendations and highlight the need for precise measurement. Descriptive studies of objectively measured physical activity behaviours in African populatio…
View article: Sex Differences in the Associations of Nutrient Patterns with Total and Regional Adiposity: A Study of Middle-Aged Black South African Men and Women
Sex Differences in the Associations of Nutrient Patterns with Total and Regional Adiposity: A Study of Middle-Aged Black South African Men and Women Open
The study evaluated the association between nutrient patterns and body fat and regional adiposity in middle-aged black South African (SA) men and women and determined if this differed by sex. Body fat and regional adiposity (dual-energy x-…
View article: Waist circumference thresholds predicting incident dysglycemia and type 2 diabetes in Black African men and women
Waist circumference thresholds predicting incident dysglycemia and type 2 diabetes in Black African men and women Open
Objective To determine the waist circumference (WC) thresholds for the prediction of incident dysglycemia and type 2 diabetes in Black South African (SA) men and women and compare these to advocated International Diabetes Federation (IDF) …
View article: Retention of health care workers at health facility, trends in the retention of knowledge and correlates at 3rd year following training of health care workers on the prevention of mother-to-child transmission (PMTCT) of HIV–National Assessment
Retention of health care workers at health facility, trends in the retention of knowledge and correlates at 3rd year following training of health care workers on the prevention of mother-to-child transmission (PMTCT) of HIV–National Assessment Open
Retention of trained HCWs at health facilities was high, mean scores for retention of knowledge was average and knowledge attrition was observed over time. This research is critical to understand where interventions may be most effective.
View article: Protocol for systematic review and meta-analysis of sex hormones and diabetes risk in ageing men and women of African ancestry
Protocol for systematic review and meta-analysis of sex hormones and diabetes risk in ageing men and women of African ancestry Open
Aim To present the protocol of a systematic review and meta-analysis of the available evidence examining the association between sex hormones and type 2 diabetes risk in ageing men and women of African descent. Methods We shall conduct a c…
View article: Risk factors of type 2 diabetes among Mbororo population of Guiwa-Yangamo village in the East-Cameroon
Risk factors of type 2 diabetes among Mbororo population of Guiwa-Yangamo village in the East-Cameroon Open
View article: Epidemiology of hypertension in Fulani indigenous populations—age, gender and drivers
Epidemiology of hypertension in Fulani indigenous populations—age, gender and drivers Open
View article: Distribution and patterning of non-communicable disease risk factors in indigenous Mbororo and non-autochthonous populations in Cameroon: cross sectional study
Distribution and patterning of non-communicable disease risk factors in indigenous Mbororo and non-autochthonous populations in Cameroon: cross sectional study Open
View article: Effects of Single and Multiple Blood Pressure Measurement Strategies on the Prediction of Prevalent Screen‐Detected Diabetes Mellitus: A Population‐Based Survey
Effects of Single and Multiple Blood Pressure Measurement Strategies on the Prediction of Prevalent Screen‐Detected Diabetes Mellitus: A Population‐Based Survey Open
The authors investigated the effects of single and multiple blood pressure ( BP ) measurements during the same encounter on screen‐detected diabetes risk. Data for 9018 Cameroonian adults from a community‐based survey were used. Resting BP…
View article: Risk factors of impaired fasting glucose and type 2 diabetes in Yaoundé, Cameroon: a cross sectional study
Risk factors of impaired fasting glucose and type 2 diabetes in Yaoundé, Cameroon: a cross sectional study Open
For successful primary prevention of T2D in the general population in Cameroon tailored efforts to address obesity, particularly abdominal obesity, and associated life-style factors are warranted.