Clément Rigaut
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View article: A new computational framework for simulating airway resistance, fraction of exhaled nitric oxide, and diffusing capacity for nitric oxide
A new computational framework for simulating airway resistance, fraction of exhaled nitric oxide, and diffusing capacity for nitric oxide Open
In this paper, we present a new computational framework for the simulation of airway resistance, the fraction of exhaled nitric oxide, and the diffusion capacity for nitric oxide in healthy and unhealthy lungs. Our approach is firstly base…
View article: A bouncing computational model of particle–mucus interaction for predictive deposition maps in the airways
A bouncing computational model of particle–mucus interaction for predictive deposition maps in the airways Open
In computational medicine, particle transport dynamics and deposition maps in the airways are of utmost importance in respiratory health. On the one hand, advantages include a better grasp of accurately delivering pharmaceutical drugs, enh…
View article: What Are the Key Anatomical Features for the Success of Nose-to-Brain Delivery? A Study of Powder Deposition in 3D-Printed Nasal Casts
What Are the Key Anatomical Features for the Success of Nose-to-Brain Delivery? A Study of Powder Deposition in 3D-Printed Nasal Casts Open
Nose-to-brain delivery is a promising way to improve the treatment of central nervous system disorders, as it allows the bypassing of the blood–brain barrier. However, it is still largely unknown how the anatomy of the nose can influence t…
View article: In vitro Evaluation of Paliperidone Palmitate Loaded Cubosomes Effective for Nasal-to-Brain Delivery
In vitro Evaluation of Paliperidone Palmitate Loaded Cubosomes Effective for Nasal-to-Brain Delivery Open
The chitosan coated cubosomal formulation seems to be the most promising formulation for nose-to-brain delivery. Indeed, it has a high mucoaffinity and a significantly higher apparent permeability coefficient than the two other formulation…
View article: Instillation of a Dry Powder in Nasal Casts: Parameters Influencing the Olfactory Deposition With Uni- and Bi-Directional Devices
Instillation of a Dry Powder in Nasal Casts: Parameters Influencing the Olfactory Deposition With Uni- and Bi-Directional Devices Open
Nose-to-brain delivery is a promising way to reach the central nervous system with therapeutic drugs. However, the location of the olfactory region at the top of the nasal cavity complexifies this route of administration. In this study, we…
View article: Comprehensive Analysis of Heat and Water Exchanges in the Human Lungs
Comprehensive Analysis of Heat and Water Exchanges in the Human Lungs Open
This work presents a new mathematical model of the heat and water exchanges in the human lungs (newborn to adult). This model is based on a local description of the water and energy transports in both the lumen and the surrounding tissues,…
View article: Refraction law and Fermat principle: a project using the ant colony optimization algorithm for undergraduate students in physics
Refraction law and Fermat principle: a project using the ant colony optimization algorithm for undergraduate students in physics Open
info:eu-repo/semantics/published