Clive R. Wood
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View article: Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations
Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations Open
Advancements in long-read sequencing technology have accelerated the study of large structural variants (SVs). We created a curated, publicly available, multi-ancestry SV imputation panel by long-read sequencing 888 samples from the 1000 G…
View article: Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations
Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations Open
Advancements in long-read sequencing technology have accelerated the study of large structural variants (SVs). We created a curated, publicly available, multi-ancestry SV imputation panel by long-read sequencing 888 samples from the 1000 G…
View article: Role of Exogenous HSPB1 in Cytokine Regulation Through TLR2, TLR4, TLR5, TLR7, and MyD88/MAPK p38/NF-κB Pathways in Differentiated THP-1 Cells
Role of Exogenous HSPB1 in Cytokine Regulation Through TLR2, TLR4, TLR5, TLR7, and MyD88/MAPK p38/NF-κB Pathways in Differentiated THP-1 Cells Open
The modulation of the innate immune system has been a significant area of interest in research, as it represents the body’s first line of defense against pathogens. Heat shock proteins (HSPs), particularly small HSP, like HSPB1 (HSP27), ar…
View article: Role of Exogenous HSPA1A in Cytokine Regulation Through TLR2, TLR4, TLR5, TLR7, and MyD88/MAPK p38/NF-κB Pathways in Differentiated THP-1 Cells
Role of Exogenous HSPA1A in Cytokine Regulation Through TLR2, TLR4, TLR5, TLR7, and MyD88/MAPK p38/NF-κB Pathways in Differentiated THP-1 Cells Open
Heat shock proteins (HSPs) are ubiquitous proteins that play an important role in cellular stress responses, contributing to immune activation through interactions with toll-like receptors (TLRs) and other pattern recognition receptors. De…
View article: Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations
Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations Open
Advancements in long-read sequencing technology have accelerated the study of large structural variants (SVs). We created a curated, publicly available, multi-ancestry SV imputation panel by long-read sequencing 888 samples from the 1000 G…
View article: Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
View article: Data from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Data from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Inhibition of specific matrix metalloproteinases (MMP) is an attractive noncytotoxic approach to cancer therapy. MMP-14, a membrane-bound zinc endopeptidase, has been proposed to play a central role in tumor growth, invasion, and neovascul…
View article: Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
View article: Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
View article: Data from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Data from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Inhibition of specific matrix metalloproteinases (MMP) is an attractive noncytotoxic approach to cancer therapy. MMP-14, a membrane-bound zinc endopeptidase, has been proposed to play a central role in tumor growth, invasion, and neovascul…
View article: Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis Open
Supplementary Tables1-2 from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
View article: opnMe.com: a digital initiative for sharing tools with the biomedical research community
opnMe.com: a digital initiative for sharing tools with the biomedical research community Open
View article: Fully Human Monoclonal Antibody Inhibitors of the Neonatal Fc Receptor Reduce Circulating IgG in Non-Human Primates
Fully Human Monoclonal Antibody Inhibitors of the Neonatal Fc Receptor Reduce Circulating IgG in Non-Human Primates Open
The therapeutic management of antibody-mediated autoimmune disease typically involves immunosuppressant and immunomodulatory strategies. However, perturbing the fundamental role of the neonatal Fc receptor (FcRn) in salvaging IgG from lyso…