Cole Cassady
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View article: Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection
Design and nonviral delivery of live attenuated vaccine to prevent chronic hepatitis C virus-like infection Open
View article: Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection
Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection Open
Immune correlates of hepatitis C virus (HCV) clearance and control remain poorly defined due to the lack of an informative animal model. We recently described acute and chronic rodent HCV-like virus (RHV) infections in lab mice. Here, we d…
View article: SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern
SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern Open
The spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the main target for neutralizing antibodies (NAbs). The S protein trimer is anchored in the virion membrane in its prefusion (preS) but metastable for…