Explanipedia

WCN25-1253 SMALL MOLECULE DRUG TREATMENTS FOR INHERITED KIDNEY DISEASE: NEPHRONOPHTHISIS Open

Praveen Dhondurao Sudhindar, Elisa Molinari, Colin G. Johnson, Colin G. Miles, John A. Sayer · 2025

Microscale velocity-dependent unbinding generates a macroscale performance-efficiency tradeoff in actomyosin systems Open

Jake McGrath, Brian R. Kent, Colin G. Johnson, José Alvarado · 2024

Myosin motors are fundamental biological actuators, powering diverse mechanical tasks in eukaryotic cells via ATP hydrolysis. Recent work revealed that myosin's velocity-dependent detachment rate can bridge actomyosin dynamics to macroscal…

Adapting genetic algorithms for multifunctional landscape decisions: A theoretical case study on wild bees and farmers in the <span>UK</span> Open

Ellen Knight, Heiko Balzter, Tom D. Breeze, Julia Brettschneider, Robbie D. Girling , et al. · 2024

Spatial modelling approaches to aid land‐use decisions which benefit both wildlife and humans are often limited to the comparison of pre‐determined landscape scenarios, which may not reflect the true optimum landscape for any end‐user. Fur…

New directions in fitness evaluation: commentary on Langdon’s JAWS30 Open

Colin G. Johnson · 2023

Langdon's paper emphasises the key role of fitness in GP, yet notes issues with current approaches to fitness: "In GP, as in most optimisation problems, most of the computation effort is spent on evaluating how good the proposed solutions …

Middle Palaeolithic occupation of the southern North Sea Basin: evidence from the Sandscaping sediments emplaced on the beach between Bacton and Walcott, Norfolk, UK Open

R. J. Davis, Nick Ashton, Rachel Bynoe, J. D. Craven, Rob Ferguson , et al. · 2023

During the summer of 2019, the Bacton to Walcott Coastal Management Scheme involved the emplacement on to the foreshore of 1.8 million cubic metres of sand and gravel dredged from the submerged sediments of the Palaeo‐Yare in the southern …

Metaheuristics “In the Large” Open

Jerry Swan, Steven Adriænsen, Alexander E. I. Brownlee, Kevin Hammond, Colin G. Johnson , et al. · 2021

Development of a Mechatronic System for Plant Recognition and Intra-row Weeding With Machine Vision Open

Nicole Berkmortel, Matthew Curtis, Colin G. Johnson, Alicia Schmidt, Elyse Hill , et al. · 2021

In this paper, an electro-mechanical integrated weed management system was designed, constructed, and tested. This laboratory-scale solution integrated elements of machine vision, controls, and mechanical actuation to selectively remove we…

Solving the Rubik's cube with stepwise deep learning Open

Colin G. Johnson · 2021

This paper explores a novel technique for learning the fitness function for search algorithms such as evolutionary strategies and hillclimbing. The aim of the new technique is to learn a fitness function (called a Learned Guidance Function…

Creating a Digital Mirror of Creative Practice Open

Colin G. Johnson · 2021

Gender effects on quality of life and symptom burden in patients with lung cancer: results from a prospective, cross-cultural, multi-center study Open

Myriam Koch, Marianne Jensen Hjermstad, Krzysztof A. Tomaszewski, Iwona M. Tomaszewska, Kjersti Hornslien , et al. · 2020

This study adds to the literature in showing that the typical QoL gender difference effect (women doing worse than men) may not be generalizable across all patient samples.

Creative autonomy in a simple interactive music system Open

Fabio Paolizzo, Colin G. Johnson · 2020

Can autonomous systems be musically creative without musical knowledge? Assumptions from interdisciplinary studies on self-reflection are evaluated using Video Interactive VST Orchestra, a system that generates music from audio and video i…

Software Fault Localisation via Probabilistic Modelling Open

Colin G. Johnson · 2020

GI 2019 Program Committee Open

Brad Alexander, Nadia Facebook, Anikó Ekárt, Saemundur Haraldson, Ciera Jaspan , et al. · 2019

Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity Open

Christopher J. Bott, Colin G. Johnson, Chan Choo Yap, Noelle D. Dwyer, Karen Litwa , et al. · 2019

Correct wiring in the neocortex requires that responses to an individual guidance cue vary among neurons in the same location, and within the same neuron over time. Nestin is an atypical intermediate filament expressed strongly in neural p…

Tensión en la superficie: Improvisando el Performance de la Materialidad Tecnológica en la Obra Glitchbody/Nanostalgia [1454-2015] Open

Colin G. Johnson · 2019

En la primavera de 2015, UC (Universidad de California) Davis invitó al artista del performance Guillermo Gomez-Peña a colaborar en una pieza llamada Glitchbody / Nanostalgia [1454-2015]. Glitch intentó involucrar tecnologías de vigilancia…

Understanding Aesthetics and Fitness Measures in Evolutionary Art Systems Open

Colin G. Johnson, Jon McCormack, Iria Santos, Juan Romero · 2019

One of the general aims of evolutionary art research is to build a computer system capable of creating interesting, beautiful, or creative results, including images, videos, animations, text, and performances. In this context, it is crucia…

Complex Systems in Aesthetics and Arts Open

Juan Romero, Colin G. Johnson, Jon McCormack · 2019

Editorial for a special issue of the journal Complexity on complex systems in aesthetics and the arts.

The EORTC CAT Core—The computer adaptive version of the EORTC QLQ-C30 questionnaire Open

Morten Aagaard Petersen, Neil K. Aaronson, Juan Ignacio Arrarás, Wei‐Chu Chie, Thierry Conroy , et al. · 2018

Nestin in immature embryonic neurons regulates axon growth cone morphology and Semaphorin3a sensitivity Open

Christopher J. Bott, Colin G. Johnson, Chan Choo Yap, Noelle D. Dwyer, Karen Litwa , et al. · 2017

Correct wiring in the neocortex requires that responses to an individual guidance cue vary among neurons in the same location, and within the same neuron over time. Nestin is an atypical intermediate filament expressed highly in neural pro…

Creative Autonomy Through Salience and Multidominance in Interactive Music Systems: Evaluating an Implementation Open

Fabio Paolizzo, Colin G. Johnson · 2017

Interactive music systems always exhibit some autonomy in the creative process. The capacity to generate novel material while retaining mutuality to the interaction is proposed here as the bare minimum for creative autonomy in such systems…

Creative Autonomy Through Salience and Multidominance in Interactive\n Music Systems: Evaluating an Implementation Open

Fabio Paolizzo, Colin G. Johnson · 2017

Interactive music systems always exhibit some autonomy in the creative\nprocess. The capacity to generate novel material while retaining mutuality to\nthe interaction is proposed here as the bare minimum for creative autonomy in\nsuch syst…

Autonomy in the interactive music system VIVO. Open

Fabio Paolizzo, Colin G. Johnson · 2017

Interactive Music Systems (IMS) have introduced a new world of music-making modalities. But can we really say that they create music, as in true autonomous creation? Here we discuss Video Interactive VST Orchestra (VIVO), an IMS that consi…

The Year in Computing Initiative Open

Sebastian Dziallas, Sally Fincher, Colin G. Johnson, Ian Utting · 2017

Pro‐migratory and TGF‐β‐activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8‐dependent GTPase switch Open

Jo Tod, Christopher J. Hanley, Mark R. Morgan, Marta Rucka, Toby Mellows , et al. · 2017

The integrin αvβ6 is up‐regulated in numerous carcinomas, where expression commonly correlates with poor prognosis. αvβ6 promotes tumour invasion, partly through regulation of proteases and cell migration, and is also the principal mechani…

A Situation-Aware Fear Learning (SAFEL) model for robots Open

Caroline Rizzi, Colin G. Johnson, Fábio Fabris, Patrícia A. Vargas · 2016

This work proposes a novel Situation-Aware FEar Learning (SAFEL) model for robots. SAFEL combines concepts of situation-aware expert systems with well-known neuroscientific findings on the brain fear-learning mechanism to allow companion r…

Evals is Not Enough Open

John R. Woodward, Alexander E. I. Brownlee, Colin G. Johnson · 2016

Have you ever noticed that your car never achieves the fuel economy claimed by the manufacturer? Does this seem unfair? Unscientific? Would you like the same situation to occur in Genetic Improvement? Comparison will always be difficult [9…

Fitness in evolutionary art and music: a taxonomy and future prospects Open

Colin G. Johnson · 2016

This paper is concerned with the idea of fitness in art and music systems that are based on evolutionary computation. A taxonomy is presented of the ways in which fitness is used in such systems, with two dimensions: what the fitness funct…

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