Colin Olito
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View article: Effects of inbreeding on balancing selection: insights from Fisher's geometric model
Effects of inbreeding on balancing selection: insights from Fisher's geometric model Open
Balancing selection is a potentially important factor in the maintenance of genetic variation for fitness and, alongside recessive deleterious mutations, the genetic basis of inbreeding depression. Classic population genetics theory predic…
View article: The evolution of suppressed recombination between sex chromosomes and the lengths of evolutionary strata
The evolution of suppressed recombination between sex chromosomes and the lengths of evolutionary strata Open
The idea that sex-differences in selection drive the evolution of suppressed recombination between sex chromosomes is well-developed in population genetics. Yet, despite a now classic body of theory, empirical evidence that sexually antago…
View article: Predicting the prevalence of genetic trade-offs among adaptive substitutions
Predicting the prevalence of genetic trade-offs among adaptive substitutions Open
Genetic trade-offs—which occur when variants that are beneficial in some contexts of natural selection are harmful in others—can influence a wide range of evolutionary phenomena, from the maintenance of genetic variation to the evolution o…
View article: A century of theories of balancing selection
A century of theories of balancing selection Open
Traits that affect organismal fitness are often very genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature (after all) “selects” the best genotypes…
View article: Making sense of recent models of the “sheltering” hypothesis for recombination arrest between sex chromosomes
Making sense of recent models of the “sheltering” hypothesis for recombination arrest between sex chromosomes Open
In their most extreme form, sex chromosomes exhibit a complete lack of genetic recombination along much of their length in the heterogametic sex. Some recent models explain the evolution of such suppressed recombination by the “sheltering”…
View article: Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes
Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes Open
The evolution of suppressed recombination between sex chromosomes is widely hypothesized to be driven by sexually antagonistic selection (SA), where tighter linkage between the sex-determining gene(s) and nearby SA loci is favored when it …
View article: Do deleterious mutations promote the evolution of recombination suppression between X and Y chromosomes?
Do deleterious mutations promote the evolution of recombination suppression between X and Y chromosomes? Open
An interesting new model has recently been proposed for the evolution of suppressed recombination between newly evolving X and Y chromosomes, where males are heterozygous for a locus determining sex and females are homozygous (the same pri…
View article: The evolutionary maintenance of ancient recombining sex chromosomes in the ostrich
The evolutionary maintenance of ancient recombining sex chromosomes in the ostrich Open
Sex chromosomes have evolved repeatedly across the tree of life and often exhibit extreme size dimorphism due to genetic degeneration of the sex-limited chromosome (e.g. the W chromosome of some birds and Y chromosome of mammals). However,…
View article: Why is measuring and predicting fitness under genomic conflict so hard?
Why is measuring and predicting fitness under genomic conflict so hard? Open
Genomic conflict between the sexes is caused by differences in the optimal male and female reproductive strategies, and is a major contributor to genetic, phenotypic, and life history variation. While early experimental work appeared to st…
View article: RETRACTED AND REPLACED: The evolution of suppressed recombination between sex chromosomes and the lengths of evolutionary strata
RETRACTED AND REPLACED: The evolution of suppressed recombination between sex chromosomes and the lengths of evolutionary strata Open
The idea that sex differences in selection drive the evolution of suppressed recombination between sex chromosomes is well developed in population genetics. Yet, despite a now classic body of theory, empirical evidence that sexually antago…
View article: Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes
Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes Open
The evolution of suppressed recombination between sex chromosomes is widely hypothesized to be driven by sexually antagonistic selection (SA), where tighter linkage between the sex-determining gene(s) and nearby SA loci is favored when it …
View article: The Demographic Costs of Sexually Antagonistic Selection in Partially Selfing Populations
The Demographic Costs of Sexually Antagonistic Selection in Partially Selfing Populations Open
When selection differs between the sexes, genes expressed by both males and females can experience sexually antagonistic (SA) selection, where beneficial alleles for one sex are deleterious for the other. Classic population genetics theory…
View article: The demographic costs of sexually antagonistic selection in partially selfing populations
The demographic costs of sexually antagonistic selection in partially selfing populations Open
Classic population genetics theory has been fundamental to understanding the evolution of sex-differences and the maintenance of sexually antagonistic (SA) genetic variation, but these models have rarely considered the demographic conseque…
View article: Sexually antagonistic coevolution between the sex chromosomes of <i>Drosophila melanogaster</i>
Sexually antagonistic coevolution between the sex chromosomes of <i>Drosophila melanogaster</i> Open
Significance Sex chromosomes are not only involved in genetic sex determination—they are also important factors in sexual conflict and speciation. Using laboratory experiments and population genetic modeling, we show that the sex chromosom…
View article: The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics
The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics Open
Sexually antagonistic (SA) genetic variation—in which alleles favored in one sex are disfavored in the other—is predicted to be common and has been documented in several animal and plant populations, yet we currently know little about its …
View article: The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics
The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics Open
Sexually antagonistic (SA) genetic variation—in which genotypes favoured in one sex are disfavoured in the other—is predicted to be common and has been documented in several animal and plant populations, yet we currently know little about …
View article: The evolution of suppressed recombination between sex chromosomes by chromosomal inversions
The evolution of suppressed recombination between sex chromosomes by chromosomal inversions Open
The idea that sex-differences in selection drive the evolution of suppressed recombination between sex chromosomes is well-developed in population genetics. Yet, despite a now classic body of theory, empirical evidence that sexual antagoni…
View article: Sexually antagonistic coevolution between the sex chromosomes of <i>Drosophila melanogaster</i>
Sexually antagonistic coevolution between the sex chromosomes of <i>Drosophila melanogaster</i> Open
Antagonistic interactions between the sexes are important drivers of evolutionary divergence. Interlocus sexual conflict is generally described as a conflict between alleles at two interacting loci whose identity and genomic location are a…
View article: Releasing small ejaculates slowly increases per-gamete fertilization success in an external fertilizer: <i>Galeolaria caespitosa</i> (Polychaeta: Serpulidae)
Releasing small ejaculates slowly increases per-gamete fertilization success in an external fertilizer: <i>Galeolaria caespitosa</i> (Polychaeta: Serpulidae) Open
The idea that male reproductive strategies evolve primarily in response to sperm competition is almost axiomatic in evolutionary biology. However, externally fertilizing species, especially broadcast spawners, represent a large and taxonom…
View article: Local adaptation and the evolution of inversions on sex chromosomes and autosomes
Local adaptation and the evolution of inversions on sex chromosomes and autosomes Open
Spatially varying selection with gene flow can favour the evolution of inversions that bind locally adapted alleles together, facilitate local adaptation and ultimately drive genomic divergence between species. Several studies have shown t…
View article: The interaction between sex-specific selection and local adaptation in species without separate sexes
The interaction between sex-specific selection and local adaptation in species without separate sexes Open
Local adaptation in hermaphrodite species can be based on a variety of fitness components, including survival, as well as both female and male sex-functions within individuals. When selection via female and male fitness components varies s…
View article: Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes.
Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes. Open
Higher resolution versions of the figures in Appendix A
View article: Appendix B - Model Analytic Results PDF from The interaction between sex-specific selection and local adaptation in species without separate sexes
Appendix B - Model Analytic Results PDF from The interaction between sex-specific selection and local adaptation in species without separate sexes Open
A PDF file of Appendix B
View article: Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes
Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes Open
Mathematica code to reproduce key analytical results
View article: Supplementary material from "Local adaptation and the evolution of inversions on sex chromosomes and autosomes"
Supplementary material from "Local adaptation and the evolution of inversions on sex chromosomes and autosomes" Open
Spatially varying selection with gene flow can favour the evolution of inversions that bind locally adapted alleles together, facilitate local adaptation and ultimately drive genomic divergence between species. Several studies have shown t…
View article: Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes.
Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes. Open
Mathematica code to reproduce key analytical results
View article: Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes
Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes Open
Higher resolution versions of the figures in Appendix A
View article: Supplementary material from "The interaction between sex-specific selection and local adaptation in species without separate sexes"
Supplementary material from "The interaction between sex-specific selection and local adaptation in species without separate sexes" Open
Local adaptation in hermaphrodite species can be based on a variety of fitness components, including survival, as well as both female and male sex-functions within individuals. When selection via female and male fitness components varies s…
View article: Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes
Supplementary figures from The interaction between sex-specific selection and local adaptation in species without separate sexes Open
Higher resolution versions of the figures in Appendix A
View article: Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes
Appendix B - Model Analytic Results from The interaction between sex-specific selection and local adaptation in species without separate sexes Open
Mathematica code to reproduce key analytical results