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View article: Clinical and Genetic Characterization of the Largest Cohort of Patients With <scp>D3</scp> Limb‐Girdle Muscular Dystrophy in an Isolated Uruguayan Population
Clinical and Genetic Characterization of the Largest Cohort of Patients With <span>D3</span> Limb‐Girdle Muscular Dystrophy in an Isolated Uruguayan Population Open
Background Limb‐girdle muscular dystrophies (LGMD) are a heterogeneous group of genetic disorders characterized by progressive proximal weakness. LGMD D3 is an extremely rare autosomal dominant myopathy caused by pathogenic variants in the…
View article: Mortality burden and economic loss attributable to cold and heat in Central and South America
Mortality burden and economic loss attributable to cold and heat in Central and South America Open
Background: We quantify the mortality burden and economic loss attributable to nonoptimal temperatures for cold and heat in the Central and South American countries in the Multi-City Multi-Country (MCC) Collaborative Research Network. Meth…
View article: Regional variation in the role of humidity on city-level heat-related mortality
Regional variation in the role of humidity on city-level heat-related mortality Open
The rising humid heat is regarded as a severe threat to human survivability, but the proper integration of humid heat into heat-health alerts is still being explored. Using state-of-the-art epidemiological and climatological datasets, we e…
View article: All-cause, cardiovascular, and respiratory mortality and wildfire-related ozone: a multicountry two-stage time series analysis
All-cause, cardiovascular, and respiratory mortality and wildfire-related ozone: a multicountry two-stage time series analysis Open
Australian Research Council and the Australian National Health and Medical Research Council.
View article: Health and Economic Benefits of Complying With the World Health Organization Air Quality Guidelines for Particulate Matter in Nine Major Latin American Cities
Health and Economic Benefits of Complying With the World Health Organization Air Quality Guidelines for Particulate Matter in Nine Major Latin American Cities Open
Objectives This study aims to estimate the short-term preventable mortality and associated economic costs of complying with the World Health Organization (WHO) air quality guidelines (AQGs) limit values for PM 10 and PM 2.5 in nine major L…
View article: Extreme Temperatures and Stroke Mortality: Evidence From a Multi-Country Analysis
Extreme Temperatures and Stroke Mortality: Evidence From a Multi-Country Analysis Open
BACKGROUND: Extreme temperatures contribute significantly to global mortality. While previous studies on temperature and stroke-specific outcomes presented conflicting results, these studies were predominantly limited to single-city or sin…
View article: Impact of population aging on future temperature-related mortality at different global warming levels
Impact of population aging on future temperature-related mortality at different global warming levels Open
Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we sho…
View article: Noise Dosimetries during Active Transport in Montevideo, Uruguay: Evaluation of Potential Influencing Factors from Experimental Data
Noise Dosimetries during Active Transport in Montevideo, Uruguay: Evaluation of Potential Influencing Factors from Experimental Data Open
This article presents a case study related to environmental noise exposure of cyclists in Montevideo (Uruguay), as a part of a wider interdisciplinary research project. The main objective of this study was to find the most important parame…
View article: Associations between Environmental Exposure, Urban Environment Parameters and Meteorological Conditions, during Active Travel in Montevideo, Uruguay
Associations between Environmental Exposure, Urban Environment Parameters and Meteorological Conditions, during Active Travel in Montevideo, Uruguay Open
Introduction: Active transport is encouraged by the Uruguayan authorities; however, the criteria for expanding the cycling routes are unclear. This article presents a research project aiming to examine statistically significant links betwe…
View article: Colorectal cancer. Genetic variants in BMP signaling pathway and ancestry in the Mexican population
Colorectal cancer. Genetic variants in BMP signaling pathway and ancestry in the Mexican population Open
The study replicated the associations between colorectal cancer and SMAD7 and BMP4 variants, with an association being observed with the Caucasian component of the ethnic mix.
View article: Periodontitis prevalence and associated factors: a comparison of two examination protocols
Periodontitis prevalence and associated factors: a comparison of two examination protocols Open
The fact that there are different epidemiological definitions of periodontitis and different evaluation protocols affects the estimate of periodontitis prevalence and of the influence of associated factors. The gold standard for periodonta…
View article: Associations Between Extreme Temperatures and Cardiovascular Cause-Specific Mortality: Results From 27 Countries
Associations Between Extreme Temperatures and Cardiovascular Cause-Specific Mortality: Results From 27 Countries Open
Background: Cardiovascular disease is the leading cause of death worldwide. Existing studies on the association between temperatures and cardiovascular deaths have been limited in geographic zones and have generally considered associations…
View article: Predicting severe maternal outcomes in a network of sentinel sites in Latin‐American countries
Predicting severe maternal outcomes in a network of sentinel sites in Latin‐American countries Open
Objective This study aimed to determine incidences of potentially life‐threatening conditions (PLTC), maternal near misses (MNM), and maternal deaths (MD) in women who gave birth in participating facilities, and to determine the probabilit…
View article: Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study
Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study Open
Background The use of caesarean section has steadily increased, with Latin America being the region with the highest rates. Multiple factors account for that increase and the Robson classification is appropriate to compare determinants at …
View article: Comparison of weather station and climate reanalysis data for modelling temperature-related mortality
Comparison of weather station and climate reanalysis data for modelling temperature-related mortality Open
Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an altern…
View article: Fluctuating temperature modifies heat-mortality association around the globe
Fluctuating temperature modifies heat-mortality association around the globe Open
Studies have investigated the effects of heat and temperature variability (TV) on mortality. However, few assessed whether TV modifies the heat-mortality association. Data on daily temperature and mortality in the warm season were collecte…
View article: Additional file 2 of Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study
Additional file 2 of Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study Open
Additional file 2.
View article: Additional file 1 of Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study
Additional file 1 of Cesarean section in Uruguay from 2008 to 2018: country analysis based on the Robson classification. An observational study Open
Additional file 1.
View article: Dyslipidemia, Obesity, and Ethnicity in Mexican Children
Dyslipidemia, Obesity, and Ethnicity in Mexican Children Open
The aim of this study was to assess lipid disorders in children from five ethnic groups, both urban and indigenous, from northern and central Mexico. We measured the lipid profile to determine the ability of the body mass index (BMI) to di…