Colleen Carpenter
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View article: Phenotypic analysis of catastrophic childhood epilepsy genes: The Epilepsy Zebrafish Project
Phenotypic analysis of catastrophic childhood epilepsy genes: The Epilepsy Zebrafish Project Open
Genetic engineering techniques have contributed to the now widespread use of zebrafish to investigate gene function, but zebrafish-based human disease studies, and particularly for neurological disorders, are limited. Here we used CRISPR-C…
View article: Ruboxistaurin Reduces Cocaine-Stimulated Increases in Extracellular Dopamine by Modifying Dopamine-Autoreceptor Activity
Ruboxistaurin Reduces Cocaine-Stimulated Increases in Extracellular Dopamine by Modifying Dopamine-Autoreceptor Activity Open
Cocaine is a highly abused drug, and cocaine addiction affects millions of individuals worldwide. Cocaine blocks normal uptake function at the dopamine transporter (DAT), thus increasing extracellular dopamine. Currently, no chemical thera…
View article: Revisiting the Tamoxifen Scaffold to Create Therapeutics to Treat\nAmphetamine Abuse
Revisiting the Tamoxifen Scaffold to Create Therapeutics to Treat\nAmphetamine Abuse Open
Amphetamine (AMPH) and its congeners are the second most widely abused drugs globally and their continued overuse comes with a high economic, health and social cost. Yet after decades of research, an effective treatment for AMPH abuse and …
View article: Revisiting the Tamoxifen Scaffold to Create Therapeutics to TreatAmphetamine Abuse
Revisiting the Tamoxifen Scaffold to Create Therapeutics to TreatAmphetamine Abuse Open
Amphetamine (AMPH) and its congeners are the second most widely abused drugs globally and their continued overuse comes with a high economic, health and social cost. Yet after decades of research, an effective treatment for AMPH abuse and …