Explanipedia

280P Machine learning for multi-omics risk prediction of cholangiocarcinoma in the general population Open

Felix van Haag, Jan Clusmann, Tobias Seibel, Niharika Jakhar, Dongming Zhang , et al. · 2025

Metabolomics using high-resolution magic angle spinning nuclear magnetic resonance: Neurotoxicological applications Open

Rachel Neita, Kenna Hynes, Grace V. Mercer, C. Schneider, Lindsay S. Cahill · 2025

High-resolution magic angle spinning nuclear magnetic resonance (HRMAS NMR) is a cutting-edge technology for metabolomics studies that has found application in pharmacology and toxicology. Metabolomics provides insight into how biological …

A mixed methods exploration of self-presentation, authenticity, and role model function on Instagram: perspectives from female influencers in Germany Open

Daniel Zimmermann, C. Schneider, Kai Kaspar · 2025

Introduction Social media influencers focussing on beauty, fashion, and fitness topics (BFFI) are important opinion leaders on Instagram. Nevertheless, they are criticized for their potential negative influence on their followers' physical…

<sup>19</sup>F solid-state nuclear magnetic resonance as a tool to study the bioaccumulation of per- and polyfluoroalkyl substances in murine tissue samples Open

Rachel Neita, Sophie Kiefte, Haley Adams, Lindsay S. Cahill, Grace V. Mercer , et al. · 2025

Using solid-state MAS NMR, PFOA was detected in murine liver, adipose tissue and the placenta.

MDB-26. GENE REGULATORY NETWORK LANDSCAPE OF GROUP 3/4 MEDULLOBLASTOMA Open

Piyush Joshi, Tamina Stelzer, Konstantin Okonechnikov, Ioannis Sarropoulos, Mari Sepp , et al. · 2024

Intra-tumor heterogeneity in brain cancers contributes to therapy resistance and relapse through positive selection of resistant tumor cell populations. Resolving the molecular mechanisms driving intra-tumor heterogeneity will uncover tumo…

Differential impact of perfluorooctanoic acid and fluorotelomer ethoxylates on placental metabolism in mice Open

Haley Adams, Jenna Hanrahan, Sophie Kiefte, Thomas O’Brien, Grace V. Mercer , et al. · 2024

Poly- and perfluoroalkyl substances (PFAS) are a group of compounds with uses in industry and many consumer products. Concerns about the potential health effects of these compounds resulted in regulation by the Stockholm Convention on the …

Gene regulatory network landscape of Group 3/4 medulloblastoma Open

Piyush Joshi, Tamina Stelzer, Konstantin Okonechnikov, Ioannis Sarropoulos, Mari Sepp , et al. · 2024

Resolving the molecular mechanisms driving childhood brain tumors will uncover tumor-specific vulnerabilities and advance mechanism-of-action-based therapies. Here we describe a continuum of cell-states in Group 3/4 medulloblastomas, the m…

Cellular development and evolution of the mammalian cerebellum Open

Mari Sepp, Kevin Leiss, Florent Murat, Konstantin Okonechnikov, Piyush Joshi , et al. · 2023

The expansion of the neocortex, a hallmark of mammalian evolution 1,2 , was accompanied by an increase in cerebellar neuron numbers 3 . However, little is known about the evolution of the cellular programmes underlying the development of t…

A structure function analysis of naturally-occurring variants in angiopoietin like 3 (ANGPTL3) to identify regions involved in the inhibition of LPL and EL function Open

Cecilia Vitali, C. Schneider, Daniel J. Rader, Marina Cuchel · 2023

Cellular development and evolution of the mammalian cerebellum Open

Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, Konstantin Okonechnikov , et al. · 2021

The expansion of the neocortex, one of the hallmarks of mammalian evolution 1,2 , was accompanied by an increase in the number of cerebellar neurons 3 . However, little is known about the evolution of the cellular programs underlying cereb…

Demystifying and Unravelling the Factual Molecular Structure of the Biopolymer Sporopollenin Open

Abanoub Mikhael, Kristina Jurčić, C. Schneider, David carr, Gregory L. Fisher , et al. · 2019

Sporopollenin is a natural, highly cross-linked biopolymer composed of carbon, hydrogen, and oxygen, which forms the outer wall of pollen grains. Sporopollenin is resilient to chemical degradation. Because of this stability, its exact chem…

Demystifying and Unravelling the Factual Molecular Structure of the Biopolymer Sporopollenin Open

Abanoub Mikhael, Kristina Jurčić, C. Schneider, David carr, Gregory L. Fisher , et al. · 2019

Sporopollenin is a natural highly cross-linked biopolymer composed of carbon, hydrogen, and oxygen which forms the outer wall of pollen grains. Sporopollenin is resilient to chemical degradation. Because of this stability, its exact chemic…

Demystifying and Unravelling the Factual Molecular Structure of the Biopolymer Sporopollenin Open

Abanoub Mikhael, Kristina Jurčić, C. Schneider, David carr, Gregory L. Fisher , et al. · 2019

Sporopollenin is a natural, highly cross-linked biopolymer composed of carbon, hydrogen, and oxygen, which forms the outer wall of pollen grains. Sporopollenin is resilient to chemical degradation.Because of this stability, its…

OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness Open

Elisa Comisso, Michele Scarola, M Rosso, Silvano Piazza, Stefania Marzinotto , et al. · 2017

Nanoscale patterning of self-assembled monolayer (SAM)-functionalised substrates with single molecule contact printing Open

Martin Sajfutdinow, Katja Uhlig, Andrea Prager, C. Schneider, Bernd Abel , et al. · 2017

DNA origami stamps print biomolecules onto SAM-coated gold filmsviabioconjugation in a process called single molecule contact printing.

Calpain restrains the stem cells compartment in breast cancer Open

Marzia Raimondi, Elena Marcassa, Francesca Cataldo, Teresa Arnandis, Ramiro Mendoza-Maldonado , et al. · 2016

CAPNS1 is essential for the stability and function of ubiquitous CAPN1 and CAPN2. Calpain modulates by proteolytic cleavage many cellular substrates and its activity is often deregulated in cancer cells, therefore calpain inhibition has be…

Determining the structural stability of UiO-67 with respect to time: a solid-state NMR investigation Open

Mason C. Lawrence, C. Schneider, Michael J. Katz · 2016

Revealing defects, the stability of UiO-67 was studied with SS-NMR as a function of time and activation method/solvent.

CCDC 1403400: Experimental Crystal Structure Determination Open

Marcus W. Drover, Jennifer N. Murphy, Jenna Flogeras, C. Schneider, Louise N. Dawe , et al. · 2015

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1403401: Experimental Crystal Structure Determination Open

Marcus W. Drover, Jennifer N. Murphy, Jenna Flogeras, C. Schneider, Louise N. Dawe , et al. · 2015

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

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