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View article: Optic Disc Flavoprotein Fluorescence Imaging as a Novel Method to Quantify Disease Burden in Optic Disc Drusen
Optic Disc Flavoprotein Fluorescence Imaging as a Novel Method to Quantify Disease Burden in Optic Disc Drusen Open
Disc FPF is an objective imaging technique to quantify disease burden in ODD, reflecting a combination of drusen autofluorescence signal and metabolic stress from axonopathy. Disc FPF is correlated with structural and functional changes an…
View article: Characterizing Retinal Mitochondrial Function and Its Relations to Intraretinal Thicknesses in Healthy Adults
Characterizing Retinal Mitochondrial Function and Its Relations to Intraretinal Thicknesses in Healthy Adults Open
This study is the first to examine the relationship between retinal mitochondrial function and intraretinal layer thicknesses in healthy adults. Findings suggest that age mediates the observed associations.
View article: Flavoprotein fluorescence elevation is a marker of mitochondrial oxidative stress in patients with retinal disease
Flavoprotein fluorescence elevation is a marker of mitochondrial oxidative stress in patients with retinal disease Open
Purpose Recent studies of glaucoma, age-related macular degeneration, and diabetic retinopathy have demonstrated that flavoprotein fluorescence (FPF) can be utilized non-invasively as an indicator of mitochondrial oxidative stress in the r…
View article: Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence
Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence Open
Whether by indirect oxidative stress or direct genetic defect, various genetic retinal dystrophies involve mitochondrial stress. Mitochondrial flavoprotein fluorescence (FPF), reported as either average signal intensity or variability (het…
View article: Structural and Metabolic Imaging After Short-term Use of the Balance Goggles System in Glaucoma Patients: A Pilot Study
Structural and Metabolic Imaging After Short-term Use of the Balance Goggles System in Glaucoma Patients: A Pilot Study Open
Précis: Short-term use of the Balance Goggles System (BGS) in glaucoma patients was not associated with the observable changes in conventional ocular coherence tomography (OCT) imaging, but metabolic imaging using peripapillary flavoprotei…
View article: Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence
Functional imaging of mitochondria in genetically confirmed retinal dystrophies using flavoprotein fluorescence Open
Whether by indirect oxidative stress or direct genetic defect, various genetic retinal dystrophies involve mitochondrial stress. Mitochondrial flavoprotein fluorescence (FPF), reported as either average signal intensity or variability (het…