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View article: Autologous neutralizing antibodies increase with early antiretroviral therapy and shape HIV rebound after treatment interruption
Autologous neutralizing antibodies increase with early antiretroviral therapy and shape HIV rebound after treatment interruption Open
Early initiation of antiretroviral therapy (ART) alters viral rebound kinetics after analytic treatment interruption (ATI) and may play a role in promoting HIV-1 remission. Autologous neutralizing antibodies (aNAbs) represent a key adaptiv…
View article: Viral and Host Mediators of Non-Suppressible HIV-1 Viremia
Viral and Host Mediators of Non-Suppressible HIV-1 Viremia Open
Non-suppressible HIV-1 viremia (NSV) can occur in persons with HIV despite adherence to combination antiretroviral therapy (ART) and in the absence of significant drug resistance. Here, we show that plasma NSV sequences are comprised prima…
View article: High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro
High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro Open
Influenza and other respiratory viruses present a significant threat to public health, national security, and the world economy, and can lead to the emergence of global pandemics such as from COVID-19. A barrier to the development of effec…
View article: Liver Fibrosis Index FIB‐4 Is Associated With Mortality in COVID‐19
Liver Fibrosis Index FIB‐4 Is Associated With Mortality in COVID‐19 Open
Coronavirus disease 2019 (COVID‐19) is associated with adverse outcomes, including need for invasive mechanical ventilation and death in people with risk factors. Liver enzyme elevation is commonly seen in this group, but its clinical sign…
View article: SARS-CoV-2 Viral Load is Associated with Increased Disease Severity and Mortality
SARS-CoV-2 Viral Load is Associated with Increased Disease Severity and Mortality Open
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). We quantified SARS-CoV-2 viral load from participants with a diverse range of COVID-19 severit…
View article: SARS-CoV-2 Viral Load is Associated with Increased Disease Severity and Mortality
SARS-CoV-2 Viral Load is Associated with Increased Disease Severity and Mortality Open
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). We quantified SARS-CoV-2 viral load from participants with a diverse range of COVID-19 severit…